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How to get fromAthens to Knoxvilleby bus, plane, car, bus (Greyhound), or bus (Flixbus)

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There are 7 ways to get from Athens to Knoxville by bus, plane, car, bus (Greyhound), or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to John Glenn Columbus International Airport, fly to Mcghee Tyson Airport

    best
    1. Take the bus from Athens, Ohio OU Baker Center to John Glenn Columbus Intnl Airport (CMH)bus bus
    2. Fly from John Glenn Columbus International Airport (CMH) to Mcghee Tyson Airport (TYS)plane plane CMH - TYS
    6h 34m
    $234–1,010

  2. Drive 331.8 mi

    cheapest
    1. Drive from Athens to Knoxvillecar car 331.8 mi
    6h 55m
    $61–88

  3. Bus via Columbus

    1. Take the bus from Athens, Ohio OU Baker Center to Columbus, Ohio Greyhound Stationbus bus
    2. Take the bus from Columbus, OH to New York, NYbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    25h 10m
    $271–307

  4. Bus to John Glenn Columbus International Airport, fly to Nashville, drive

    1. Take the bus from Athens, Ohio OU Baker Center to John Glenn Columbus Intnl Airport (CMH)bus bus
    2. Fly from John Glenn Columbus International Airport (CMH) to Nashville (BNA)plane plane CMH - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    6h 54m
    $859–1,190

  5. Bus, bus to Yeager Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Athens, Ohio U Baker Center to Parkersburg, WV Marathon Stationbus bus
    2. Take the bus from Parkersburg, WV to Charleston, WVbus bus
    3. Fly from Yeager Airport (CRW) to Mcghee Tyson Airport (TYS)plane plane CRW - TYS
    8h 23m
    $209–1,011

  6. Bus

    1. Take the bus from Athens to Cambridgebus bus
    2. Take the bus from Cambridge, OH to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    29h 7m
    $274–427

  7. Bus via Charlie Haun WB Aft Washington PK

    1. Take the bus from Athens, Ohio OU Baker Center to Columbus, Ohio Greyhound Stationbus bus
    2. Take the bus from Columbus to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    32h 45m
    $220–312

John Glenn Columbus International Airport (CMH) to Mcghee Tyson Airport (TYS) flights

Calendar106Weekly Planes
Duration4h 27mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

Map of how to get from Athens to Knoxville.ExpandLaunch map view
  • Distance: 393.1 mi
  • Duration: 6h 34m

What companies run services between Athens, OH, USA and Knoxville, TN, USA?

You can take a bus from Athens, Ohio OU Baker Center to Knoxville via Columbus, Ohio Greyhound Station, Columbus, OH, New York, NY, and Knoxville, TN in around 25h 10m.

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