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How to get fromBethesda to Knoxvilleby plane, train, bus, car, subway, bus (Greyhound), or bus (Flixbus)

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There are 8 ways to get from Bethesda to Knoxville by plane, train, bus, car, subway, bus (Greyhound), or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ronald Reagan Washington National Airport to Mcghee Tyson Airport

    best
    1. Fly from Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS)plane plane DCA - TYS
    3h 44m
    $289–1,476

  2. Drive  474.5 mi

    cheapest
    1. Drive from Bethesda to Knoxvillecar car 474.5 mi
    8h 18m
    $82–118

  3. Train, bus

    1. Take the train from Washington Union Station to Ny Moynihan Train Hall At Penn Stationtrain train Acela
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    17h 17m
    $260–355

  4. Subway to Washington Dulles International Airport, fly to Mcghee Tyson Airport

    1. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    2. Fly from Washington Dulles International Airport (IAD) to Mcghee Tyson Airport (TYS)plane plane IAD - TYS
    4h 6m
    $209–1,025

  5. Train to Baltimore-Washington International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Washington Union Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Mcghee Tyson Airport (TYS)plane plane BWI - TYS
    4h 17m
    $239–1,722

  6. Fly Ronald Reagan Washington National Airport to Asheville Regional Airport, drive

    1. Fly from Ronald Reagan Washington National Airport (DCA) to Asheville Regional Airport (AVL)plane plane DCA - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    5h 29m
    $109–586

  7. Bus via Farragut

    1. Take the bus from Washington Union Station to Port Authority Bus Terminalbus bus Greyhound US0670 / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    19h 6m
    $235–330

  8. Bus

    1. Take the bus from Bethesda to New York City Chinatownbus bus FlixBus 2605
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    22h 15m
    $144–181

Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS) flights

Calendar68Weekly Planes
Duration3h 25mAverage Duration
Ticket$232Cheapest Price
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Comparing Your Travel Options

Map of how to get from Bethesda to Knoxville.ExpandLaunch map view
  • Distance: 461.6 mi
  • Duration: 3h 44m

What companies run services between Bethesda, MD, USA and Knoxville, TN, USA?

American Airlines and Delta fly from Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS) every 3 hours. Alternatively, you can take a subway from Bethesda, Red Line Center Platform to Knoxville via Union Station, Red Line Center Platform, Washington Union Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 19h 6m.

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