There are 9 ways to get from Boston to Knoxville by ferry, plane, train, bus, car, bus (Flixbus), or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry to Boston Logan Airport, fly to Mcghee Tyson Airport
best- Take the ferry from Long Wharf to Logan Airport Ferry Terminalferry
- Fly from Boston Logan Airport (BOS) to Mcghee Tyson Airport (TYS)plane BOS - TYS
4h 28m$279–1,280Ferry to Boston Logan Airport, fly to Asheville Regional Airport, drive
cheapest- Take the ferry from Long Wharf to Logan Airport Ferry Terminalferry
- Fly from Boston Logan Airport (BOS) to Asheville Regional Airport (AVL)plane BOS - AVL
- Drive from Asheville-Airport-AVL to Knoxvillecar
6h 16m$111–515Train, bus via Farragut
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain Northeast Regional
- Take the bus from New York to Knoxvillebus Nyc
17h 35m$237–967Drive 909.8 mi
- Drive from Boston to Knoxvillecar 909.8 mi
15h 57m$166–240Bus to Manchester Airport, fly to Mcghee Tyson Airport
- Take the bus from Boston to Boston Manchester Airportbus
- Fly from Manchester Airport (MHT) to Mcghee Tyson Airport (TYS)plane MHT - TYS
6h 32m$264–1,183Train to Theodore Francis Green State Airport, fly to Mcghee Tyson Airport
- Take the train from South Station to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Mcghee Tyson Airport (TYS)plane PVD - TYS
7h 3m$295–1,386Train, bus
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain Northeast Regional
- Take the bus from New York, NY to Knoxville, TNbus Ny
17h 39m$192–877Bus
- Take the bus from Boston to NYC Downtownbus FlixBus 2611
- Take the bus from New York to Knoxvillebus Nyc
18h 6m$214–300Bus via New York
- Take the bus from Boston to Port Authority Bus Terminalbus Greyhound US0230 / ...
- Take the bus from New York to Knoxvillebus Nyc
18h 27m$222–310
Boston Logan Airport (BOS) to Mcghee Tyson Airport (TYS) flights
Comparing Your Travel Options
The cheapest way to get from Boston to Knoxville is to drive which costs $160 - $240 and takes 15h 57m.
The fastest way to get from Boston to Knoxville is to ferry and fly which takes 4h 28m and costs $270 - $1,300.
No, there is no direct bus from Boston to Knoxville. However, there are services departing from Boston and arriving at Knoxville via New York. The journey, including transfers, takes approximately 18h 6m.
The distance between Boston and Knoxville is 849 miles. The road distance is 915.1 miles.
The best way to get from Boston to Knoxville without a car is to train and bus via Farragut which takes 17h 35m and costs $230 - $1,000.
It takes approximately 4h 28m to get from Boston to Knoxville, including transfers.
Boston to Knoxville bus services, operated by Flixbus USA, depart from Boston station.
Boston to Knoxville bus services, operated by Flixbus USA, arrive at NYC Downtown station.
Yes, the driving distance between Boston to Knoxville is 915 miles. It takes approximately 15h 57m to drive from Boston to Knoxville.
There are 319+ hotels available in Knoxville.
What companies run services between Boston, MA, USA and Knoxville, TN, USA?
You can take a bus from Boston to Knoxville via NYC Downtown, New York, and Knoxville in around 18h 6m.
- Website
- aa.com
Flights from Boston Logan Airport to Mcghee Tyson Airport via Reagan Washington
- Ave. Duration
- 4h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $220–1,200
Flights from Boston Logan Airport to Mcghee Tyson Airport via Philadelphia
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Manchester Airport to Mcghee Tyson Airport via Reagan Washington
- Ave. Duration
- 6h 7m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–1,100
Flights from Manchester Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Manchester Airport to Mcghee Tyson Airport via Philadelphia
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $200–1,100
Flights from Manchester Airport to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 5h 46m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $270–1,300
Flights from Theodore Francis Green State Airport to Mcghee Tyson Airport via Reagan Washington
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $230–1,300
Flights from Theodore Francis Green State Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $240–1,300
Flights from Theodore Francis Green State Airport to Mcghee Tyson Airport via Philadelphia
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $230–1,300
Flights from Boston Logan Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h 30m
- When
- Saturday, Thursday, Sunday, Friday, Monday, and Wednesday
- Estimated price
- $90–480
Flights from Boston Logan Airport to Asheville Regional Airport via Philadelphia
- Ave. Duration
- 4h 46m
- When
- Saturday to Wednesday
- Estimated price
- $85–470
- Website
- delta.com
Flights from Boston Logan Airport to Mcghee Tyson Airport via New York La Guardia
- Ave. Duration
- 4h 59m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $220–1,200
Flights from Theodore Francis Green State Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $270–1,400
Flights from Theodore Francis Green State Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $270–1,400
Flights from Boston Logan Airport to Asheville Regional Airport
- Ave. Duration
- 2h 41m
- When
- Saturday and Sunday
- Estimated price
- $85–470
Flights from Boston Logan Airport to Asheville Regional Airport via New York La Guardia
- Ave. Duration
- 4h 33m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–470
Flights from Boston Logan Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $110–550
- Website
- southwest.com
Flights from Boston Logan Airport to Mcghee Tyson Airport via Baltimore
- Ave. Duration
- 5h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $220–1,200
Flights from Boston Logan Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 5h 20m
- When
- Tuesday and Wednesday
- Estimated price
- $270–1,400
Flights from Manchester Airport to Mcghee Tyson Airport via Baltimore
- Ave. Duration
- 4h 40m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $200–1,100
Flights from Manchester Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 6h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,200
Flights from Theodore Francis Green State Airport to Mcghee Tyson Airport via Baltimore
- Ave. Duration
- 4h 40m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $230–1,300
Flights from Theodore Francis Green State Airport to Mcghee Tyson Airport via Nashville
- Ave. Duration
- 9h 10m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $270–1,400
- Website
- united.com
Flights from Boston Logan Airport to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Manchester Airport to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $200–1,100
Flights from Theodore Francis Green State Airport to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $230–1,300
- Website
- allegiantair.com
Flights from Boston Logan Airport to Mcghee Tyson Airport
- Ave. Duration
- 2h 30m
- When
- Saturday, Thursday, Sunday, and Tuesday
- Estimated price
- $220–1,200
Flights from Boston Logan Airport to Asheville Regional Airport
- Ave. Duration
- 2h 23m
- When
- Friday and Monday
- Estimated price
- $85–470
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 49m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 49m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from South Station to TF Green Airport
- Ave. Duration
- 1h 24m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $95–140
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $95–140
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $95–140
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston to Boston Manchester Airport
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $9–14
- Website
- Greyhound
Bus from Boston to Port Authority Bus Terminal
- Ave. Duration
- 4h 50m
- Frequency
- Hourly
- Estimated price
- $35–60
- Website
- Greyhound
- Phone
- +1 615-939-8887
- [email protected]
- Website
- New York to Tennessee Bus
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- New York to Tennessee Bus
- Adult One-way
- $95–110
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to NYC Downtown
- Ave. Duration
- 5h
- Frequency
- Every 4 hours
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Ferry from Long Wharf to Logan Airport Ferry Terminal
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- $3–10
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–10
Ferry from Long Wharf to Logan Airport Ferry Terminal
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- $3–10
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–10
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