There are 7 ways to get from Avignon to Syracuse by train, plane, bus, ferry, night train, train (TGV, Trenitalia), car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, fly, bus
best- Take the train from Avignon Tgv to Aix En Provence Tgvtrain
- Fly from Marseille Provence Airport (MRS) to Catania–Fontanarossa Airport (CTA)plane MRS - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
6h 5m€69–285Train, ferry
- Take the train from Avignon Tgv to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Siracusatrain Re
22h 4mBus
- Take the bus from Avignon - Le Pontet - Le Lac Stop to Marseille - Saint-Charles Bus Stationbus
- Take the bus from Marseille, Gare de Marseille-Saint-Charles to Roma, Autostazione Tiburtinabus
- Take the bus from Roma, Autostazione Tiburtina to Catania Via D'Amicobus
- Take the bus from Catania Via Archimede to Siracusa - Von Platenbus
27h 31m€114–189Train, night train
- Take the train from Avignon Tgv to Nice Villetrain Tgv
- Take the train from Ventimiglia to Milano Centraletrain Ic
- Take the nighttrain from Milano Centrale to Siracusanighttrain Ini
29h 23m€221–368Train
- Take the train from Avignon Tgv to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Roma Terminitrain
- Take the train from Roma Termini to Siracusatrain Ic
22h 33m€227–411Train, bus
- Take the train from Avignon Centre to Valence Villetrain Ter
- Take the train from Valence Ville to Chambery Challes Les Eauxtrain Ter
- Take the bus from Chambery Central Bus Station to Turin Stura Bus Stationbus
- Take the bus from Turin Stura Bus Station to Catania Fontanarossa Airport Bus Stopbus
- Take the bus from Catania Airport to Siracusa - Von Platenbus
34h 4m€143–282Drive, car ferry
- Drive from Avignon to Villa S. Giovannicar
- Take the carferry from Villa S. Giovanni to Tresmestiericarferry
- Drive from Tresmestieri to Syracusecar
17h 38m€303–446
Marseille Provence Airport (MRS) to Catania–Fontanarossa Airport (CTA) flights
Comparing Your Travel Options
The cheapest way to get from Avignon to Syracuse is to train and fly and bus which costs €65 - €290 and takes 6h 5m.
The fastest way to get from Avignon to Syracuse is to train and fly and bus which takes 6h 5m and costs €65 - €290.
No, there is no direct bus from Avignon to Syracuse. However, there are services departing from Avignon - Le Pontet - Le Lac Stop and arriving at Siracusa - Von Platen via Marseille, Gare de Marseille-Saint-Charles, Roma, Autostazione Tiburtina and Catania Via Archimede. The journey, including transfers, takes approximately 27h 31m.
No, there is no direct train from Avignon to Syracuse. However, there are services departing from Avignon Tgv and arriving at Siracusa via Nice-Ville, Ventimiglia and Milano Centrale. The journey, including transfers, takes approximately 29h 23m.
The distance between Avignon and Syracuse is 1208 km.
The best way to get from Avignon to Syracuse without a car is to train and ferry which takes 22h 4m and costs .
It takes approximately 6h 5m to get from Avignon to Syracuse, including transfers.
Avignon to Syracuse bus services, operated by BlaBlaCar Bus, depart from Avignon - Le Pontet - Le Lac Stop station.
Avignon to Syracuse train services, operated by TGV inOui, depart from Avignon Tgv station.
The best way to get from Avignon to Syracuse is to bus which takes 27h 31m and costs €110 - €190. Alternatively, you can train, which costs €220 - €420 and takes 22h 33m.
What companies run services between Avignon, France and Syracuse, Italy?
You can take a bus from Avignon - Le Pontet - Le Lac Stop to Siracusa - Von Platen via Marseille, Gare de Marseille-Saint-Charles, Roma, Autostazione Tiburtina, Catania Via D'Amico, and Catania Via Archimede in around 27h 31m. Alternatively, you can take a train from Avignon Tgv to Siracusa via Lyon Part Dieu, Milano Centrale, and Roma Termini in around 22h 33m.
