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How to get fromBiloxi to Great Smoky Mountainsby plane, car, bus, or train

Find Transport to Great Smoky Mountains

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There are 6 ways to get from Biloxi to Great Smoky Mountains by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport, drive

    best
    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Mcghee Tyson Airport (TYS)plane plane GPT - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    5h 57m
    $176–859

  2. Drive 567.9 mi

    cheapest
    1. Drive from Biloxi to Great Smoky Mountainscar car 567.9 mi
    10h 16m
    $104–150

  3. Bus, drive

    1. Take the bus from Biloxi to La Grange Bus Stationbus bus
    2. Take the bus from La Grange Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    20h 33m
    $166–275

  4. Bus, train, drive

    1. Take the bus from Biloxi Transit Center to New Orleans Bus Stationbus bus
    2. Take the train from New Orleans Union Passenger Terminal to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    30h 10m
    $323–696

  5. Fly to Asheville Regional Airport, drive

    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Asheville Regional Airport (AVL)plane plane GPT - AVL
    2. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    5h 59m
    $125–505

  6. Fly to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane GPT - ATL
    2. Drive from Atlanta-Airport-ATL to Great Smoky Mountainscar car
    5h 55m
    $156–648

Gulfport-Biloxi Regional Airport (GPT) to Mcghee Tyson Airport (TYS) flights

Calendar61Weekly Planes
Duration5h 14mAverage Duration
Ticket$138Cheapest Price
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Questions & Answers

Map of how to get from Biloxi to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 547.2 mi
  • Duration: 5h 57m

What companies run services between Biloxi, MS, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Biloxi to Great Smoky Mountains. However, you can take the taxi to Gulfport-Biloxi Regional Airport (GPT) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from Biloxi to Great Smoky Mountains via La Grange Bus Station, Atlanta Bus Station, Winston Salem(Trans Center), and Asheville, NC in around 20h 33m.

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