There are 7 ways to get from Appleton to Sanibel Island by plane, bus (Flixbus, Greyhound), bus, train, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Appleton International Airport to Ft. Myers
best- Fly from Appleton International Airport (ATW) to Ft. Myers (RSW)plane ATW - RSW
4h$199–752Bus
- Take the bus from Appleton Transit Center to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Tampa Bus Stationbus
- Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus
36h 53m$255–421Bus, train
- Take the bus from Appleton Transit Center to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Tampatrain
- Take the bus from Tampa to Fort Myers Amtrak Bus Stopbus
2d 3h$564–1,278Drive 1,428.7 mi
- Drive from Appleton to Sanibel Islandcar 1,428.7 mi
26h 8m$261–377Fly Appleton International Airport to Punta Gorda Airport, taxi
- Fly from Appleton International Airport (ATW) to Punta Gorda Airport (PGD)plane ATW - PGD
- Take the taxi from Punta Gorda Airport (PGD) to Sanibel Islandtaxi
4h 13m$224–707Fly Green Bay to Ft. Myers
- Fly from Green Bay (GRB) to Ft. Myers (RSW)plane GRB - RSW
7h 44m$221–777Bus to General Mitchell International Airport, fly to Ft. Myers
- Take the bus from Appleton to Milwaukee Airportbus
- Fly from General Mitchell International Airport (MKE) to Ft. Myers (RSW)plane MKE - RSW
7h 25m$242–910
Appleton International Airport (ATW) to Ft. Myers (RSW) flights
Comparing Your Travel Options
The cheapest way to get from Appleton to Sanibel Island is to drive which costs $260 - $380 and takes 26h 8m.
The fastest way to get from Appleton to Sanibel Island is to fly which takes 4h and costs $190 - $750.
No, there is no direct bus from Appleton to Sanibel Island. However, there are services departing from Appleton Transit Center and arriving at Cape Coral Transfer Center via Chicago Bus Station, Atlanta Bus Station, Tampa Bus Station and Rosa Parks Transportation Ctr. The journey, including transfers, takes approximately 36h 53m.
The distance between Appleton and Sanibel Island is 1318 miles. The road distance is 1437 miles.
The best way to get from Appleton to Sanibel Island without a car is to bus which takes 36h 53m and costs $250 - $430.
It takes approximately 4h to get from Appleton to Sanibel Island, including transfers.
Appleton to Sanibel Island bus services, operated by Flixbus USA, depart from Appleton Transit Center station.
The best way to get from Appleton to Sanibel Island is to fly which takes 4h and costs $190 - $750. Alternatively, you can bus, which costs $250 - $430 and takes 36h 53m.
Appleton to Sanibel Island bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Yes, the driving distance between Appleton to Sanibel Island is 1437 miles. It takes approximately 26h 8m to drive from Appleton to Sanibel Island.
What companies run services between Appleton, WI, USA and Sanibel Island, FL, USA?
Allegiant Air, Delta, and two other airlines fly from Appleton International Airport (ATW) to Ft. Myers (RSW) every 3 hours. Alternatively, you can take a bus from Appleton Transit Center to Sanibel Island via Chicago Bus Station, Atlanta Bus Station, Tampa Bus Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 36h 53m.
- Website
- delta.com
Flights from Appleton International Airport to Ft. Myers via Atlanta
- Ave. Duration
- 6h 28m
- When
- Every day
- Estimated price
- $120–650
Flights from Appleton International Airport to Ft. Myers via Minneapolis
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $150–700
Flights from Appleton International Airport to Ft. Myers via Detroit
- Ave. Duration
- 7h 18m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
Flights from Green Bay to Ft. Myers via Atlanta
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $120–650
Flights from Green Bay to Ft. Myers via Minneapolis
- Ave. Duration
- 7h 38m
- When
- Every day
- Estimated price
- $150–700
Flights from Green Bay to Ft. Myers via Detroit
- Ave. Duration
- 9h 18m
- When
- Every day
- Estimated price
- $130–650
Flights from General Mitchell International Airport to Ft. Myers via Atlanta
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $160–800
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Tampa
- Ave. Duration
- 40h 47m
- Frequency
- Once daily
- Estimated price
- $440–1,100
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Appleton Transit Center to Chicago Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a week
- Estimated price
- $29–45
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 15h 40m
- Frequency
- Twice daily
- Estimated price
- $100–170
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Tampa Bus Station
- Ave. Duration
- 8h 20m
- Frequency
- 5 times a week
- Estimated price
- $65–110
- Schedules at
- Flixbus USA
Bus from Tampa Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 3h 5m
- Frequency
- 3 times a day
- Estimated price
- $20–30
- Schedules at
- Flixbus USA
Bus from Appleton Transit Center to Chicago Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a week
- Estimated price
- $29–45
- Schedules at
- Flixbus USA
Bus from Appleton to Milwaukee Airport
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a week
- Estimated price
- $16–26
- Schedules at
- Flixbus USA
- Ave. Duration
- 59 min
- Estimated price
- $110–140
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
Want to know more about travelling around United States
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Booking & Getting There
There are 4361+ hotels available in Sanibel Island.




