There are 10 ways to get from Boston to La Crosse by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Boston Logan Airport to La Crosse
best- Fly from Boston Logan Airport (BOS) to La Crosse (LSE)plane BOS - LSE
5h 26m$123–501Train (Amtrak)
- Take the train from Boston to Chicago Union Stationtrain Lake Shore Limited
- Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain Empire Builder / ...
28h 21m$361–800Bus
- Take the bus from Boston to Newark Penn Stationbus
- Take the bus from Newark Penn Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus
- Take the bus from Milwaukee to La Crossebus
30h$208–358Drive 1,261.5 mi
- Drive from Boston to La Crossecar 1,261.5 mi
21h 28m$231–333Fly Boston Logan Airport to Dane County Regional Airport-Truax Field, bus
- Fly from Boston Logan Airport (BOS) to Dane County Regional Airport-Truax Field (MSN)plane BOS - MSN
- Take the bus from Madison to La Crossebus
7h 7m$181–745Bus to Manchester Airport, fly to La Crosse
- Take the bus from Boston to Boston Manchester Airportbus
- Fly from Manchester Airport (MHT) to La Crosse (LSE)plane MHT - LSE
7h 41m$146–637Fly Boston Logan Airport to Minneapolis–Saint Paul International Airport, train
- Fly from Boston Logan Airport (BOS) to Minneapolis–Saint Paul International Airport (MSP)plane BOS - MSP
- Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain
7h 37m$418–1,086Train to Theodore Francis Green State Airport, fly to La Crosse
- Take the train from South Station to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to La Crosse (LSE)plane PVD - LSE
8h 12m$124–499Fly Boston Logan Airport to General Mitchell International Airport, train
- Fly from Boston Logan Airport (BOS) to General Mitchell International Airport (MKE)plane BOS - MKE
- Take the train from Milwaukee to La Crosse Amtrak Stationtrain
7h 32m$716–1,961Train, bus
- Take the train from Boston to Chicago Union Stationtrain
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to La Crossebus
29h 59m$346–730
Boston to La Crosse by train (Amtrak)
Questions & Answers
The cheapest way to get from Boston to La Crosse is to bus which costs $200 - $360 and takes 30h.
The fastest way to get from Boston to La Crosse is to fly which takes 5h 26m and costs $120 - $500.
No, there is no direct bus from Boston to La Crosse. However, there are services departing from Boston and arriving at La Crosse via Newark Penn Station, Chicago Bus Station and Milwaukee. The journey, including transfers, takes approximately 30h.
No, there is no direct train from Boston to La Crosse station. However, there are services departing from Boston and arriving at La Crosse Amtrak Station via Chicago Union Station. The journey, including transfers, takes approximately 28h 21m.
The distance between Boston and La Crosse is 1037 miles. The road distance is 1268.9 miles.
The best way to get from Boston to La Crosse without a car is to train which takes 28h 21m and costs $360 - $800.
It takes approximately 5h 26m to get from Boston to La Crosse, including transfers.
Boston to La Crosse bus services, operated by Greyhound USA, depart from Boston station.
Boston to La Crosse train services, operated by Amtrak, depart from Boston station.
The best way to get from Boston to La Crosse is to fly which takes 5h 26m and costs $120 - $500. Alternatively, you can train, which costs $360 - $800 and takes 28h 21m, you could also bus, which costs $200 - $360 and takes 30h.
What companies run services between Boston, MA, USA and La Crosse, WI, USA?
American Airlines flies from Boston Logan Airport (BOS) to La Crosse (LSE) every 4 hours. Alternatively, you can take a train from Boston to La Crosse Amtrak Station via Chicago Union Station in around 28h 21m.
