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How to get fromAsheville to St. Louisby car, plane, bus (Flixbus, Greyhound), bus, or bus (Greyhound)

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There are 8 ways to get from Asheville to St. Louis by car, plane, bus (Flixbus, Greyhound), bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Greenville–Spartanburg International Airport, fly

    best
    1. Drive from Asheville to Greenville–Spartanburg International Airport (GSP)car car
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Lambert–St. Louis International Airport (STL)plane plane GSP - STL
    5h 26m
    $125–670

  2. Fly from Asheville Regional Airport

    cheapest
    1. Fly from Asheville Regional Airport (AVL) to Lambert–St. Louis International Airport (STL)plane plane AVL - STL
    5h 55m
    $104–554

  3. Bus

    1. Take the bus from Asheville, NC to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    19h 30m
    $158–297

  4. Drive 587.6 mi

    1. Drive from Asheville to St. Louiscar car 587.6 mi
    10h 8m
    $108–155

  5. Drive to Mcghee Tyson Airport, fly

    1. Drive from Asheville to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Lambert–St. Louis International Airport (STL)plane plane TYS - STL
    6h 34m
    $134–733

  6. Bus to Charlotte Douglas International Airport, fly

    1. Take the bus from Asheville, NC to Charlotte Bus Stationbus bus
    2. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane plane CLT - STL
    7h 9m
    $165–711

  7. Bus via Atlanta

    1. Take the bus from Asheville, NC to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Atlanta Downtownbus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    19h 39m
    $161–290

  8. Bus via Columbus

    1. Take the bus from Asheville, NC to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    3. Take the bus from Columbus to St Louis Bus Stationbus bus
    22h 55m
    $173–289

Asheville to St. Louis by bus

Calendar7Weekly Buses
Duration19h 30mAverage Duration
Ticket$158Cheapest Price
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Questions & Answers

Map of how to get from Asheville to St. Louis.ExpandLaunch map view
  • Distance: 601.5 mi
  • Duration: 5h 26m

What companies run services between Asheville, NC, USA and St. Louis, MO, USA?

You can take a bus from Asheville, NC to St Louis Bus Station via Charlotte Bus Station and Atlanta Bus Station in around 19h 30m. Alternatively, Delta, American Airlines, and United Airlines fly from Asheville Regional Airport (AVL) to Lambert–St. Louis International Airport (STL) every 2 hours.

Airlines
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