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How to get fromAvignon to Karlsruheby train (TGV), bus, car, train, or plane

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There are 9 ways to get from Avignon to Karlsruhe by train (TGV), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Avignon Tgv to Strasbourgtrain train Tgv
    2. Take the train from Strasbourg to Karlsruhe Hbftrain train Ice / ...
    6h 7m
    €138–300

  2. Bus

    cheapest
    1. Take the bus from Avignon to Karlsruhe central train stationbus bus FlixBus N1135 / ...
    10h 50m
    €65–130

  3. Drive 760.8 km

    1. Drive from Avignon to Karlsruhecar car 760.8 km
    7h 32m
    €119–171

  4. Train to Marseille Provence Airport, fly to Strasbourg International Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Strasbourg International Airport (SXB)plane plane MRS - SXB
    3. Take the train from Strasbourg to Karlsruhe Hbftrain train
    4h 47m
    €91–332

  5. Train, bus

    1. Take the train from Avignon Centre to Annecytrain train K21
    2. Take the bus from Annecy - Bus Station to Karlsruhe - Central Station South Sidebus bus BlaBlaCar Bus
    14h 6m
    €136–258

  6. Train to Lyon–Saint Exupéry Airport, fly to Strasbourg International Airport, train

    1. Take the train from Avignon Tgv to Lyon-Saint Exupery Tgvtrain train
    2. Fly from Lyon–Saint Exupéry Airport (LYS) to Strasbourg International Airport (SXB)plane plane LYS - SXB
    3. Take the train from Strasbourg to Karlsruhe Hbftrain train
    4h 29m
    €151–414

  7. Train to Marseille Provence Airport, fly to Frankfurt, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Frankfurt (FRA)plane plane MRS - FRA
    3. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train
    6h 46m
    €111–339

  8. Train, train to Nice Côte D'Azur International Airport, fly to Strasbourg International Airport

    1. Take the train from Avignon Tgv to Marseille St Charlestrain train
    2. Take the train from Marseille-Saint-Charles to Nice-Saint-Augustintrain train
    3. Fly from Nice Côte D'Azur International Airport (NCE) to Strasbourg International Airport (SXB)plane plane NCE - SXB
    4. Take the train from Strasbourg to Karlsruhe Hbftrain train
    8h 1m
    €133–411

  9. Train to Marseille Provence Airport, fly to Zurich Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Zurich Airport (ZRH)plane plane MRS - ZRH
    3. Take the train from Zürich HB to Basel SBBtrain train
    4. Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain train
    8h 5m
    €155–501

Avignon to Karlsruhe by train

Calendar75Weekly Trains
Duration6h 7mAverage Duration
Ticket€138Cheapest Price
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Questions & Answers

Map of how to get from Avignon to Karlsruhe.ExpandLaunch map view
  • Distance: 804.1 km
  • Duration: 6h 7m

What companies run services between Avignon, France and Karlsruhe, Germany?

You can take a train from Avignon Tgv to Karlsruhe Hbf via Strasbourg in around 6h 7m. Alternatively, FlixBus operates a bus from Avignon to Karlsruhe central train station 3 times a day. Tickets cost €65–110 and the journey takes 10h 50m. BlaBlaCar Bus also services this route once daily.

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