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How to get fromBiloxi to Louisvilleby plane, bus (Greyhound, Amtrak), car, bus, or bus (Greyhound)

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There are 6 ways to get from Biloxi to Louisville by plane, bus (Greyhound, Amtrak), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Gulfport-Biloxi Regional Airport to Louisville International Airport

    best
    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Louisville International Airport (SDF)plane plane GPT - SDF
    5h 14m
    $167–796

  2. Bus

    cheapest
    1. Take the bus from Biloxi Transit Center to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    15h 10m
    $112–177

  3. Drive  669.3 mi

    1. Drive from Biloxi to Louisvillecar car 669.3 mi
    11h 2m
    $123–177

  4. Fly Gulfport-Biloxi Regional Airport to Blue Grass Airport, drive

    1. Fly from Gulfport-Biloxi Regional Airport (GPT) to Blue Grass Airport (LEX)plane plane GPT - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 29m
    $124–482

  5. Bus to Mobile Regional Airport, fly to Louisville International Airport

    1. Take the bus from Biloxi Transit Center to Mobile Bus Stationbus bus
    2. Fly from Mobile Regional Airport (MOB) to Louisville International Airport (SDF)plane plane MOB - SDF
    7h 7m
    $143–696

  6. Bus via Preston @ Vim

    1. Take the bus from Biloxi Transit Center to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Nashville Bus Stationbus bus
    3. Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus bus
    16h 1m
    $120–192

Biloxi to Louisville by bus

Calendar14Weekly Buses
Duration15h 10mAverage Duration
Ticket$112Cheapest Price
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Comparing Your Travel Options

Map of how to get from Biloxi to Louisville.ExpandLaunch map view
  • Distance: 589.1 mi
  • Duration: 5h 14m

What companies run services between Biloxi, MS, USA and Louisville, KY, USA?

Delta, American Airlines, and United Airlines fly from Gulfport-Biloxi Regional Airport (GPT) to Louisville International Airport (SDF) every 3 hours. Alternatively, you can take a bus from Biloxi Transit Center to Louisville, KY via Montgomery Intermodal Center and Nashville in around 15h 10m.

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