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How to get fromAshland to St. Louisby plane, train, bus, bus (Greyhound), car, or train (Amtrak)

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There are 7 ways to get from Ashland to St. Louis by plane, train, bus, bus (Greyhound), car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Tri-State Airport

    best
    1. Fly from Tri-State Airport (HTS) to Lambert–St. Louis International Airport (STL)plane plane HTS - STL
    5h 20m
    $137–631

  2. Bus

    cheapest
    1. Take the bus from Ashland Bus Station to Columbusbus bus Greyhound US0140
    2. Take the bus from Columbus to St Louis Bus Stationbus bus Greyhound US0421
    12h 15m
    $72–166

  3. Train, bus

    1. Take the train from Ashland Amtrak Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    11h 56m
    $121–247

  4. Drive 448 mi

    1. Drive from Ashland to St. Louiscar car 448 mi
    7h 28m
    $82–119

  5. Train to Yeager Airport, fly

    1. Take the train from Ashland Amtrak Station to Charleston Stationtrain train
    2. Fly from Yeager Airport (CRW) to Lambert–St. Louis International Airport (STL)plane plane CRW - STL
    7h 59m
    $171–767

  6. Bus to John Glenn Columbus International Airport, fly

    1. Take the bus from Ashland Bus Station to Columbusbus bus
    2. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    6h 33m
    $816–984

  7. Train (Amtrak)

    1. Take the train from Ashland Amtrak Station to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    18h 17m
    $233–496

Ashland to St. Louis by train and bus

Calendar3Weekly Services
Duration11h 56mAverage Duration
Ticket$121Cheapest Price
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Questions & Answers

Map of how to get from Ashland to St. Louis.ExpandLaunch map view
  • Distance: 446.5 mi
  • Duration: 5h 20m

What companies run services between Ashland, KY, USA and St. Louis, MO, USA?

American Airlines flies from Tri-State Airport (HTS) to Lambert–St. Louis International Airport (STL) twice daily. Alternatively, you can take a bus from Ashland Bus Station to St Louis Bus Station via Columbus in around 12h 15m.

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