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How to get fromBethesda to Florenceby train (Amtrak), bus (Greyhound, Flixbus), car, plane, bus, bus (Flixbus), subway, or train

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There are 11 ways to get from Bethesda to Florence by train (Amtrak), bus (Greyhound, Flixbus), car, plane, bus, bus (Flixbus), subway, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Washington Union Station to Florence Stationtrain train Palmetto / ...
    9h 9m
    $132–272

  2. Bus via Raleigh

    cheapest
    1. Take the bus from Washington Union Station to Raleigh Bus Stationbus bus Greyhound US0700 / ...
    2. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus Greyhound US0642S / ...
    10h 26m
    $65–122

  3. Drive 404.8 mi

    1. Drive from Bethesda to Florencecar car 404.8 mi
    6h 59m
    $74–107

  4. Fly Ronald Reagan Washington National Airport to Charlotte Douglas International Airport, bus

    1. Fly from Ronald Reagan Washington National Airport (DCA) to Charlotte Douglas International Airport (CLT)plane plane DCA - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    8h 24m
    $148–850

  5. Bus

    1. Take the bus from Bethesda to Richmondbus bus FlixBus 2605
    2. Take the bus from Richmond - Brook + Walmart Nhood Mkt to Florence, SCbus bus Nyc
    11h 20m
    $70–108

  6. Fly Ronald Reagan Washington National Airport to Raleigh-Durham International Airport, bus

    1. Fly from Ronald Reagan Washington National Airport (DCA) to Raleigh-Durham International Airport (RDU)plane plane DCA - RDU
    2. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    8h 49m
    $583–1,256

  7. Fly Ronald Reagan Washington National Airport to Columbia, bus

    1. Fly from Ronald Reagan Washington National Airport (DCA) to Columbia (CAE)plane plane DCA - CAE
    2. Take the bus from Columbia, SC to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    9h 12m
    $274–1,465

  8. Subway to Washington Dulles International Airport, fly to Columbia, bus

    1. Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    2. Fly from Washington Dulles International Airport (IAD) to Columbia (CAE)plane plane IAD - CAE
    3. Take the bus from Columbia, SC to Camdenbus bus
    4. Take the bus from Camden to Florence Bus Stationbus bus
    9h 39m
    $183–914

  9. Fly Ronald Reagan Washington National Airport to Myrtle Beach, bus, train

    1. Fly from Ronald Reagan Washington National Airport (DCA) to Myrtle Beach (MYR)plane plane DCA - MYR
    2. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    3. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    9h 18m
    $136–584

  10. Train to Baltimore-Washington International Airport, fly to Myrtle Beach, bus, train

    1. Take the train from Washington Union Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Myrtle Beach (MYR)plane plane BWI - MYR
    3. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    4. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    9h 40m
    $300–1,310

  11. Subway to Washington Dulles International Airport, fly to Myrtle Beach, bus, train

    1. Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    2. Fly from Washington Dulles International Airport (IAD) to Myrtle Beach (MYR)plane plane IAD - MYR
    3. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    4. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    11h 36m
    $410–1,513

Bethesda to Florence by subway and train (Amtrak)

Calendar14Weekly Services
Duration9h 9mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

Map of how to get from Bethesda to Florence.ExpandLaunch map view
  • Distance: 416.3 mi
  • Duration: 9h 9m

What companies run services between Bethesda, MD, USA and Florence, SC, USA?

Amtrak operates a train from Washington Union Station to Florence Station twice daily. Tickets cost $130–270 and the journey takes 7h 48m. Alternatively, you can take a bus from Wisconsin Av NW+Albemarle St NW to Florence Bus Station via Massachusetts Av NE+1 St NE, Washington Union Station, and Raleigh Bus Station in around 10h 26m.

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