- Website
- delta.com
Flights from Boston Logan Airport to Dane County Regional Airport-Truax Field
- Ave. Duration
- 2h 48m
- When
- Every day
- Estimated price
- $140–700
Flights from Boston Logan Airport to Dane County Regional Airport-Truax Field via Detroit
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $140–700
Flights from Boston Logan Airport to Dane County Regional Airport-Truax Field via New York La Guardia
- Ave. Duration
- 5h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–750
Flights from Boston Logan Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- $130–600
Flights from Boston Logan Airport to Minneapolis–Saint Paul International Airport via General Mitchell International Airport
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $130–650
Flights from Boston Logan Airport to Minneapolis–Saint Paul International Airport via Dane County Regional Airport-Truax Field
- Ave. Duration
- 6h 57m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
Flights from Boston Logan Airport to General Mitchell International Airport
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- $120–650
Flights from Boston Logan Airport to General Mitchell International Airport via Detroit
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $120–650
Flights from Boston Logan Airport to General Mitchell International Airport via New York La Guardia
- Ave. Duration
- 4h 52m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
- Website
- aa.com
Flights from Boston Logan Airport to La Crosse via Chicago O'Hare
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $100–480
Flights from Boston Logan Airport to La Crosse via Syracuse, Chicago O'Hare
- Ave. Duration
- 8h 47m
- When
- Every day
- Estimated price
- $100–480
Flights from Boston Logan Airport to La Crosse via Rochester, Chicago O'Hare
- Ave. Duration
- 9h 40m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–480
Flights from Boston Logan Airport to La Crosse via Buffalo, Chicago O'Hare
- Ave. Duration
- 10h 16m
- When
- Every day
- Estimated price
- $100–480
Flights from Boston Logan Airport to Dane County Regional Airport-Truax Field
- Ave. Duration
- 2h 46m
- When
- Every day
- Estimated price
- $140–700
Flights from Boston Logan Airport to Dane County Regional Airport-Truax Field via Philadelphia
- Ave. Duration
- 5h 20m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $150–750
Flights from Boston Logan Airport to Dane County Regional Airport-Truax Field via Reagan Washington
- Ave. Duration
- 5h 23m
- When
- Monday to Saturday
- Estimated price
- $160–750
Flights from Boston Logan Airport to Dane County Regional Airport-Truax Field via Chicago O'Hare
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $140–700
Flights from Manchester Airport to La Crosse via Chicago O'Hare
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $120–600
Flights from Manchester Airport to La Crosse via Reagan Washington, Chicago O'Hare
- Ave. Duration
- 8h 16m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–650
Flights from Manchester Airport to La Crosse via Philadelphia, Chicago O'Hare
- Ave. Duration
- 10h 12m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $140–650
Flights from Theodore Francis Green State Airport to La Crosse via Chicago O'Hare
- Ave. Duration
- 6h 31m
- When
- Every day
- Estimated price
- $95–460
Flights from Theodore Francis Green State Airport to La Crosse via Philadelphia, Chicago O'Hare
- Ave. Duration
- 8h 56m
- When
- Every day
- Estimated price
- $100–480
- Website
- united.com
Flights from Boston Logan Airport to Dane County Regional Airport-Truax Field via Chicago O'Hare
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $140–700
Flights from Boston Logan Airport to Dane County Regional Airport-Truax Field via Newark
- Ave. Duration
- 5h 13m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–750
Flights from Boston Logan Airport to General Mitchell International Airport via Chicago O'Hare
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $130–650
- Website
- southwest.com
Flights from Boston Logan Airport to General Mitchell International Airport via Chicago Midway
- Ave. Duration
- 4h 45m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $130–650
Flights from Boston Logan Airport to General Mitchell International Airport via Baltimore
- Ave. Duration
- 4h 50m
- When
- Tuesday and Wednesday
- Estimated price
- $140–700
- Website
- suncountry.com
Flights from Boston Logan Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 9m
- When
- Every day
- Estimated price
- $130–600
- Website
- jetblue.com
Flights from Boston Logan Airport to General Mitchell International Airport
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- $120–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Chicago Union Station
- Ave. Duration
- 22h 22m
- Frequency
- Once daily
- Estimated price
- $280–650
- Website
- Amtrak
Train from Chicago Union Station to La Crosse Amtrak Station
- Ave. Duration
- 4h 59m
- Frequency
- 3 times a day
- Estimated price
- $75–180
- Website
- Amtrak
Train from St. Paul-Minneapolis to La Crosse Amtrak Station
- Ave. Duration
- 2h 47m
- Frequency
- 3 times a day
- Estimated price
- $35–80
- Website
- Amtrak
Train from Milwaukee to La Crosse Amtrak Station
- Ave. Duration
- 3h 19m
- Frequency
- 3 times a day
- Estimated price
- $55–120
- Website
- Amtrak
Train from Boston to Chicago Union Station
- Ave. Duration
- 22h 22m
- Frequency
- Once daily
- Estimated price
- $280–650
- Website
- Amtrak
Train from South Station to TF Green Airport
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston to Newark Penn Station
- Ave. Duration
- 5h 20m
- Frequency
- 5 times a day
- Estimated price
- $35–70
- Website
- Greyhound
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $12–24
- Website
- Greyhound
Bus from Boston to Boston Manchester Airport
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $7–14
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to Newark Penn Station
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a day
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Bus from Newark Penn Station to Chicago Bus Station
- Ave. Duration
- 16h 20m
- Frequency
- Twice daily
- Estimated price
- $110–190
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $12–21
- Schedules at
- Flixbus USA
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to La Crosse
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Madison to La Crosse
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
Bus from Madison to La Crosse
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- Rockland Coaches
- Adult
- $25–55
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More Questions & Answers
Boston to La Crosse bus services, operated by Greyhound USA, arrive at Newark Penn Station.
La Crosse is 1h behind Boston. It is currently 5:27 PM in Boston and 4:27 PM in La Crosse.
Boston to La Crosse train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Boston to La Crosse is 1269 miles. It takes approximately 21h 28m to drive from Boston to La Crosse.
Book your Boston to La Crosse train tickets online with Omio.
Book your Boston to La Crosse bus tickets online with Omio.
There are 48+ hotels available in La Crosse.














