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How to get fromBoston to Jefferson Cityby plane, train (Amtrak), bus, train, car, shuttle, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Boston to Jefferson City by plane, train (Amtrak), bus, train, car, shuttle, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Boston Logan Airport to Columbia Regional Airport

    best
    1. Fly from Boston Logan Airport (BOS) to Columbia Regional Airport (COU)plane plane BOS - COU
    5h 52m
    $200–594

  2. Train (Amtrak)

    1. Take the train from Boston to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to Jefferson City Stationtrain train Lincoln Service Missouri River Runner
    31h 8m
    $464–938

  3. Bus, train

    1. Take the bus from Boston to New York Midtownbus bus
    2. Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Jefferson City Stationtrain train
    31h 56m
    $233–445

  4. Drive 1,272.1 mi

    1. Drive from Boston to Jefferson Citycar car 1,272.1 mi
    22h 39m
    $233–336

  5. Fly Boston Logan Airport to Lambert–St. Louis International Airport, shuttle

    1. Fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL)plane plane BOS - STL
    2. Take a shuttle bus from St Louis International Airport to Jefferson City, Missourishuttle bus
    5h 50m
    $499–993

  6. Bus to Manchester Airport, fly to Columbia Regional Airport

    1. Take the bus from Boston to Boston Manchester Airportbus bus
    2. Fly from Manchester Airport (MHT) to Columbia Regional Airport (COU)plane plane MHT - COU
    8h 26m
    $218–675

  7. Train to Theodore Francis Green State Airport, fly to Columbia Regional Airport

    1. Take the train from South Station to TF Green Airporttrain train
    2. Fly from Theodore Francis Green State Airport (PVD) to Columbia Regional Airport (COU)plane plane PVD - COU
    9h 18m
    $200–586

  8. Bus

    1. Take the bus from Boston to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Jefferson Citybus bus
    33h 58m
    $226–443

Boston to Jefferson City by train (Amtrak)

Calendar7Weekly Trains
Duration31h 8mAverage Duration
Ticket$464Cheapest Price
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Questions & Answers

Map of how to get from Boston to Jefferson City.ExpandLaunch map view
  • Distance: 1,158.5 mi
  • Duration: 5h 52m

What companies run services between Boston, MA, USA and Jefferson City, MO, USA?

American Airlines and United Airlines fly from Boston Logan Airport (BOS) to Columbia Regional Airport (COU) every 3 hours. Alternatively, you can take a train from Boston to Jefferson City Station via Chicago Union Station in around 31h 8m.

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Bus operators

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