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How to get fromBaltimore to Florenceby plane, bus, bus (Greyhound, Flixbus), train (Amtrak), car, or train

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There are 9 ways to get from Baltimore to Florence by plane, bus, bus (Greyhound, Flixbus), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Baltimore-Washington International Airport to Myrtle Beach, bus

    best
    1. Fly from Baltimore-Washington International Airport (BWI) to Myrtle Beach (MYR)plane plane BWI - MYR
    2. Take the bus from Myrtle Beach to Florencebus bus
    5h 46m
    $292–720

  2. Bus

    cheapest
    1. Take the bus from Baltimore Downtown Bus Station to Raleigh Bus Stationbus bus Greyhound US0700 / ...
    2. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus Greyhound US0642 / ...
    9h 55m
    $72–140

  3. Train (Amtrak)

    1. Take the train from Baltimore Penn Station to Florence Stationtrain train Palmetto / ...
    11h 51m
    $140–300

  4. Drive 437.7 mi

    1. Drive from Baltimore to Florencecar car 437.7 mi
    7h 35m
    $80–116

  5. Train to Ronald Reagan Washington National Airport, fly to Myrtle Beach, bus

    1. Take the train from Baltimore Penn Station to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Myrtle Beach (MYR)plane plane DCA - MYR
    3. Take the bus from Myrtle Beach to Florencebus bus
    6h 57m
    $131–1,099

  6. Fly Baltimore-Washington International Airport to Charleston International Airport, train

    1. Fly from Baltimore-Washington International Airport (BWI) to Charleston International Airport (CHS)plane plane BWI - CHS
    2. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    7h 59m
    $416–1,271

  7. Fly Baltimore-Washington International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Baltimore-Washington International Airport (BWI) to Charlotte Douglas International Airport (CLT)plane plane BWI - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    8h 26m
    $136–397

  8. Fly Baltimore-Washington International Airport to Raleigh-Durham International Airport, bus

    1. Fly from Baltimore-Washington International Airport (BWI) to Raleigh-Durham International Airport (RDU)plane plane BWI - RDU
    2. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    8h 30m
    $211–447

  9. Bus, train

    1. Take the bus from Baltimore Downtown Bus Station to Fayetteville Bus Stationbus bus FlixBus N2471 / ...
    2. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train Palmetto / ...
    10h 11m
    $85–150

Baltimore to Florence by bus

Calendar22Weekly Buses
Duration9h 55mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

Map of how to get from Baltimore to Florence.ExpandLaunch map view
  • Distance: 487.6 mi
  • Duration: 5h 46m

What companies run services between Baltimore, MD, USA and Florence, SC, USA?

You can take a bus from Baltimore Downtown Bus Station to Florence Bus Station via Raleigh Bus Station in around 9h 55m. Alternatively, Amtrak operates a train from Baltimore Penn Station to Florence Station twice daily. Tickets cost $140–300 and the journey takes 11h 51m.

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Bus operators

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