There are 5 ways to get from Argonne National Lab to Buffalo by plane, train (Amtrak), bus, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane MDW - BUF
2h 40m$147–512Bus
cheapest- Take the bus from Chicago to Clevelandbus Chicago
- Take the bus from Cleveland, OH to Buffalo, NYbus Cinncinati,OH-Buffalo
15h 36m$55–148Train (Amtrak)
- Take the train from Chicago Union Station to Buffalo Depew Stationtrain Lake Shore Limited
13h 46m$193–516Drive 542 mi
- Drive from Argonne National Lab to Buffalocar 542 mi
9h 23m$99–143Bus via Detroit
- Take the bus from Chicago to Detroit Bus Stationbus
- Take the bus from Detroit Bus Station to Torontobus
- Take the bus from Toronto to Buffalobus
21h 3m$130–224
Argonne National Lab to Buffalo by bus and foot
Questions & Answers
The cheapest way to get from Argonne National Lab to Buffalo is to bus which costs $55 - $150 and takes 15h 36m.
The fastest way to get from Argonne National Lab to Buffalo is to fly which takes 2h 40m and costs $140 - $550.
No, there is no direct bus from Argonne National Lab to Buffalo. However, there are services departing from Argonne National Lab and arriving at Buffalo, NY via Yorktown Center, Lake St & Austin Blvd, Jackson & Austin Terminal, Chicago and Cleveland, OH. The journey, including transfers, takes approximately 15h 36m.
No, there is no direct train from Argonne National Lab to Buffalo. However, there are services departing from Fairview Ave. and arriving at Buffalo via Chicago Union Station and Buffalo Depew Station. The journey, including transfers, takes approximately 13h 46m.
The distance between Argonne National Lab and Buffalo is 498 miles. The road distance is 545.2 miles.
The best way to get from Argonne National Lab to Buffalo without a car is to train which takes 13h 46m and costs $190 - $550.
It takes approximately 2h 40m to get from Argonne National Lab to Buffalo, including transfers.
Argonne National Lab to Buffalo bus services, operated by Barons Bus, depart from Chicago station.
Argonne National Lab to Buffalo train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Argonne National Lab to Buffalo is to fly which takes 2h 40m and costs $140 - $550. Alternatively, you can train, which costs $190 - $550 and takes 13h 46m, you could also bus, which costs $55 - $150 and takes 15h 36m.
What companies run services between Argonne National Lab, IL, USA and Buffalo, NY, USA?
Southwest Airlines and Delta fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF) 4 times a day. Alternatively, Amtrak operates a train from Chicago Union Station to Buffalo Depew Station twice daily. Tickets cost $170–350 and the journey takes 10h 23m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $120–700
- Website
- delta.com
Flights from Chicago Midway International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- $120–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Buffalo Depew Station
- Ave. Duration
- 10h 23m
- Frequency
- Twice daily
- Estimated price
- $170–350
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Chicago to Cleveland
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $18–60
- Website
- https://baronsbus.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Chicago to Detroit Bus Station
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $50–90
- Schedules at
- flixbus.com
Bus from Detroit Bus Station to Toronto
- Ave. Duration
- 6h 25m
- Frequency
- 4 times a day
- Estimated price
- $35–65
- Schedules at
- flixbus.com
Bus from Toronto to Buffalo
- Ave. Duration
- 3h 5m
- Frequency
- 4 times a day
- Estimated price
- $16–27
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Toronto to Buffalo
- Ave. Duration
- 2h 55m
- Frequency
- 4 times a day
- Estimated price
- $22–60
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $22–60
- Flexible
- $40–60
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Toronto to Buffalo
- Ave. Duration
- 2h 45m
- Frequency
- 3 times a day
- Estimated price
- $16–35
- Website
- https://www.greyhound.com/
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More Questions & Answers
Argonne National Lab to Buffalo bus services, operated by Barons Bus, arrive at Cleveland station.
Buffalo is 1h ahead of Argonne National Lab. It is currently 10:56 AM in Argonne National Lab and 11:56 AM in Buffalo.
Argonne National Lab to Buffalo train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between Argonne National Lab to Buffalo is 545 miles. It takes approximately 9h 23m to drive from Argonne National Lab to Buffalo.
There are 231+ hotels available in Buffalo.












