There are 9 ways to get from Bethesda to Santee by plane, car, train, bus, taxi, subway, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Ronald Reagan Washington National Airport to Columbia, drive
best- Fly from Ronald Reagan Washington National Airport (DCA) to Columbia (CAE)plane DCA - CAE
- Drive from Columbia-Airport-CAE to Santeecar
4h 14m$245–1,422Drive 471.2 mi
cheapest- Drive from Bethesda to Santeecar 471.2 mi
8h$86–125Train, drive (Amtrak)
- Take the train from Washington Union Station to Charleston Amtrak Stationtrain Silver Meteor / ...
- Drive from Charleston Amtrak Station to Santeecar
11h 46m$172–358Bus, taxi
- Take the bus from Washington Union Station to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Sumter Bus Stopbus
- Take the taxi from Sumter Bus Stop to Santeetaxi
12h 9m$181–287Fly Ronald Reagan Washington National Airport to Charleston International Airport, drive
- Fly from Ronald Reagan Washington National Airport (DCA) to Charleston International Airport (CHS)plane DCA - CHS
- Drive from Charleston-Airport-CHS to Santeecar
4h 25m$445–1,122Subway to Washington Dulles International Airport, fly to Columbia, drive
- Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to Columbia (CAE)plane IAD - CAE
- Drive from Columbia-Airport-CAE to Santeecar
4h 41m$154–871Subway to Washington Dulles International Airport, fly to Charleston International Airport, drive
- Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to Charleston International Airport (CHS)plane IAD - CHS
- Drive from Charleston-Airport-CHS to Santeecar
5h$564–1,121Train to Baltimore-Washington International Airport, fly to Charleston International Airport, drive
- Take the train from Washington Union Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Charleston International Airport (CHS)plane BWI - CHS
- Drive from Charleston-Airport-CHS to Santeecar
4h 59m$404–1,768Bus
- Take the bus from Washington Union Station to Fayetteville Bus Stationbus FlixBus N2471 / ...
- Take the bus from Fayetteville Bus Station to Orangeburgbus Greyhound US0645S
13h 59m$162–257
Ronald Reagan Washington National Airport (DCA) to Columbia (CAE) flights
Questions & Answers
The cheapest way to get from Bethesda to Santee is to drive which costs $85 - $130 and takes 8h.
The fastest way to get from Bethesda to Santee is to fly and drive which takes 4h 14m and costs $240 - $1,500.
No, there is no direct bus from Bethesda station to Santee. However, there are services departing from Washington Union Station and arriving at Orangeburg via Fayetteville Bus Station. The journey, including transfers, takes approximately 13h 59m.
The distance between Bethesda and Santee is 482 miles. The road distance is 473.9 miles.
The best way to get from Bethesda to Santee without a car is to bus and taxi which takes 12h 9m and costs $180 - $290.
It takes approximately 4h 14m to get from Bethesda to Santee, including transfers.
Bethesda to Santee bus services, operated by Flixbus USA, depart from Washington Union Station.
Bethesda to Santee bus services, operated by Flixbus USA, arrive at Fayetteville Bus Station.
Yes, the driving distance between Bethesda to Santee is 474 miles. It takes approximately 8h to drive from Bethesda to Santee.
There are 41+ hotels available in Santee.
What companies run services between Bethesda, MD, USA and Santee, SC, USA?
You can take a subway from Bethesda, Red Line Center Platform to Santee via Union Station, Red Line Center Platform, Washington Union Station, Fayetteville Bus Station, and Orangeburg in around 13h 59m.
- Website
- aa.com
Flights from Ronald Reagan Washington National Airport to Columbia
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $230–1,400
Flights from Ronald Reagan Washington National Airport to Columbia via Charlotte
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- $240–1,400
Flights from Ronald Reagan Washington National Airport to Charleston International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $100–600
Flights from Ronald Reagan Washington National Airport to Charleston International Airport via Charlotte
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $100–650
Flights from Ronald Reagan Washington National Airport to Charleston International Airport via Philadelphia
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $130–700
Flights from Washington Dulles International Airport to Columbia via Charlotte
- Ave. Duration
- 3h 39m
- When
- Every day
- Estimated price
- $140–850
Flights from Washington Dulles International Airport to Charleston International Airport via Charlotte
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $60–360
Flights from Baltimore-Washington International Airport to Charleston International Airport via Charlotte
- Ave. Duration
- 3h 38m
- When
- Every day
- Estimated price
- $75–430
- Website
- delta.com
Flights from Ronald Reagan Washington National Airport to Columbia via Atlanta
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $330–1,700
Flights from Ronald Reagan Washington National Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $140–750
Flights from Washington Dulles International Airport to Columbia via Atlanta
- Ave. Duration
- 4h 1m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $190–1,000
Flights from Washington Dulles International Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $85–430
Flights from Baltimore-Washington International Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $100–550
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Charleston International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $70–420
- Website
- united.com
Flights from Washington Dulles International Airport to Columbia
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $140–850
Flights from Washington Dulles International Airport to Charleston International Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $60–350
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Washington Union Station to Charleston Amtrak Station
- Ave. Duration
- 9h 24m
- Frequency
- Twice daily
- Estimated price
- $160–340
- Website
- https://www.amtrak.com/home.html
Train from Washington Union Station to BWI Thurgood Marshall
- Ave. Duration
- 35 min
- Frequency
- Every 30 minutes
- Estimated price
- $9–20
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 202 466 3876
- Website
- wmata.com
Subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platform
- Ave. Duration
- 47 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- https://www.wmata.com
- standard fare after 9:30 p.m
- $2–3
Subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platform
- Ave. Duration
- 47 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- https://www.wmata.com
- standard fare after 9:30 p.m
- $2–3
- Phone
- 1-866-743-3682
- Website
- mta.maryland.gov
Train from Washington Union Station to BWI Thurgood Marshall
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- $2–9
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–9
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Washington Union Station to BWI Thurgood Marshall
- Ave. Duration
- 20 min
- Frequency
- Every 4 hours
- Estimated price
- $6–550
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $6–440
- First Class
- $100–550
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Washington Union Station to Raleigh Bus Station
- Ave. Duration
- 4h 40m
- Frequency
- Every 4 hours
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
Bus from Raleigh Bus Station to Sumter Bus Stop
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $29–55
- Website
- https://www.greyhound.com/
Bus from Fayetteville Bus Station to Orangeburg
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Washington Union Station to Raleigh Bus Station
- Ave. Duration
- 5h 5m
- Frequency
- Twice daily
- Estimated price
- $40–75
- Schedules at
- flixbus.com
Bus from Washington Union Station to Fayetteville Bus Station
- Ave. Duration
- 6h 20m
- Frequency
- Twice daily
- Estimated price
- $50–90
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide














