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How to get fromAsheville to St. Louisby car, plane, taxi, bus, train, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Asheville to St. Louis by car, plane, taxi, bus, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Greenville–Spartanburg International Airport, fly

    best
    1. Drive from Asheville to Greenville–Spartanburg International Airport (GSP)car car
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Lambert–St. Louis International Airport (STL)plane plane GSP - STL
    5h 45m
    $115–620

  2. Fly from Asheville Regional Airport

    cheapest
    1. Fly from Asheville Regional Airport (AVL) to Lambert–St. Louis International Airport (STL)plane plane AVL - STL
    6h 16m
    $98–554

  3. Taxi, bus

    1. Take the taxi from WNC Ag Center Park-n-Ride to Taqueria Guadalajara - Greenvilletaxi taxi
    2. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    19h 30m
    $254–404

  4. Drive  587.6 mi

    1. Drive from Asheville to St. Louiscar car 587.6 mi
    10h 8m
    $108–155

  5. Drive to Mcghee Tyson Airport, fly

    1. Drive from Asheville to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Lambert–St. Louis International Airport (STL)plane plane TYS - STL
    7h 9m
    $109–583

  6. Bus, train

    1. Take the bus from Asheville, NC to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Ashlandbus bus
    3. Take the train from Ashland Amtrak Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    22h 41m
    $155–342

  7. Bus via Charlotte

    1. Take the bus from Asheville, NC to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Atlanta Downtownbus bus
    4. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    22h 49m
    $152–297

  8. Bus

    1. Take the bus from Asheville, NC to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    23h 5m
    $153–307

Asheville to St. Louis by bus and train

Calendar3Weekly Services
Duration22h 41mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

Map of how to get from Asheville to St. Louis.ExpandLaunch map view
  • Distance: 601.5 mi
  • Duration: 5h 45m

What companies run services between Asheville, NC, USA and St. Louis, MO, USA?

Delta, American Airlines, and United Airlines fly from Asheville Regional Airport (AVL) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from Asheville, NC to St Louis Bus Station via Winston Salem(Trans Center), Charlotte Bus Station, Atlanta Downtown, Civic Center Station, Garnett Station, and Atlanta Bus Station in around 22h 49m.

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