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How to get fromAppleton to Syracuseby plane, bus, train, bus (Flixbus, Greyhound), or car

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There are 8 ways to get from Appleton to Syracuse by plane, bus, train, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Appleton International Airport to Syracuse Hancock International Airport

    best
    1. Fly from Appleton International Airport (ATW) to Syracuse Hancock International Airport (SYR)plane plane ATW - SYR
    5h 39m
    $145–725

  2. Fly Appleton International Airport to Greater Binghamton Airport, bus

    cheapest
    1. Fly from Appleton International Airport (ATW) to Greater Binghamton Airport (BGM)plane plane ATW - BGM
    2. Take the bus from Binghamton to Syracusebus bus
    8h 4m
    $131–465

  3. Bus, train

    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus FlixBus 2550
    2. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain train Lake Shore Limited
    18h 37m
    $241–491

  4. Bus

    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Syracuse Bus Stationbus bus
    20h 30m
    $136–271

  5. Drive 865.6 mi

    1. Drive from Appleton to Syracusecar car 865.6 mi
    14h 56m
    $158–229

  6. Fly Appleton International Airport to Rochester, train

    1. Fly from Appleton International Airport (ATW) to Rochester (ROC)plane plane ATW - ROC
    2. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    6h 5m
    $163–799

  7. Fly Green Bay to Syracuse Hancock International Airport

    1. Fly from Green Bay (GRB) to Syracuse Hancock International Airport (SYR)plane plane GRB - SYR
    7h 33m
    $167–750

  8. Bus, train via Milwaukee

    1. Take the bus from Appleton to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain train
    19h 2m
    $254–528

Appleton to Syracuse by bus, foot, and train

Calendar5Weekly Services
Duration18h 37mAverage Duration
Ticket$241Cheapest Price
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Questions & Answers

Map of how to get from Appleton to Syracuse.ExpandLaunch map view
  • Distance: 640.6 mi
  • Duration: 5h 39m

What companies run services between Appleton, WI, USA and Syracuse, NY, USA?

Delta, American Airlines, and United Airlines fly from Appleton International Airport (ATW) to Syracuse Hancock International Airport (SYR) every 4 hours. Alternatively, you can take a bus from Appleton Transit Center to Syracuse Bus Station via Chicago Bus Station and Cleveland Bus Station in around 20h 30m.

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