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How to get fromArequipa to Santa Cruzby plane, bus, or car

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There are 5 ways to get from Arequipa to Santa Cruz by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Rodríguez Ballón International Airport

    best
    1. Fly from Rodríguez Ballón International Airport (AQP) to Viru Viru International Airport (VVI)plane plane AQP - VVI
    9h
    $350–501

  2. Bus

    cheapest
    1. Take the bus from Arequipa to La Pazbus bus
    2. Take the bus from La Paz to Santa Cruzbus bus La Paz
    31h 4m
    $57–117

  3. Bus via Cochabamba

    1. Take the bus from Arequipa to La Pazbus bus
    2. Take the bus from La Paz to Cochabambabus bus
    3. Take the bus from Cochabamba to Santa Cruz de la Sierrabus bus
    28h 31m
    $63–328

  4. Drive 1,303.5 km

    1. Drive from Arequipa to Santa Cruz de la Sierracar car 1,303.5 km
    20h 53m
    $196–283

  5. Bus to El Alto International Airport, fly

    1. Take the bus from Arequipa to La Pazbus bus
    2. Fly from El Alto International Airport (LPB) to Viru Viru International Airport (VVI)plane plane LPB - VVI
    15h 53m
    $152–273

Rodríguez Ballón International Airport (AQP) to Viru Viru International Airport (VVI) flights

Calendar16Weekly Planes
Duration8h 27mAverage Duration
Ticket$205Cheapest Price
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Questions & Answers

Map of how to get from Arequipa to Santa Cruz.ExpandLaunch map view
  • Distance: 935.7 km
  • Duration: 9h

What companies run services between Arequipa, Peru and Santa Cruz, Bolivia?

LATAM Chile, Sky Airline, and Boliviana de Aviación fly from Rodríguez Ballón International Airport (AQP) to Viru Viru International Airport (VVI) twice daily. Alternatively, you can take a bus from Arequipa to Santa Cruz de la Sierra via La Paz, Cochabamba, Plaza Colón, Avenida República, Cochabamba, and Santa Cruz de la Sierra in around 28h 31m.

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