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How to get fromAsheville to Des Moinesby plane, bus (Greyhound), bus, train, or car

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There are 8 ways to get from Asheville to Des Moines by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Asheville Regional Airport

    best
    1. Fly from Asheville Regional Airport (AVL) to Des Moines (DSM)plane plane AVL - DSM
    6h 9m
    $98–444

  2. Bus

    1. Take the bus from Asheville, NC to Greensboro Bus Stopbus bus
    2. Take the bus from Greensboro to Winston-Salembus bus
    3. Take the bus from Winston Salem to Columbusbus bus
    4. Take the bus from Columbus to Indianapolis Union Stationbus bus
    5. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    31h 15m
    $187–314

  3. Bus, train

    1. Take the bus from Asheville, NC to Greensboro Bus Stopbus bus
    2. Take the train from Greensboro to Charlottesvilletrain train
    3. Take the train from Charlottesville to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    34h 58m
    $536–865

  4. Drive  894 mi

    1. Drive from Asheville to Des Moinescar car 894 mi
    16h 29m
    $164–236

  5. Drive to Greenville–Spartanburg International Airport, fly

    1. Drive from Asheville to Greenville–Spartanburg International Airport (GSP)car car
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Des Moines (DSM)plane plane GSP - DSM
    6h 9m
    $115–490

  6. Drive to Mcghee Tyson Airport, fly

    1. Drive from Asheville to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Des Moines (DSM)plane plane TYS - DSM
    7h 12m
    $129–603

  7. Bus, train via Chicago

    1. Take the bus from Asheville, NC to Raleigh Bus Stationbus bus
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    38h 51m
    $653–1,110

  8. Bus, train via Galesburg

    1. Take the bus from Asheville, NC to Greensboro Bus Stopbus bus
    2. Take the train from Greensboro to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    5. Take the bus from Galesburg to Des Moinesbus bus
    41h 1m
    $741–1,260

Asheville to Des Moines by bus

Calendar7Weekly Buses
Duration31h 15mAverage Duration
Ticket$187Cheapest Price
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Comparing Your Travel Options

Map of how to get from Asheville to Des Moines.ExpandLaunch map view
  • Distance: 752.3 mi
  • Duration: 6h 9m

What companies run services between Asheville, NC, USA and Des Moines, IA, USA?

United Airlines, Delta, and two other airlines fly from Asheville Regional Airport (AVL) to Des Moines (DSM) every 2 hours. Alternatively, you can take a bus from Asheville, NC to Des Moines via Greensboro, Winston Salem, Columbus, and Indianapolis Union Station in around 31h 15m.

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