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How to get fromAtlanta to Florenceby bus (Greyhound), train (Amtrak), car, plane, bus, or train

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There are 7 ways to get from Atlanta to Florence by bus (Greyhound), train (Amtrak), car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus Greyhound US0642 / ...
    7h 5m
    $45–95

  2. Train (Amtrak)

    1. Take the train from Peachtree Station to Charlotte Amtrak Stationtrain train
    2. Take the train from Charlotte Amtrak Station to Selma Stationtrain train
    3. Take the train from Selma Station to Florence Stationtrain train
    14h 18m
    $189–397

  3. Drive 290.6 mi

    1. Drive from Atlanta to Florencecar car 290.6 mi
    4h 49m
    $53–77

  4. Fly to Myrtle Beach, bus

    1. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Myrtle Beach (MYR)plane plane ATL - MYR
    2. Take the bus from Myrtle Beach to Florencebus bus
    5h 15m
    $282–820

  5. Bus via Sumter

    1. Take the bus from Atlanta to Sumterbus bus Ses 975
    2. Take the bus from Sumter Bus Stop to Florence Bus Stationbus bus Greyhound US0645S
    7h 20m
    $91–126

  6. Fly to Fayetteville Municipal Airport, train

    1. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Fayetteville Municipal Airport (FAY)plane plane ATL - FAY
    2. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train
    5h 32m
    $104–446

  7. Fly to Charleston International Airport, train

    1. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Charleston International Airport (CHS)plane plane ATL - CHS
    2. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    7h 11m
    $366–1,072

Atlanta to Florence by bus

Calendar36Weekly Buses
Duration7h 5mAverage Duration
Ticket$45Cheapest Price
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Questions & Answers

Map of how to get from Atlanta to Florence.ExpandLaunch map view
  • Distance: 309.4 mi
  • Duration: 7h 5m

What companies run services between Atlanta, GA, USA and Florence, SC, USA?

Jefferson Lines operates a bus from Atlanta Bus Station to Florence Bus Station 3 times a day. Tickets cost $75–110 and the journey takes 7h 5m. Greyhound USA also services this route twice daily. Alternatively, you can take a train from Peachtree Station to Florence Station via Charlotte Amtrak Station and Selma Station in around 14h 18m.

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