Rome2Rio

How to get fromBonita Springs to Santeeby bus, plane, car, bus (Flixbus), train, or taxi

Find Transport to Santee

See all options

There are 9 ways to get from Bonita Springs to Santee by bus, plane, car, bus (Flixbus), train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Fort Lauderdale–Hollywood International Airport, fly to Charleston International Airport, drive

    best
    1. Take the bus from Bonita Springs, FL to Fort Lauderdale International Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Charleston International Airport (CHS)plane plane FLL - CHS
    3. Drive from Charleston-Airport-CHS to Santeecar car
    5h 40m
    $198–1,146

  2. Drive 552.9 mi

    cheapest
    1. Drive from Bonita Springs to Santeecar car 552.9 mi
    9h 39m
    $101–146

  3. Bus (Flixbus)

    1. Take the bus from Bonita Springs, FL to Orlando Bus Stationbus bus FlixBus 2421
    2. Take the bus from Orlando Bus Station to Orangeburgbus bus FlixBus 2433
    15h 8m
    $179–274

  4. Bus, train, drive

    1. Take the bus from Bonita Springs, FL to Hollywood Sheridan Trirail Stationbus bus
    2. Take the train from Fort Lauderdale Amtrak Station to Charleston Amtrak Stationtrain train
    3. Drive from Charleston Amtrak Station to Santeecar car
    17h 15m
    $230–471

  5. Fly Ft. Myers to Charleston International Airport, drive

    1. Fly from Ft. Myers (RSW) to Charleston International Airport (CHS)plane plane RSW - CHS
    2. Drive from Charleston-Airport-CHS to Santeecar car
    6h 36m
    $114–524

  6. Bus to Miami International Airport, fly to Charleston International Airport, drive

    1. Take the bus from Bonita Springs, FL to Hollywood Sheridan Trirail Stationbus bus
    2. Fly from Miami International Airport (MIA) to Charleston International Airport (CHS)plane plane MIA - CHS
    3. Drive from Charleston-Airport-CHS to Santeecar car
    6h 59m
    $531–1,052

  7. Bus to Tampa, fly to Charleston International Airport, drive

    1. Take the bus from Bonita Springs, FL to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Charleston International Airport (CHS)plane plane TPA - CHS
    3. Drive from Charleston-Airport-CHS to Santeecar car
    9h 6m
    $178–402

  8. Fly Ft. Myers to Columbia, drive

    1. Fly from Ft. Myers (RSW) to Columbia (CAE)plane plane RSW - CAE
    2. Drive from Columbia-Airport-CAE to Santeecar car
    8h 40m
    $234–1,224

  9. Bus, taxi

    1. Take the bus from Bonita Springs, FL to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Walterboro, SCbus bus
    4. Take the taxi from Walterboro, SC to Santeetaxi taxi
    15h 20m
    $191–289

Fort Lauderdale–Hollywood International Airport (FLL) to Charleston International Airport (CHS) flights

Calendar26Weekly Planes
Duration2h 53mAverage Duration
Ticket$61Cheapest Price
See schedules

Questions & Answers

Map of how to get from Bonita Springs to Santee.ExpandLaunch map view
  • Distance: 644.4 mi
  • Duration: 5h 40m

What companies run services between Bonita Springs, FL, USA and Santee, SC, USA?

You can take a bus from Bonita Springs, FL to Santee via Orlando Bus Station and Orangeburg in around 15h 8m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound