There are 5 ways to get from Arequipa to Santa Cruz de la Sierra by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Rodríguez Ballón International Airport
best- Fly from Rodríguez Ballón International Airport (AQP) to Viru Viru International Airport (VVI)plane AQP - VVI
9h$350–501Bus
cheapest- Take the bus from Arequipa to La Pazbus
- Take the bus from La Paz to Santa Cruzbus La Paz
31h$55–113Bus via Cochabamba
- Take the bus from Arequipa to La Pazbus
- Take the bus from La Paz to Cochabambabus
- Take the bus from Cochabamba to Santa Cruz de la Sierrabus
28h 26m$61–324Drive 1,303.5 km
- Drive from Arequipa to Santa Cruz de la Sierracar 1,303.5 km
20h 53m$196–283Bus to El Alto International Airport, fly
- Take the bus from Arequipa to La Pazbus
- Fly from El Alto International Airport (LPB) to Viru Viru International Airport (VVI)plane LPB - VVI
15h 53m$152–273
Rodríguez Ballón International Airport (AQP) to Viru Viru International Airport (VVI) flights
Questions & Answers
The cheapest way to get from Arequipa to Santa Cruz de la Sierra is to bus which costs $55 - $120 and takes 31h.
The fastest way to get from Arequipa to Santa Cruz de la Sierra is to fly which takes 9h and costs $350 - $500.
No, there is no direct bus from Arequipa to Santa Cruz de la Sierra. However, there are services departing from Arequipa and arriving at Santa Cruz de la Sierra via La Paz, Plaza Colón and Cochabamba. The journey, including transfers, takes approximately 28h 26m.
The distance between Arequipa and Santa Cruz de la Sierra is 936 km. The road distance is 1303.5 km.
The best way to get from Arequipa to Santa Cruz de la Sierra without a car is to bus via Cochabamba which takes 28h 26m and costs $60 - $330.
It takes approximately 9h to get from Arequipa to Santa Cruz de la Sierra, including transfers.
Arequipa to Santa Cruz de la Sierra bus services, operated by Nuevo Continente Internacional, depart from Arequipa station.
The best way to get from Arequipa to Santa Cruz de la Sierra is to fly which takes 9h and costs $350 - $500. Alternatively, you can bus via Cochabamba, which costs $60 - $330 and takes 28h 26m.
Arequipa to Santa Cruz de la Sierra bus services, operated by Nuevo Continente Internacional, arrive at La Paz station.
Santa Cruz de la Sierra is 1h ahead of Arequipa. It is currently 11:11 PM in Arequipa and 12:11 AM in Santa Cruz de la Sierra.
What companies run services between Arequipa, Peru and Santa Cruz de la Sierra, Bolivia?
LATAM Chile, Sky Airline, and Boliviana de Aviación fly from Rodríguez Ballón International Airport (AQP) to Viru Viru International Airport (VVI) twice daily. Alternatively, you can take a bus from Arequipa to Santa Cruz de la Sierra via La Paz, Cochabamba, Plaza Colón, Avenida República, and Cochabamba in around 28h 26m.
- Website
- boa.bo
Flights from Rodríguez Ballón International Airport to Viru Viru International Airport via Lima
- Ave. Duration
- 5h 55m
- When
- Every day
- Estimated price
- $240–750
Flights from El Alto International Airport to Viru Viru International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $100–220
Flights from El Alto International Airport to Viru Viru International Airport via Cochabamba
- Ave. Duration
- 2h 23m
- When
- Every day
- Estimated price
- $50–310
- Website
- latam.com
Flights from Rodríguez Ballón International Airport to Viru Viru International Airport via Lima
- Ave. Duration
- 6h 15m
- When
- Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–750
Flights from Rodríguez Ballón International Airport to Viru Viru International Airport via Cuzco, Lima
- Ave. Duration
- 9h 30m
- When
- Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–750
Flights from Rodríguez Ballón International Airport to Viru Viru International Airport via Lima, El Alto International Airport
- Ave. Duration
- 12h 9m
- When
- Wednesday
- Estimated price
- $200–750
Flights from El Alto International Airport to Viru Viru International Airport
- Ave. Duration
- 1h 13m
- When
- Thursday and Saturday
- Estimated price
- $75–500
- Website
- ecojet.bo
Flights from El Alto International Airport to Viru Viru International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $50–310
- Phone
- +591 22283843
- [email protected]
- Website
- facebook.com
Bus from Arequipa to La Paz
- Ave. Duration
- 13h
- Frequency
- Once daily
- Estimated price
- $50–320
- Book at
- Tickets Bolivia
- Phone
- +59176401000
- Website
- facebook.com
Bus from La Paz to Cochabamba
- Ave. Duration
- 7h 45m
- Frequency
- 5 times a day
- Estimated price
- $9
- Book at
- ticketsbolivia.com.bo
- Phone
- +591 72201573
- [email protected]
- Website
- Minibuses Trans Carrasco tropical
Bus from Cochabamba to Santa Cruz de la Sierra
- Ave. Duration
- 6h
- Frequency
- Hourly
- Estimated price
- $2
- Website
- Minibuses Trans Carrasco tropical
- Phone
- +591 2245 8945
- [email protected]
- Website
- vicuna-travel.com
Bus from Arequipa to La Paz
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $49
- Schedules at
- ticketsbolivia.com.bo
- Book at
- ticketsbolivia.com.bo
Bus from Arequipa to La Paz
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $49
- Schedules at
- ticketsbolivia.com.bo
- Book at
- ticketsbolivia.com.bo
- Phone
- +591-72233555
- [email protected]
- Website
- Trans Copacabana SA
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- 4 times a day
- Estimated price
- $19–25
- Schedules at
- Trans Copacabana SA
- Phone
- +591 7297 1111
- Website
- Expreso del Sur
Bus from La Paz to Santa Cruz
- Ave. Duration
- 14h
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- Expreso del Sur
- Phone
- +591 69414917
- Website
- Flota Bolivar
Bus from La Paz to Santa Cruz
- Ave. Duration
- 16h 20m
- Frequency
- Once daily
- Estimated price
- $7–19
- Schedules at
- Flota Bolivar
- Normal
- $7–10
- Semicama
- $11–14
- Cama
- $17–19
- Phone
- +591 69416892
- [email protected]
- Website
- Cosmos
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $9–13
- Schedules at
- Cosmos
- Phone
- +59176400493
- Website
- flotaeldorado.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $19–65
- Schedules at
- flotaeldorado.com
- Book at
- flotaeldorado.com
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More Questions & Answers
Yes, the driving distance between Arequipa to Santa Cruz de la Sierra is 1303 km. It takes approximately 20h 53m to drive from Arequipa to Santa Cruz de la Sierra.
There are 726+ hotels available in Santa Cruz de la Sierra.


















