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How to get fromArkansas to Mayo Clinicby plane, bus, train, or car

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There are 8 ways to get from Arkansas to Mayo Clinic by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Northwest Arkansas Regional Airport to Rochester

    best
    1. Fly from Northwest Arkansas Regional Airport (XNA) to Rochester (RST)plane plane XNA - RST
    5h 56m
    $126–557

  2. Fly Bill And Hillary Clinton National Airport to Rochester

    cheapest
    1. Fly from Bill And Hillary Clinton National Airport (LIT) to Rochester (RST)plane plane LIT - RST
    6h 36m
    $98–480

  3. Bus

    1. Take the bus from Shell gas station - Little Rock, AR to Water & Chicago - Circle Kbus bus Milwaukee
    2. Take the bus from Milwaukee to Rochesterbus bus Jefferson Lines 966
    23h 22m
    $222–273

  4. Train, bus via Madison

    1. Take the train from Union Station to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    23h 51m
    $229–494

  5. Drive  756.2 mi

    1. Drive from Little Rock to Mayo Cliniccar car 756.2 mi
    14h 5m
    $138–200

  6. Fly Northwest Arkansas Regional Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Northwest Arkansas Regional Airport (XNA) to Minneapolis–Saint Paul International Airport (MSP)plane plane XNA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    5h 9m
    $187–699

  7. Train, bus

    1. Take the train from Union Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    25h 9m
    $282–644

  8. Train, bus via Kansas City

    1. Take the train from Union Station to Longviewtrain train
    2. Take the bus from Longview Bus Station to Texarkanabus bus
    3. Take the bus from Texarkana to Kansas Citybus bus
    4. Take the bus from Kansas City to Owatonnabus bus
    5. Take the bus from Owatonna to Rochesterbus bus
    29h 36m
    $284–501

Arkansas to Mayo Clinic by train, bus, and foot

Calendar7Weekly Services
Duration23h 51mAverage Duration
Ticket$229Cheapest Price
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Comparing Your Travel Options

Map of how to get from Arkansas to Mayo Clinic.ExpandLaunch map view
  • Distance: 558 mi
  • Duration: 5h 56m

What companies run services between Arkansas, USA and Mayo Clinic, MN, USA?

Delta, American Airlines, and United Airlines fly from Northwest Arkansas Regional Airport (XNA) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from MLK Dr@7th to Mayo Clinic via River Cities, WalmartBaseline, Shell gas station - Little Rock, AR, Water & Chicago - Circle K, Milwaukee, and Rochester in around 23h 22m.

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