There are 9 ways to get from Avignon to Karlsruhe by train (TGV), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (TGV)
best- Take the train from Avignon Tgv to Karlsruhe Hbftrain Tgv
6h 1m€160–260Bus
cheapest- Take the bus from Avignon to Karlsruhe central train stationbus FlixBus N1135 / ...
10h 50m€60–130Drive 760.8 km
- Drive from Avignon to Karlsruhecar 760.8 km
7h 32m€117–169Train to Marseille Provence Airport, fly to Strasbourg International Airport, train
- Take the train from Avignon Tgv to Aix En Provence Tgvtrain
- Fly from Marseille Provence Airport (MRS) to Strasbourg International Airport (SXB)plane MRS - SXB
- Take the train from Strasbourg to Karlsruhe Hbftrain
4h 43m€86–357Train, bus
- Take the train from Avignon Centre to Annecytrain K21
- Take the bus from Annecy - Bus Station to Karlsruhe - Central Station South Sidebus BlaBlaCar Bus
14h 6m€135–257Train to Lyon–Saint Exupéry Airport, fly to Strasbourg International Airport, train
- Take the train from Avignon Tgv to Lyon-Saint Exupery Tgvtrain
- Fly from Lyon–Saint Exupéry Airport (LYS) to Strasbourg International Airport (SXB)plane LYS - SXB
- Take the train from Strasbourg to Karlsruhe Hbftrain
4h 28m€141–419Train to Marseille Provence Airport, fly to Frankfurt, train
- Take the train from Avignon Tgv to Aix En Provence Tgvtrain
- Fly from Marseille Provence Airport (MRS) to Frankfurt (FRA)plane MRS - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
6h 43m€116–349Train, train to Nice Côte D'Azur International Airport, fly to Strasbourg International Airport
- Take the train from Avignon Tgv to Marseille St Charlestrain
- Take the train from Marseille-Saint-Charles to Nice-Saint-Augustintrain
- Fly from Nice Côte D'Azur International Airport (NCE) to Strasbourg International Airport (SXB)plane NCE - SXB
- Take the train from Strasbourg to Karlsruhe Hbftrain
7h 56m€128–436Train to Marseille Provence Airport, fly to Zurich Airport, train
- Take the train from Avignon Tgv to Aix En Provence Tgvtrain
- Fly from Marseille Provence Airport (MRS) to Zurich Airport (ZRH)plane MRS - ZRH
- Take the train from Zürich HB to Basel SBBtrain
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain
8h 2m€155–515
Avignon to Karlsruhe by train (TGV)
Questions & Answers
The cheapest way to get from Avignon to Karlsruhe is to bus which costs €60 - €130 and takes 10h 50m.
The fastest way to get from Avignon to Karlsruhe is to train and fly which takes 4h 28m and costs €140 - €420.
Yes, there is a direct bus departing from Avignon and arriving at Karlsruhe central train station station. Services depart four times a day, and operate every day. The journey takes approximately 10h 50m.
Yes, there is a direct train departing from Avignon Tgv and arriving at Karlsruhe Hbf. Services depart twice daily, and operate every day. The journey takes approximately 6h 1m.
The distance between Avignon and Karlsruhe is 808 km. The road distance is 760.8 km.
The best way to get from Avignon to Karlsruhe without a car is to train which takes 6h 1m and costs €160 - €260.
The train from Avignon Tgv to Karlsruhe Hbf takes 6h 1m including transfers and departs twice daily.
Avignon to Karlsruhe bus services, operated by FlixBus, depart from Avignon station.
Avignon to Karlsruhe train services, operated by TGV inOui, depart from Avignon Tgv station.
The best way to get from Avignon to Karlsruhe is to train which takes 6h 1m and costs €160 - €260. Alternatively, you can bus, which costs €60 - €130 and takes 10h 50m.
What companies run services between Avignon, France and Karlsruhe, Germany?
TGV inOui operates a train from Avignon Tgv to Karlsruhe Hbf twice daily. Tickets cost €160–260 and the journey takes 6h 1m. Alternatively, FlixBus operates a bus from Avignon to Karlsruhe central train station 3 times a day. Tickets cost €60–110 and the journey takes 10h 50m. BlaBlaCar Bus also services this route twice daily.
