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How to get fromAsheville to Des Moinesby plane, bus, train, car, or bus (Greyhound)

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There are 9 ways to get from Asheville to Des Moines by plane, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Asheville Regional Airport

    best
    1. Fly from Asheville Regional Airport (AVL) to Des Moines (DSM)plane plane AVL - DSM
    6h 6m
    $158–722

  2. Bus, train via Ironville

    1. Take the bus from Asheville, NC to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Ashlandbus bus
    3. Take the train from Ashland Amtrak Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    28h 41m
    $205–433

  3. Bus, train

    1. Take the bus from Asheville, NC to Greensboro Bus Stopbus bus
    2. Take the train from Greensboro to Carytrain train
    3. Take the train from Cary to Chicago Union Stationtrain train
    4. Take the bus from Chicago to Des Moinesbus bus
    40h 18m

  4. Drive 894 mi

    1. Drive from Asheville to Des Moinescar car 894 mi
    16h 29m
    $164–236

  5. Drive to Greenville–Spartanburg International Airport, fly

    1. Drive from Asheville to Greenville–Spartanburg International Airport (GSP)car car
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Des Moines (DSM)plane plane GSP - DSM
    6h 3m
    $209–938

  6. Bus to Charlotte Douglas International Airport, fly

    1. Take the bus from Asheville, NC to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM)plane plane CLT - DSM
    7h 3m

  7. Drive to Mcghee Tyson Airport, fly

    1. Drive from Asheville to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Des Moines (DSM)plane plane TYS - DSM
    7h 5m
    $218–1,001

  8. Bus

    1. Take the bus from Asheville, NC to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte to Columbusbus bus
    3. Take the bus from Wilson & Ferrell Shell Station - Columbus to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis to Des Moinesbus bus
    32h 35m

  9. Bus, train #2

    1. Take the bus from Asheville, NC to Greensboro Bus Stopbus bus
    2. Take the train from Greensboro to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    5. Take the bus from Galesburg to Des Moinesbus bus
    41h 1m
    $473–982

Asheville to Des Moines by bus and train

Calendar3Weekly Services
Duration28h 41mAverage Duration
Ticket$205Cheapest Price
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Questions & Answers

Map of how to get from Asheville to Des Moines.ExpandLaunch map view
  • Distance: 752.3 mi
  • Duration: 6h 6m

What companies run services between Asheville, NC, USA and Des Moines, IA, USA?

Delta, American Airlines, and United Airlines fly from Asheville Regional Airport (AVL) to Des Moines (DSM) every 2 hours. Alternatively, you can take a bus from Asheville, NC to Des Moines via Charlotte, Wilson & Ferrell Shell Station - Columbus, and Indianapolis in around 32h 35m.

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