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How to get fromBiloxi to Knoxvilleby plane, bus, taxi, shuttle, car, or train

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There are 5 ways to get from Biloxi to Knoxville by plane, bus, taxi, shuttle, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport

    best
    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Mcghee Tyson Airport (TYS)plane plane GPT - TYS
    4h 22m
    $231–913

  2. Drive 563.9 mi

    cheapest
    1. Drive from Biloxi to Knoxvillecar car 563.9 mi
    9h 18m
    $103–149

  3. Bus, taxi, shuttle, drive

    1. Take the bus from Biloxi Transit Center to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte to Boonebus bus
    4. Take the taxi from Boone to Black Bear Resorttaxi taxi
    5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    6. Drive from Hot Springs to Chilhowee at Holstoncar car
    22h 21m

  4. Train, bus, taxi, shuttle, drive

    1. Take the train from Biloxi, MS to New Orleans, LA - Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to High Pointtrain train
    3. Take the bus from Forsyth Hospital to Boonebus bus
    4. Take the taxi from Boone to Black Bear Resorttaxi taxi
    5. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    6. Drive from Hot Springs to Knoxvillecar car
    33h 26m

  5. Fly to Asheville Regional Airport, drive

    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Asheville Regional Airport (AVL)plane plane GPT - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h 7m
    $133–508

Gulfport-Biloxi Regional Airport (GPT) to Mcghee Tyson Airport (TYS) flights

Calendar60Weekly Planes
Duration5h 14mAverage Duration
Ticket$140Cheapest Price
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Questions & Answers

Map of how to get from Biloxi to Knoxville.ExpandLaunch map view
  • Distance: 500.8 mi
  • Duration: 4h 22m

What companies run services between Biloxi, MS, USA and Knoxville, TN, USA?

Delta, United Airlines, and American Airlines fly from Gulfport-Biloxi Regional Airport (GPT) to Mcghee Tyson Airport (TYS) every 3 hours.

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