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How to get fromArezzo to Iserniaby train (Trenitalia), bus, train, or car

Find Transport to Isernia

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There are 5 ways to get from Arezzo to Isernia by train (Trenitalia), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Arezzo to Napoli Afragolatrain train Fr
    2. Take the train from Napoli Afragola to Iserniatrain train Re
    5h 19m
    €71–115

  2. Bus

    cheapest
    1. Take the bus from Arezzo to Perugiabus bus 504
    2. Take the bus from Perugia to Roma, Autostazione Tiburtinabus bus 538 / ...
    3. Take the bus from Roma, Autostazione Tiburtina to Iserniabus bus
    7h 50m
    €26–59

  3. Bus, train

    1. Take the bus from Arezzo Terminal to Bettolle Piazza Del Popolobus bus Ls5
    2. Take the bus from Bettole - Uff.PT Bettolle to Cassinobus bus
    3. Take the train from Cassino to Iserniatrain train Re
    6h 46m
    €30–41

  4. Drive  369 km

    1. Drive from Arezzo to Iserniacar car 369 km
    3h 41m
    €60–87

  5. Train via Rome (Trenitalia)

    1. Take the train from Arezzo to Roma Tiburtinatrain train 4113 / ...
    2. Take the train from Roma Tiburtina to Iserniatrain train Re
    5h 31m
    €45–78

Arezzo to Isernia by train (Trenitalia)

Calendar6Weekly Trains
Duration5h 19mAverage Duration
Ticket€71Cheapest Price
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Comparing Your Travel Options

Map of how to get from Arezzo to Isernia.ExpandLaunch map view
  • Distance: 525.2 km
  • Duration: 5h 19m

What companies run services between Arezzo, Italy and Isernia, Italy?

You can take a train from Arezzo to Isernia via Napoli Afragola in around 5h 19m. Alternatively, you can take a bus from Arezzo to Isernia via Perugia and Roma, Autostazione Tiburtina in around 7h 50m.

Train operators
Bus operators

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