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How to get fromAvignon to Sienaby train (TGV, Trenitalia), bus, ferry, car, train, or plane

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There are 10 ways to get from Avignon to Siena by train (TGV, Trenitalia), bus, ferry, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Avignon Tgv to Lyon Part Dieutrain train Tgv
    2. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    11h 45m
    €118–233

  2. Bus

    cheapest
    1. Take the bus from Avignon - Le Pontet - Le Lac Stop to Marseille - Saint-Charles Bus Stationbus bus
    2. Take the bus from Marseille, Gare de Marseille-Saint-Charles to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    13h 5m
    €67–105

  3. Bus, ferry

    1. Take the bus from Limbert/Remparts to La Beauvallebus bus 63
    2. Take the bus from La Beauvalle to Gare Routièrebus bus 59
    3. Take the ferry from Port of Toulon to Port of Bastiaferry ferry
    4. Take the ferry from Port of Bastia to Port of Piombinoferry ferry
    5. Take the bus from Port of Piombino to Siena-Via Tozzibus bus
    24h 29m

  4. Drive  712.8 km

    1. Drive from Avignon to Sienacar car 712.8 km
    7h 55m
    €116–167

  5. Train via Ventimiglia

    1. Take the train from Avignon Tgv to Nice Villetrain train Tgv
    2. Take the train from Ventimiglia to Pisa Centraletrain train Ic
    3. Take the train from Pisa Centrale to Empolitrain train Re
    4. Take the train from Empoli to Sienatrain train Re
    12h
    €114–184

  6. Train to Marseille Provence Airport, fly to Florence Peretola Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Florence Peretola Airport (FLR)plane plane MRS - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h 51m
    €110–275

  7. Train to Marseille Provence Airport, fly to Bastia - Poretta Airport, ferry, bus

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Bastia - Poretta Airport (BIA)plane plane MRS - BIA
    3. Take the ferry from Port of Bastia to Port of Piombinoferry ferry
    4. Take the bus from Port of Piombino to Colonna San Marcobus bus
    11h 27m
    €141–383

  8. Train, train to Nice Côte D'Azur International Airport, fly to Florence Peretola Airport

    1. Take the train from Avignon Tgv to Marseille St Charlestrain train
    2. Take the train from Marseille St Charles to Antibestrain train
    3. Fly from Nice Côte D'Azur International Airport (NCE) to Florence Peretola Airport (FLR)plane plane NCE - FLR
    4. Take the train from Firenze S.M.N. to Sienatrain train
    10h 28m
    €157–345

  9. Train to Marseille Provence Airport, fly to Roma Ciampino Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Roma Ciampino Airport (CIA)plane plane MRS - CIA
    3. Take the train from Roma Termini to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    9h 26m
    €163–573

  10. Train to Marseille Provence Airport, fly to Fiumicino International Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Fiumicino International Airport (FCO)plane plane MRS - FCO
    3. Take the train from Roma Termini to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    9h 17m
    €104–304

Avignon to Siena by train

Calendar14Weekly Trains
Duration11h 45mAverage Duration
Ticket€118Cheapest Price
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Comparing Your Travel Options

Map of how to get from Avignon to Siena.ExpandLaunch map view
  • Distance: 1,068.6 km
  • Duration: 11h 45m

What companies run services between Avignon, France and Siena, Italy?

You can take a train from Avignon Tgv to Siena via Lyon Part Dieu, Milano Centrale, and Firenze S.M.N. in around 11h 45m. Alternatively, you can take a bus from Avignon - Le Pontet - Le Lac Stop to Siena via Marseille, Gare de Marseille-Saint-Charles and Florence Villa Constanza Bus Station in around 13h 5m.

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