There are 7 ways to get from Billerica to Syracuse by bus (Greyhound, Flixbus), train (Amtrak), car, train, plane, bus (Flixbus), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus Greyhound US0256S
- Take the bus from Boston to Syracuse Bus Stationbus Greyhound US0171 / ...
9h 35m$50–100Train (Amtrak)
- Take the train from Boston to Syracuse Regional Transportation Centertrain Lake Shore Limited
12h 4m$105–240Drive 293.8 mi
- Drive from Billerica to Syracusecar 293.8 mi
6h 20m$54–78Train, fly to Syracuse Hancock International Airport
- Take the train from North Billerica to Anderson/Woburntrain
- Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane BOS - SYR
5h 51m$92–577Bus via West Albany
- Take the bus from Boston to Albanybus FlixBus 2691
- Take the bus from Albany to Syracusebus Adt A264
10h 48m$52–95Fly to Rochester, train
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane BOS - ROC
- Take the train from Rochester to Syracuse Regional Transportation Centertrain
6h 49m$135–811Fly to Buffalo Niagara International Airport, bus
- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane BOS - BUF
- Take the bus from Buffalo Niagara International Airport to Syracuse Bus Stationbus
8h 4m$118–659
Billerica to Syracuse by bus
Questions & Answers
The cheapest way to get from Billerica to Syracuse is to bus which costs $50 - $100 and takes 9h 35m.
The fastest way to get from Billerica to Syracuse is to train and fly which takes 5h 51m and costs $90 - $600.
No, there is no direct bus from Billerica to Syracuse station. However, there are services departing from Boston Rd & Andover Rd and arriving at Syracuse Bus Station via Robert B Kennedy Bus Transfer Center and Boston. The journey, including transfers, takes approximately 9h 35m.
No, there is no direct train from Billerica to Syracuse. However, there are services departing from Alewife and arriving at Syracuse Regional Transportation Center via Boston. The journey, including transfers, takes approximately 12h 4m.
The distance between Billerica and Syracuse is 355 miles. The road distance is 295.6 miles.
The best way to get from Billerica to Syracuse without a car is to bus which takes 9h 35m and costs $50 - $100.
It takes approximately 9h 35m to get from Billerica to Syracuse, including transfers.
Billerica to Syracuse bus services, operated by Greyhound USA, depart from Robert B Kennedy Bus Transfer Center station.
Billerica to Syracuse train services, operated by Amtrak, depart from Boston station.
The best way to get from Billerica to Syracuse is to bus which takes 9h 35m and costs $50 - $100. Alternatively, you can train, which costs $100 - $240 and takes 12h 4m.
What companies run services between Billerica, MA, USA and Syracuse, NY, USA?
You can take a bus from Boston Rd & Andover Rd to Syracuse Bus Station via Robert B Kennedy Bus Transfer Center and Boston in around 9h 35m. Alternatively, Amtrak operates a train from Boston to Syracuse Regional Transportation Center once daily. Tickets cost $100–230 and the journey takes 9h 1m.
- Website
- aa.com
Flights from Boston Logan Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $80–550
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $85–600
Flights from Boston Logan Airport to Rochester via Philadelphia
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $110–650
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $80–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 3h 58m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–600
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 4h 3m
- When
- Saturday
- Estimated price
- $90–550
- Website
- southwest.com
Flights from Boston Logan Airport to Rochester via Baltimore
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $120–700
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 48m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $110–600
- Website
- jetblue.com
Flights from Boston Logan Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $80–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $80–550
- Website
- united.com
Flights from Boston Logan Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 53m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–700
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $90–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 3m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–650
- Website
- delta.com
Flights from Boston Logan Airport to Rochester via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday to Friday
- Estimated price
- $100–600
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Syracuse Regional Transportation Center
- Ave. Duration
- 9h 1m
- Frequency
- Once daily
- Estimated price
- $100–230
- Website
- Amtrak
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $24–55
- Website
- Amtrak
Train from North Billerica to Anderson/Woburn
- Ave. Duration
- 11 min
- Frequency
- Hourly
- Estimated price
- $1–8
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $1–8
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–150
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–90
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Robert B Kennedy Bus Transfer Center to Boston
- Ave. Duration
- 45 min
- Frequency
- 5 times a week
- Estimated price
- $4–8
- Website
- Greyhound
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 25m
- Frequency
- Twice daily
- Estimated price
- $45–90
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a week
- Estimated price
- $45–80
- Schedules at
- Flixbus USA
Bus from Boston to Albany
- Ave. Duration
- 3h 50m
- Frequency
- 3 times a week
- Estimated price
- $26–45
- Schedules at
- Flixbus USA
Bus from Albany to Syracuse
- Ave. Duration
- 2h 35m
- Frequency
- 3 times a week
- Estimated price
- $21–40
- Schedules at
- Flixbus USA
Bus from Buffalo Niagara International Airport to Syracuse Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Estimated price
- $22–40
- Schedules at
- Flixbus USA
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Albany to Syracuse
- Saver
- $26–85
- Flexible
- $50–90
Bus from Buffalo Niagara International Airport to Syracuse Bus Station
- Saver
- $27–85
- Flexible
- $50–90
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More Questions & Answers
Billerica to Syracuse bus services, operated by Greyhound USA, arrive at Boston station.
Billerica to Syracuse train services, operated by Amtrak, arrive at Syracuse Regional Transportation Center station.
Yes, the driving distance between Billerica to Syracuse is 296 miles. It takes approximately 6h 20m to drive from Billerica to Syracuse.
There are 94+ hotels available in Syracuse.

















