There are 8 ways to get from Boston to Jefferson City by ferry, plane, train (Amtrak), bus, train, car, shuttle, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry to Boston Logan Airport, fly to Columbia Regional Airport
best- Take the ferry from Long Wharf to Logan Airport Ferry Terminalferry
- Fly from Boston Logan Airport (BOS) to Columbia Regional Airport (COU)plane BOS - COU
7h 24m$204–670Bus to Manchester Airport, fly to Columbia Regional Airport
cheapest- Take the bus from Boston to Boston Manchester Airportbus
- Fly from Manchester Airport (MHT) to Columbia Regional Airport (COU)plane MHT - COU
7h 50m$199–603Train (Amtrak)
- Take the train from Boston to Chicago Union Stationtrain Lake Shore Limited
- Take the train from Chicago Union Station to Jefferson City Stationtrain Lincoln Service Missouri River Runner
31h 8m$781–1,211Bus, train
- Take the bus from Boston to New Yorkbus
- Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus
- Take the train from St. Louis to Jefferson City Stationtrain
32h$288–464Drive 1,272.1 mi
- Drive from Boston to Jefferson Citycar 1,272.1 mi
22h 38m$233–336Train to Theodore Francis Green State Airport, fly to Columbia Regional Airport
- Take the train from South Station to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Columbia Regional Airport (COU)plane PVD - COU
8h 40m$220–726Ferry to Boston Logan Airport, fly to Lambert–St. Louis International Airport, shuttle
- Take the ferry from Long Wharf to Logan Airport Ferry Terminalferry
- Fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL)plane BOS - STL
- Take a shuttle bus from St Louis International Airport to Jefferson City, Missouri
7h 35m$599–1,060Bus
- Take the bus from Boston to Newark Penn Stationbus
- Take the bus from Newark Penn Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Jefferson Citybus
33h 58m$248–383
Boston to Jefferson City by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Boston to Jefferson City is to drive which costs $230 - $340 and takes 22h 38m.
The fastest way to get from Boston to Jefferson City is to ferry and fly which takes 7h 24m and costs $200 - $700.
No, there is no direct bus from Boston to Jefferson City. However, there are services departing from Boston and arriving at Jefferson City via Newark Penn Station and St Louis Bus Station. The journey, including transfers, takes approximately 33h 58m.
No, there is no direct train from Boston to Jefferson City station. However, there are services departing from Boston and arriving at Jefferson City Station via Chicago Union Station. The journey, including transfers, takes approximately 31h 8m.
The distance between Boston and Jefferson City is 1168 miles. The road distance is 1279.5 miles.
The best way to get from Boston to Jefferson City without a car is to train which takes 31h 8m and costs $750 - $1,300.
It takes approximately 7h 24m to get from Boston to Jefferson City, including transfers.
Boston to Jefferson City bus services, operated by Greyhound USA, depart from Boston station.
Boston to Jefferson City train services, operated by Amtrak, depart from Boston station.
The best way to get from Boston to Jefferson City is to train which takes 31h 8m and costs $750 - $1,300. Alternatively, you can bus, which costs $240 - $390 and takes 33h 58m.
What companies run services between Boston, MA, USA and Jefferson City, MO, USA?
You can take a train from Boston to Jefferson City Station via Chicago Union Station in around 31h 8m. Alternatively, you can take a bus from Boston to Jefferson City via Newark Penn Station, St Louis Bus Station, and Jefferson City in around 33h 58m.