- Website
- lufthansa.com
Flights from Marseille Provence Airport to Strasbourg International Airport via Frankfurt
- Ave. Duration
- 3h 30m
- When
- Monday
- Estimated price
- €70–410
Flights from Marseille Provence Airport to Frankfurt
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €40–260
Flights from Marseille Provence Airport to Zurich Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €90–300
Flights from Marseille Provence Airport to Zurich Airport via Frankfurt
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €55–320
- Website
- volotea.com
Flights from Marseille Provence Airport to Strasbourg International Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Friday, Wednesday, and Thursday
- Estimated price
- €45–230
Flights from Nice Côte D'Azur International Airport to Strasbourg International Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €35–170
- Website
- twinjet.fr
Flights from Lyon–Saint Exupéry Airport to Strasbourg International Airport
- Ave. Duration
- 1h 10m
- When
- Monday to Thursday
- Estimated price
- €750–1,100
- Website
- lufthansa-city.com
Flights from Marseille Provence Airport to Frankfurt
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €40–260
- Website
- swiss.com
Flights from Marseille Provence Airport to Zurich Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €90–300
- Website
- easyjet.com
Flights from Nice Côte D'Azur International Airport to Strasbourg International Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €45–250
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Avignon Tgv to Karlsruhe Hbf
- Ave. Duration
- 6h 1m
- Frequency
- Twice daily
- Estimated price
- €160–260
- Website
- TGV inOui
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 19 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–24
- Website
- TGV inOui
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 41 min
- Frequency
- Every 2 hours
- Estimated price
- €16–26
- Website
- TGV inOui
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 41 min
- Frequency
- Every 2 hours
- Estimated price
- €16–26
- Website
- TGV inOui
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 19 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–24
- Website
- TGV inOui
Train from Avignon Tgv to Marseille St Charles
- Ave. Duration
- 35 min
- Frequency
- Every 30 minutes
- Estimated price
- €18–30
- Website
- TGV inOui
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 41 min
- Frequency
- Every 2 hours
- Estimated price
- €16–26
- Website
- TGV inOui
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 19 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–24
- Website
- TGV inOui
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 22 min
- Frequency
- Every 3 hours
- Estimated price
- €12–25
- Website
- Oui.SNCF
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 52 min
- Frequency
- Twice a week
- Estimated price
- €13–27
- Website
- Oui.SNCF
Train from Avignon Tgv to Lyon-Saint Exupery Tgv
- Ave. Duration
- 51 min
- Frequency
- Every 3 hours
- Estimated price
- €35–75
- Website
- Oui.SNCF
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 52 min
- Frequency
- Twice a week
- Estimated price
- €13–27
- Website
- Oui.SNCF
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 22 min
- Frequency
- Every 3 hours
- Estimated price
- €12–25
- Website
- Oui.SNCF
Train from Avignon Tgv to Marseille St Charles
- Ave. Duration
- 2h 9m
- Frequency
- Hourly
- Estimated price
- €15–35
- Website
- Oui.SNCF
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 52 min
- Frequency
- Twice a week
- Estimated price
- €13–27
- Website
- Oui.SNCF
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 22 min
- Frequency
- Every 3 hours
- Estimated price
- €12–25
- Website
- Oui.SNCF
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 20 min
- Frequency
- Every 4 hours
- Estimated price
- €9–15
- Website
- Trenitalia
Train from Avignon Tgv to Lyon-Saint Exupery Tgv
- Ave. Duration
- 50 min
- Frequency
- 5 times a day
- Estimated price
- €27–45
- Website
- Trenitalia
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 20 min
- Frequency
- Every 4 hours
- Estimated price
- €9–15
- Website
- Trenitalia
Train from Avignon Tgv to Marseille St Charles
- Ave. Duration
- 35 min
- Frequency
- Every 4 hours
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 20 min
- Frequency
- Every 4 hours
- Estimated price
- €9–15
- Website
- Trenitalia
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 19 min
- Frequency
- 4 times a day
- Estimated price
- €9–15
- Website
- Renfe Viajeros
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 19 min
- Frequency
- 4 times a day
- Estimated price
- €9–15
- Website
- Renfe Viajeros
Train from Avignon Tgv to Marseille St Charles
- Ave. Duration
- 37 min
- Frequency
- 4 times a day
- Estimated price
- €11–18
- Website
- Renfe Viajeros
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 19 min
- Frequency
- 4 times a day
- Estimated price
- €9–15
- Website
- Renfe Viajeros
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 39 min
- Frequency
- Every 2 hours
- Estimated price
- €14–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 39 min
- Frequency
- Every 2 hours
- Estimated price
- €14–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 4 hours
- Estimated price
- €24–110
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 39 min
- Frequency
- Every 2 hours
- Estimated price
- €14–65
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €35–160
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Avignon Centre to Annecy
- Ave. Duration
- 4h 16m
- Frequency
- Once a week
- Estimated price
- €85–180
- Website
- Zou! Lignes Express Régionales
Train from Avignon Tgv to Marseille St Charles
- Ave. Duration
- 2h 9m
- Frequency
- Once daily
- Estimated price
- €24–50
- Website
- Zou! Lignes Express Régionales
Train from Marseille-Saint-Charles to Nice-Saint-Augustin
- Ave. Duration
- 2h 32m
- Frequency
- Hourly
- Estimated price
- €55–110
- Website
- Zou! Lignes Express Régionales
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 53m
- Frequency
- Once daily
- Estimated price
- €14–30
- Website
- Nederlandse Spoorwegen (NS)
Train from Zürich HB to Basel SBB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €30–95
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Avignon to Karlsruhe central train station
- Ave. Duration
- 10h 50m
- Frequency
- 3 times a day
- Estimated price
- €60–110
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Avignon to Karlsruhe central train station
- Ave. Duration
- 11h
- Frequency
- Twice daily
- Estimated price
- €65–130
- Website
- BlaBlaCar Bus
Bus from Annecy - Bus Station to Karlsruhe - Central Station South Side
- Ave. Duration
- 8h 50m
- Frequency
- Once daily
- Estimated price
- €45–85
- Website
- BlaBlaCar Bus
Want to know more about travelling around Germany
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Want to know more about Flixbus?
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Train travel in France: A guide to SNCF
Read the travel guide
More Questions & Answers
Avignon to Karlsruhe bus services, operated by FlixBus, arrive at Karlsruhe central train station.
Avignon to Karlsruhe train services, operated by TGV inOui, arrive at Karlsruhe Hbf station.
Yes, the driving distance between Avignon to Karlsruhe is 761 km. It takes approximately 7h 32m to drive from Avignon to Karlsruhe.
Book your Avignon to Karlsruhe train tickets online with Omio.
Book your Avignon to Karlsruhe bus tickets online with Omio and FlixBus.
There are 889+ hotels available in Karlsruhe.









































