There are 4 ways to get from Bocas Del Toro to Santiago by bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Changuinola to Santiagobus Changuinola
7h 40m$8–29Drive 358.7 km
- Drive from Changuinola to Santiagocar 358.7 km
5h 40m$50–71Fly, bus
- Fly from Bocas Del Toro Isla Colón International Airport (BOC) to Albrook Marcos A. Gelabert International Airport (PAC)plane BOC - PAC
- Take the bus from Gran Terminal Nacional de Transporte to Penonomébus
- Take the bus from Penonomé to Santiago de Veraguasbus
5h 32m$163–322Drive, bus
- Drive from Changuinola to Boquetecar
- Take the bus from Boquete to Davidbus
- Take the bus from David to Santiagobus
7h 4m$36–48
Bocas Del Toro to Santiago by bus
Questions & Answers
The cheapest way to get from Bocas Del Toro to Santiago is to bus which costs $8 - $29 and takes 7h 40m.
The fastest way to get from Bocas Del Toro to Santiago is to fly and bus which takes 5h 32m and costs $160 - $330.
Yes, there is a direct bus departing from Changuinola and arriving at Santiago. Services depart twice daily, and operate every day. The journey takes approximately 7h 40m.
The distance between Bocas Del Toro and Santiago is 387 km. The road distance is 358.7 km.
The best way to get from Bocas Del Toro to Santiago without a car is to bus which takes 7h 40m and costs $8 - $29.
The bus from Changuinola to Santiago takes 7h 40m including transfers and departs twice daily.
Bocas Del Toro to Santiago bus services, operated by Tranceibosa Bocas del Toro, depart from Changuinola station.
Bocas Del Toro to Santiago bus services, operated by Tranceibosa Bocas del Toro, arrive at Santiago station.
Yes, the driving distance between Bocas Del Toro to Santiago is 359 km. It takes approximately 5h 40m to drive from Bocas Del Toro to Santiago.
There are 20+ hotels available in Santiago.
What companies run services between Bocas Del Toro, Panama and Santiago, Panama?
Tranceibosa Bocas del Toro operates a bus from Changuinola to Santiago twice daily. Tickets cost $8–29 and the journey takes 7h 40m.
- Website
- airpanama.com
Flights from Bocas Del Toro Isla Colón International Airport to Albrook Marcos A. Gelabert International Airport
- Ave. Duration
- 1h
- When
- Monday to Thursday
- Estimated price
- $35–250
Flights from Bocas Del Toro Isla Colón International Airport to Albrook Marcos A. Gelabert International Airport
- Ave. Duration
- 1h 1m
- When
- Every day
- Estimated price
- $160–330
- Website
- 748airservicesltd.com
Flights from Bocas Del Toro Isla Colón International Airport to Albrook Marcos A. Gelabert International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $35–250
- Phone
- +507 303 6326
- [email protected]
- Website
- Tranceibosa Bocas del Toro
Bus from Changuinola to Santiago
- Ave. Duration
- 7h 40m
- Frequency
- Twice daily
- Estimated price
- $8–29
- Schedules at
- Tranceibosa Bocas del Toro
- Child
- $8–10
- Adult
- $16–20
- Phone
- +507 303-6466
Bus from Gran Terminal Nacional de Transporte to Penonomé
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- $6
Bus from Gran Terminal Nacional de Transporte to Penonomé
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $11–16
- Schedules at
- Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter)
- Road
- $11–16
Bus from Penonomé to Santiago de Veraguas
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $7–11
- Schedules at
- Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter)
- Road
- $7–11
- Phone
- +507 720 2311
- Website
- Coopsemautranchiri
Bus from Boquete to David
- Ave. Duration
- 45 min
- Frequency
- Every 20 minutes
- Estimated price
- $2
- Website
- Coopsemautranchiri
Bus from Boquete to David
- Ave. Duration
- 45 min
- Frequency
- Every 20 minutes
- Estimated price
- $2
Bus from David to Santiago
- Ave. Duration
- 3h 18m
- Frequency
- Hourly
Bus from David to Santiago
- Ave. Duration
- 2h 30m
- Frequency
- Every 2 hours
- Estimated price
- $11
- Schedules at
- Transporte Panama Chiriqui Frontera S.A (Panachif)
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