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How to get fromBig Pine Key to Jacksonvilleby plane, bus (Greyhound, Flixbus), bus, train, car, or shuttle

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There are 7 ways to get from Big Pine Key to Jacksonville by plane, bus (Greyhound, Flixbus), bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Key West International Airport to Jacksonville

    best
    1. Fly from Key West International Airport (EYW) to Jacksonville (JAX)plane plane EYW - JAX
    7h 22m
    $456–912

  2. Drive 473.7 mi

    cheapest
    1. Drive from Big Pine Key to Jacksonvillecar car 473.7 mi
    8h 25m
    $87–125

  3. Bus

    1. Take the bus from Big Pine Key to Miami Airport Stationbus bus Greyhound US0720s
    2. Take the bus from Miami Airport Station to Jacksonvillebus bus FlixBus 2431
    13h 15m
    $129–184

  4. Bus, train

    1. Take the bus from Big Pine Key to Miami Airport Stationbus bus Greyhound US0720s
    2. Take the train from Hollywood Amtrak Station to Jacksonvilletrain train Silver Meteor / ...
    14h 45m
    $173–323

  5. Shuttle to Miami International Airport, fly to Jacksonville

    1. Take a shuttle bus from Big Pine Key, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Jacksonville (JAX)plane plane MIA - JAX
    6h 57m
    $205–489

  6. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Jacksonville

    1. Take a shuttle bus from Big Pine Key, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Jacksonville (JAX)plane plane FLL - JAX
    7h 21m
    $292–948

  7. Fly Key West International Airport to Orlando Sanford, drive

    1. Fly from Key West International Airport (EYW) to Orlando Sanford (SFB)plane plane EYW - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Jacksonvillecar car
    5h 8m
    $157–414

Big Pine Key to Jacksonville by bus

Calendar22Weekly Buses
Duration13h 15mAverage Duration
Ticket$129Cheapest Price
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Questions & Answers

Map of how to get from Big Pine Key to Jacksonville.ExpandLaunch map view
  • Distance: 462.1 mi
  • Duration: 7h 22m

What companies run services between Big Pine Key, FL, USA and Jacksonville, FL, USA?

Delta and American Airlines fly from Key West International Airport (EYW) to Jacksonville (JAX) every 4 hours. Alternatively, you can take a bus from Big Pine Key to Jacksonville via Miami Airport Station in around 13h 15m.

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Train operators
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