There are 5 ways to get from Avignon Centre to Lyon by train (TGV, Trenitalia), bus, car, train, or rideshare
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Avignon Tgv
best- Take the train from Avignon Tgv to Lyon Part Dieutrain Tgv
1h 30m€28–71Rideshare
cheapest- Take the rideshare from Avignon to Lyon227.7 km
3h 9m€14Bus
- Take the bus from Avignon to Lyonbus FlixBus N1135 / ...
3h 59m€16–29Drive 225.3 km
- Drive from Avignon Centre to Lyoncar 225.3 km
2h 14m€36–52Train
- Take the train from Avignon Centre to Lyon Part Dieutrain Ter
2h 31m€35–85
Avignon Centre to Lyon by train
Comparing Your Travel Options
The cheapest way to get from Avignon Centre to Lyon is to rideshare which costs €14 and takes 3h 9m.
The fastest way to get from Avignon Centre to Lyon is to train via Avignon Tgv which takes 1h 30m and costs €27 - €75.
No, there is no direct bus from Avignon Centre to Lyon. However, there are services departing from Gare Centre and arriving at Lyon via Avignon. The journey, including transfers, takes approximately 3h 59m.
Yes, there is a direct train departing from Avignon Centre and arriving at Lyon Part Dieu. Services depart hourly, and operate every day. The journey takes approximately 2h 31m.
The distance between Avignon Centre and Lyon is 231 km. The road distance is 225.3 km.
The best way to get from Avignon Centre to Lyon without a car is to train via Avignon Tgv which takes 1h 30m and costs €27 - €75.
It takes approximately 1h 30m to get from Avignon Centre to Lyon, including transfers.
Avignon Centre to Lyon bus services, operated by FlixBus, depart from Avignon station.
Avignon Centre to Lyon train services, operated by TGV inOui, depart from Avignon Tgv station.
The best way to get from Avignon Centre to Lyon is to train via Avignon Tgv which takes 1h 30m and costs €27 - €75. Alternatively, you can bus, which costs €16 - €30 and takes 3h 59m.
What companies run services between Avignon Centre, France and Lyon, France?
TGV inOui operates a train from Avignon Tgv to Lyon Part Dieu hourly. Tickets cost €45–70 and the journey takes 1h 4m. Three other operators also service this route. Alternatively, FlixBus operates a bus from Avignon to Lyon 4 times a day. Tickets cost €18–28 and the journey takes 2h 40m. BlaBlaCar Bus also services this route 5 times a day.
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €45–70
- Website
- TGV inOui
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 6m
- Frequency
- 4 times a day
- Estimated price
- €35–70
- Website
- Oui.SNCF
Train from Avignon Centre to Lyon Part Dieu
- Ave. Duration
- 2h 31m
- Frequency
- Hourly
- Estimated price
- €35–70
- Website
- Oui.SNCF
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 8m
- Frequency
- Twice daily
- Estimated price
- €27–40
- Website
- Trenitalia
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 5m
- Frequency
- Twice a week
- Estimated price
- €40–65
- Website
- Belgian Railways
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Avignon Centre to Lyon Part Dieu
- Ave. Duration
- 2h 31m
- Frequency
- Every 3 hours
- Estimated price
- €60–85
- Website
- Zou! Lignes Express Régionales
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Avignon to Lyon
- Ave. Duration
- 2h 40m
- Frequency
- 4 times a day
- Estimated price
- €18–28
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Avignon to Lyon
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a day
- Estimated price
- €15–25
- Website
- BlaBlaCar Bus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar
Rideshare from Avignon to Lyon
- Ave. Duration
- 2h 59m
- Frequency
- Hourly
- Estimated price
- €14
- Schedules at
- BlaBlaCar
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Avignon Centre to Lyon bus services, operated by FlixBus, arrive at Lyon station.
Avignon Centre to Lyon train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
Yes, the driving distance between Avignon Centre to Lyon is 225 km. It takes approximately 2h 14m to drive from Avignon Centre to Lyon.
Book your Avignon Centre to Lyon train tickets online with Omio.
There are 3930+ hotels available in Lyon.
Check out Blablacar's carpooling service for rideshare options between Avignon Centre and Lyon. A great option if you don't have a driver's licence or want to avoid public transport.



