- Website
- ryanair.com
Flights from Marseille Provence Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 55m
- When
- Tuesday, Friday, and Sunday
- Estimated price
- €50–230
Flights from Marseille Provence Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 18m
- When
- Wednesday, Sunday, Saturday, and Thursday
- Estimated price
- €50–230
Flights from Marseille Provence Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 4h 45m
- When
- Thursday
- Estimated price
- €50–230
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 21 min
- Frequency
- Every 30 minutes
- Estimated price
- €14–22
- Website
- TGV inOui
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €40–65
- Website
- TGV inOui
Train from Avignon Tgv to Nice Ville
- Ave. Duration
- 3h 2m
- Frequency
- Every 4 hours
- Estimated price
- €60–90
- Website
- TGV inOui
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €40–65
- Website
- TGV inOui
Train from Avignon Centre to Valence Ville
- Ave. Duration
- 1h 6m
- Frequency
- 4 times a day
- Estimated price
- €24–40
- Website
- TGV inOui
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 22 min
- Frequency
- Hourly
- Estimated price
- €12–22
- Website
- Oui.SNCF
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 6m
- Frequency
- 4 times a day
- Estimated price
- €35–70
- Website
- Oui.SNCF
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 6m
- Frequency
- 4 times a day
- Estimated price
- €35–70
- Website
- Oui.SNCF
Train from Avignon Centre to Valence Ville
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- €21–40
- Website
- Oui.SNCF
Train from Valence Ville to Chambery Challes Les Eaux
- Ave. Duration
- 2h 5m
- Frequency
- Hourly
- Estimated price
- €28–50
- Website
- Oui.SNCF
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 20 min
- Frequency
- Every 4 hours
- Estimated price
- €8–13
- Website
- Trenitalia
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 8m
- Frequency
- Twice daily
- Estimated price
- €27–40
- Website
- Trenitalia
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- 4 times a day
- Estimated price
- €35–50
- Website
- Trenitalia
Train from Messina Centrale to Siracusa
- Ave. Duration
- 2h 45m
- Frequency
- 5 times a day
- Estimated price
- €21–29
- Website
- Trenitalia
Train from Ventimiglia to Milano Centrale
- Ave. Duration
- 4h 30m
- Frequency
- Twice daily
- Estimated price
- €30–50
- Website
- Trenitalia
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 8m
- Frequency
- Twice daily
- Estimated price
- €27–40
- Website
- Trenitalia
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- 4 times a day
- Estimated price
- €50–75
- Website
- Trenitalia
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 19 min
- Frequency
- 4 times a day
- Estimated price
- €9–14
- Website
- Renfe Viajeros
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 5m
- Frequency
- Twice a week
- Estimated price
- €35–65
- Website
- Belgian Railways
Train from Avignon Tgv to Lyon Part Dieu
- Ave. Duration
- 1h 5m
- Frequency
- Twice a week
- Estimated price
- €35–65
- Website
- Belgian Railways
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Torino Porta Susa to Villa S.Giovanni
- Ave. Duration
- 10h 30m
- Frequency
- 5 times a day
- Estimated price
- €180–320
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Torino Porta Susa to Villa S.Giovanni
- Ave. Duration
- 11h 37m
- Frequency
- Once daily
- Estimated price
- €160–260
- Website
- Italo Treno
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Hourly
- Estimated price
- €65–110
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Messina Centrale to Siracusa
- Ave. Duration
- 2h 40m
- Frequency
- 6 times a week
- Estimated price
- €18–35
- Website
- Trenitalia Intercity
Train from Ventimiglia to Milano Centrale
- Ave. Duration
- 3h 50m
- Frequency
- Every 2 hours
- Estimated price
- €30–55
- Website
- Trenitalia Intercity
Train from Roma Termini to Siracusa
- Ave. Duration
- 11h 12m
- Frequency
- 3 times a week
- Estimated price
- €85–160
- Website
- Trenitalia Intercity
- Phone
- 06 3000
- Website
- Trenitalia ICN
Night train from Milano Centrale to Siracusa
- Ave. Duration
- 19h 38m
- Frequency
- 3 times a week
- Estimated price
- €120–210
- Website
- Trenitalia ICN
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Avignon Centre to Valence Ville
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- €30–45
- Website
- Zou! Lignes Express Régionales
Train from Valence Ville to Chambery Challes Les Eaux
- Ave. Duration
- 2h 2m
- Frequency
- Every 2 hours
- Estimated price
- €40–60
- Website
- Zou! Lignes Express Régionales
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - Von Platen
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €3–9
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - Von Platen
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Avignon - Le Pontet - Le Lac Stop to Marseille - Saint-Charles Bus Station
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- €6–11
- Website
- BlaBlaCar Bus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Marseille, Gare de Marseille-Saint-Charles to Roma, Autostazione Tiburtina
- Ave. Duration
- 12h 45m
- Frequency
- Once daily
- Estimated price
- €75–120
- Website
- Flixbus
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Roma, Autostazione Tiburtina to Catania Via D'Amico
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- €30–50
- Schedules at
- autoservizisalemi.it
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Chambery Central Bus Station to Turin Stura Bus Station
- Ave. Duration
- 3h 44m
- Frequency
- Twice daily
- Estimated price
- €11–20
- Website
- Itabus S.p.A.
Bus from Turin Stura Bus Station to Catania Fontanarossa Airport Bus Stop
- Ave. Duration
- 23h 5m
- Frequency
- Twice daily
- Estimated price
- €80–150
- Website
- Itabus S.p.A.
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
- Phone
- 090774409
- [email protected]
- Website
- bluferries.it
Car ferry from Villa S. Giovanni to Tresmestieri
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Train travel in France: A guide to SNCF
Read the travel guide
Booking & Getting There
Avignon to Syracuse bus services, operated by BlaBlaCar Bus, arrive at Marseille - Saint-Charles Bus Station.
Avignon to Syracuse train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
Book your Avignon to Syracuse train tickets online with Omio.
Book your Avignon to Syracuse bus tickets online with Omio.
There are 3091+ hotels available in Syracuse.






























