- Website
- aa.com
Flights from Boston Logan Airport to Columbia Regional Airport via Charlotte
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $130–600
Flights from Boston Logan Airport to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 39m
- When
- Every day
- Estimated price
- $110–550
Flights from Boston Logan Airport to Columbia Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 16m
- When
- Every day
- Estimated price
- $170–750
Flights from Manchester Airport to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $100–480
Flights from Manchester Airport to Columbia Regional Airport via Charlotte
- Ave. Duration
- 8h 36m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–550
Flights from Manchester Airport to Columbia Regional Airport via Philadelphia, Chicago O'Hare
- Ave. Duration
- 11h 23m
- When
- Every day
- Estimated price
- $100–500
Flights from Theodore Francis Green State Airport to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 32m
- When
- Every day
- Estimated price
- $120–600
Flights from Theodore Francis Green State Airport to Columbia Regional Airport via Charlotte
- Ave. Duration
- 6h 36m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–650
Flights from Boston Logan Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 3h 14m
- When
- Every day
- Estimated price
- $130–700
- Website
- southwest.com
Flights from Boston Logan Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 3h 1m
- When
- Every day
- Estimated price
- $130–700
Flights from Boston Logan Airport to Lambert–St. Louis International Airport via Baltimore
- Ave. Duration
- 4h 53m
- When
- Tuesday to Wednesday
- Estimated price
- $140–700
Flights from Boston Logan Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 5h 7m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $140–700
- Website
- united.com
Flights from Boston Logan Airport to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $110–550
Flights from Boston Logan Airport to Columbia Regional Airport via Denver
- Ave. Duration
- 9h 59m
- When
- Every day
- Estimated price
- $190–800
Flights from Theodore Francis Green State Airport to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $120–600
Flights from Theodore Francis Green State Airport to Columbia Regional Airport via Denver
- Ave. Duration
- 7h 23m
- When
- Saturday
- Estimated price
- $210–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Chicago Union Station
- Ave. Duration
- 22h 22m
- Frequency
- Once daily
- Estimated price
- $550–900
- Website
- Amtrak
Train from Chicago Union Station to Jefferson City Station
- Ave. Duration
- 7h 46m
- Frequency
- Once daily
- Estimated price
- $220–350
- Website
- Amtrak
Train from St. Louis to Jefferson City Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $65–110
- Website
- Amtrak
Train from South Station to TF Green Airport
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from Boston to New York
- Ave. Duration
- 4h 35m
- Frequency
- Hourly
- Estimated price
- $40–75
- Website
- Peter Pan
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Port Authority Bus Terminal to St Louis Bus Station
- Ave. Duration
- 23h
- Frequency
- 3 times a day
- Estimated price
- $180–280
- Website
- Greyhound
Bus from Boston to Boston Manchester Airport
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $9–14
- Website
- Greyhound
Bus from Boston to Newark Penn Station
- Ave. Duration
- 5h 20m
- Frequency
- 4 times a day
- Estimated price
- $45–70
- Website
- Greyhound
Bus from Newark Penn Station to St Louis Bus Station
- Ave. Duration
- 22h 30m
- Frequency
- Once daily
- Estimated price
- $170–260
- Website
- Greyhound
Bus from St Louis Bus Station to Jefferson City
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- Greyhound
- Phone
- 573-368-4656
- [email protected]
- Website
- USA Express
Shuttle from St Louis International Airport to Jefferson City, Missouri
- Ave. Duration
- 2h
- Frequency
- 4 times a day
- Estimated price
- $135–150
- Website
- USA Express
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to Newark Penn Station
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a day
- Estimated price
- $40–60
- Schedules at
- Flixbus USA
Ferry from Long Wharf to Logan Airport Ferry Terminal
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- $3–10
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–10
Ferry from Long Wharf to Logan Airport Ferry Terminal
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- $3–10
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–10
Want to know more about travelling around United States
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Booking & Getting There
Boston to Jefferson City bus services, operated by Greyhound USA, arrive at Newark Penn Station.
Jefferson City is 1h behind Boston. It is currently 5:51 AM in Boston and 4:51 AM in Jefferson City.
Boston to Jefferson City train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Boston to Jefferson City is 1280 miles. It takes approximately 22h 38m to drive from Boston to Jefferson City.
Book your Boston to Jefferson City train tickets online with Omio.
Book your Boston to Jefferson City bus tickets online with Omio.
There are 21+ hotels available in Jefferson City.













