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How to get fromBoston to Florenceby plane, train, bus (Flixbus), train (Amtrak), car, bus, or bus (Greyhound)

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There are 9 ways to get from Boston to Florence by plane, train, bus (Flixbus), train (Amtrak), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Charleston International Airport, train

    best
    1. Fly from Boston Logan Airport (BOS) to Charleston International Airport (CHS)plane plane BOS - CHS
    2. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    7h 16m
    $655–1,005

  2. Bus

    cheapest
    1. Take the bus from Boston to NYC Downtownbus bus FlixBus 2611
    2. Take the bus from New York, NY to Florence, SCbus bus Nyc
    18h
    $116–180

  3. Train (Amtrak)

    1. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train Northeast Regional
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Florence Stationtrain train Palmetto / ...
    19h 43m
    $214–1,084

  4. Drive  832.8 mi

    1. Drive from Boston to Florencecar car 832.8 mi
    14h 54m
    $152–220

  5. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Boston Logan Airport (BOS) to Charlotte Douglas International Airport (CLT)plane plane BOS - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    7h 44m
    $169–419

  6. Fly to Wilmington International Airport, bus, train

    1. Fly from Boston Logan Airport (BOS) to Wilmington International Airport (ILM)plane plane BOS - ILM
    2. Take the bus from Wilmington Cape Fear Public Transit to Fayetteville Bus Stationbus bus
    3. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train
    8h 36m
    $141–573

  7. Fly to Myrtle Beach, bus, train

    1. Fly from Boston Logan Airport (BOS) to Myrtle Beach (MYR)plane plane BOS - MYR
    2. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    3. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    8h 22m
    $122–466

  8. Fly to Raleigh-Durham International Airport, train

    1. Fly from Boston Logan Airport (BOS) to Raleigh-Durham International Airport (RDU)plane plane BOS - RDU
    2. Take the train from Raleigh Union Station to Selma Stationtrain train
    3. Take the train from Selma Station to Florence Stationtrain train
    8h 50m
    $183–968

  9. Bus via Raleigh (Greyhound)

    1. Take the bus from Boston to Port Authority Bus Terminalbus bus
    2. Take the bus from Port Authority Bus Terminal to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    19h 25m
    $136–266

Boston to Florence by train (Amtrak)

Calendar14Weekly Trains
Duration19h 43mAverage Duration
Ticket$214Cheapest Price
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Questions & Answers

Map of how to get from Boston to Florence.ExpandLaunch map view
  • Distance: 929.4 mi
  • Duration: 7h 16m

What companies run services between Boston, MA, USA and Florence, SC, USA?

You can take a bus from Boston to Florence, SC via NYC Downtown and New York, NY in around 18h. Alternatively, you can take a train from Boston to Florence Station via Ny Moynihan Train Hall At Penn Station in around 19h 43m.

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Bus operators

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