Rome2Rio

How to get fromBeaufort to Louisvilleby car, plane, bus, or taxi

Find Transport to Louisville

See all options

There are 6 ways to get from Beaufort to Louisville by car, plane, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Charleston International Airport, fly

    best
    1. Drive from Beaufort to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Louisville International Airport (SDF)plane plane CHS - SDF
    4h 33m
    $144–821

  2. Drive  600.1 mi

    cheapest
    1. Drive from Beaufort to Louisvillecar car 600.1 mi
    11h 50m
    $106–154

  3. Drive, bus

    1. Drive from Beaufort to Charleston Bus Stationcar car
    2. Take the bus from Charleston Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    4. Take the bus from Nashville to Louisville, KYbus bus
    22h 37m
    $163–268

  4. Taxi to Savannah, fly

    1. Take the taxi from Beaufort to Savannah (SAV)taxi taxi
    2. Fly from Savannah (SAV) to Louisville International Airport (SDF)plane plane SAV - SDF
    5h 37m
    $341–1,077

  5. Taxi to Hilton Head Airport, fly

    1. Take the taxi from Beaufort to Hilton Head Airport (HHH)taxi taxi
    2. Fly from Hilton Head Airport (HHH) to Louisville International Airport (SDF)plane plane HHH - SDF
    5h 58m
    $213–812

  6. Drive, bus via Preston @ Vim

    1. Drive from Beaufort to Charleston Bus Stationcar car
    2. Take the bus from Charleston Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    4. Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus bus
    23h 29m
    $171–283

Charleston International Airport (CHS) to Louisville International Airport (SDF) flights

Calendar59Weekly Planes
Duration3h 58mAverage Duration
Ticket$131Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Beaufort to Louisville.ExpandLaunch map view
  • Distance: 563.5 mi
  • Duration: 4h 33m

What companies run services between Beaufort, SC, USA and Louisville, KY, USA?

There is no direct connection from Beaufort to Louisville. However, you can drive to Charleston-Airport-CHS airport, fly to Louisville International Airport (SDF), walk to Louisville International Airport, then take the line 02 bus to 2nd @ York. Alternatively, you can take a vehicle from Beaufort to Louisville, KY via Charleston Bus Station, Atlanta Bus Station, and Nashville in around 22h 37m.

Airlines
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound