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How to get fromBaltimore to Buffalo Depew Stationby plane, train (Amtrak), bus (Flixbus, Greyhound), car, train, subway, or bus (Greyhound)

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There are 8 ways to get from Baltimore to Buffalo Depew Station by plane, train (Amtrak), bus (Flixbus, Greyhound), car, train, subway, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Baltimore-Washington International Airport

    best
    1. Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane plane BWI - BUF
    2h 49m
    $103–616

  2. Drive 350.3 mi

    cheapest
    1. Drive from Baltimore to Buffalo Depew Stationcar car 350.3 mi
    6h 58m
    $64–93

  3. Train (Amtrak)

    1. Take the train from Baltimore Penn Station to Ny Moynihan Train Hall At Penn Stationtrain train Acela
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalo Depew Stationtrain train Empire Service / ...
    11h 29m
    $200–410

  4. Bus via Newark

    1. Take the bus from Baltimore Downtown Bus Station to Newark Penn Stationbus bus Greyhound US0310 / ...
    2. Take the bus from Newark Penn Station to Buffalobus bus FlixBus 2686 / ...
    14h 3m
    $93–178

  5. Train to Ronald Reagan Washington National Airport, fly

    1. Take the train from Baltimore Penn Station to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Buffalo Niagara International Airport (BUF)plane plane DCA - BUF
    3h 54m
    $147–1,425

  6. Train, subway to Washington Dulles International Airport, fly

    1. Take the train from Baltimore Penn Station to New Carrollton Amtrak Stationtrain train
    2. Take the subway from New Carrollton, Orange Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Buffalo Niagara International Airport (BUF)plane plane IAD - BUF
    4h 48m
    $90–526

  7. Train to Philadelphia International Airport, fly

    1. Take the train from Baltimore Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane plane PHL - BUF
    4h 27m
    $146–1,316

  8. Bus

    1. Take the bus from Baltimore Greyhound Garage to Harrisburg Bus Stationbus bus
    2. Take the bus from Harrisburg, Pa to Dubois, Pabus bus 731
    3. Take the bus from DuBois to Buffalobus bus
    18h 46m
    $85–249

Baltimore to Buffalo Depew Station by train (Amtrak)

Calendar28Weekly Trains
Duration11h 29mAverage Duration
Ticket$200Cheapest Price
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Questions & Answers

Map of how to get from Baltimore to Buffalo Depew Station.ExpandLaunch map view
  • Distance: 292.5 mi
  • Duration: 2h 49m

What companies run services between Baltimore, MD, USA and Buffalo Depew Station, NY, USA?

Southwest Airlines flies from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF) 4 times a day. Alternatively, you can take a train from Baltimore Penn Station to Buffalo Depew Station via Ny Moynihan Train Hall At Penn Station in around 11h 29m.

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