Rome2Rio

How to get fromBoston Airport (BOS) to Mayo Clinicby plane, bus (Flixbus, Greyhound), train, bus, or car

Find Transport to Mayo Clinic

See all options

There are 7 ways to get from Boston Airport (BOS) to Mayo Clinic by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Boston Logan Airport (BOS) to Rochester (RST)plane plane BOS - RST
    6h 24m
    $108–522

  2. Bus

    1. Take the bus from Boston to New York Midtownbus bus
    2. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to Rochesterbus bus
    32h 30m
    $262–437

  3. Train, bus via Madison

    1. Take the train from Boston to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    33h 34m
    $404–839

  4. Drive 1,329.8 mi

    1. Drive from Boston Airport (BOS) to Mayo Cliniccar car 1,329.8 mi
    22h 34m
    $243–351

  5. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Boston Logan Airport (BOS) to Minneapolis–Saint Paul International Airport (MSP)plane plane BOS - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 2m
    $398–966

  6. Fly to Dane County Regional Airport-Truax Field, bus

    1. Fly from Boston Logan Airport (BOS) to Dane County Regional Airport-Truax Field (MSN)plane plane BOS - MSN
    2. Take the bus from Madison to Rochesterbus bus
    9h 14m
    $195–753

  7. Train, bus

    1. Take the train from Boston to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    34h 32m
    $487–1,019

Boston Airport (BOS) to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration32h 30mAverage Duration
Ticket$262Cheapest Price
See schedules

Questions & Answers

Map of how to get from Boston Airport (BOS) to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,094.2 mi
  • Duration: 6h 24m

What companies run services between Boston Airport (BOS), USA and Mayo Clinic, MN, USA?

Delta and American Airlines fly from Boston Logan Airport (BOS) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Logan International Airport to Mayo Clinic via Boston, South Station, Boston, New York Midtown, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 32h 30m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers