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How to get fromBethesda to Louisvilleby plane, bus (Greyhound, Amtrak), train, bus, car, or subway

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There are 7 ways to get from Bethesda to Louisville by plane, bus (Greyhound, Amtrak), train, bus, car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Ronald Reagan Washington National Airport to Louisville International Airport

    best
    1. Fly from Ronald Reagan Washington National Airport (DCA) to Louisville International Airport (SDF)plane plane DCA - SDF
    4h 44m
    $165–1,009

  2. Fly Ronald Reagan Washington National Airport to Blue Grass Airport, drive

    cheapest
    1. Fly from Ronald Reagan Washington National Airport (DCA) to Blue Grass Airport (LEX)plane plane DCA - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 30m
    $102–575

  3. Bus

    1. Take the bus from Washington Union Station to Nashville Bus Stationbus bus Greyhound US0600
    2. Take the bus from Nashville to Louisville, KYbus bus Nashville
    21h 27m
    $142–232

  4. Train, bus (Amtrak)

    1. Take the train from Washington Union Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    22h 32m
    $414–697

  5. Drive  580.4 mi

    1. Drive from Bethesda to Louisvillecar car 580.4 mi
    9h 59m
    $106–153

  6. Subway to Washington Dulles International Airport, fly to Louisville International Airport

    1. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    2. Fly from Washington Dulles International Airport (IAD) to Louisville International Airport (SDF)plane plane IAD - SDF
    5h 9m
    $105–658

  7. Train to Baltimore-Washington International Airport, fly to Louisville International Airport

    1. Take the train from Washington Union Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF)plane plane BWI - SDF
    5h 12m
    $135–1,305

Bethesda to Louisville by bus

Calendar7Weekly Buses
Duration21h 27mAverage Duration
Ticket$142Cheapest Price
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Comparing Your Travel Options

Map of how to get from Bethesda to Louisville.ExpandLaunch map view
  • Distance: 491.5 mi
  • Duration: 4h 44m

What companies run services between Bethesda, MD, USA and Louisville, KY, USA?

American Airlines, Southwest Airlines, and Delta fly from Ronald Reagan Washington National Airport (DCA) to Louisville International Airport (SDF) every 3 hours. Alternatively, you can take a bus from Wisconsin Av NW+Albemarle St NW to Louisville, KY via Massachusetts Av NE+1 St NE, Washington Union Station, and Nashville in around 21h 27m.

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