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How to get fromBoston to Saint Charlesby ferry, plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or bus (Flixbus, Greyhound)

Find Transport to Saint Charles

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There are 6 ways to get from Boston to Saint Charles by ferry, plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Ferry to Boston Logan Airport, fly

    best
    1. Take the ferry from Long Wharf to Logan Airport Ferry Terminalferry ferry
    2. Fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL)plane plane BOS - STL
    5h 57m
    $484–934

  2. Bus to Barnstable Municipal Airport, fly

    cheapest
    1. Take the bus from Boston to Barnstable Airportbus bus
    2. Fly from Barnstable Municipal Airport (HYA) to Lambert–St. Louis International Airport (STL)plane plane HYA - STL
    9h
    $184–848

  3. Train (Amtrak)

    1. Take the train from Boston to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    29h 42m
    $729–1,122

  4. Bus

    1. Take the bus from Boston to Newark Penn Stationbus bus Greyhound US0235 / ...
    2. Take the bus from Newark Penn Station to St Louis Bus Stationbus bus Greyhound US0421
    30h 12m
    $229–361

  5. Drive  1,164.6 mi

    1. Drive from Boston to Saint Charlescar car 1,164.6 mi
    20h 41m
    $213–307

  6. Bus via Alewife

    1. Take the bus from Cambridge to Newark Penn Stationbus bus FlixBus 2619
    2. Take the bus from Newark Penn Station to St Louis Bus Stationbus bus Greyhound US0421
    32h 7m
    $237–366

Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL) flights

Calendar65Weekly Planes
Duration3h 31mAverage Duration
Ticket$144Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Boston to Saint Charles.ExpandLaunch map view
  • Distance: 1,066 mi
  • Duration: 5h 57m

What companies run services between Boston, MA, USA and Saint Charles, MO, USA?

You can take a train from Boston to Saint Charles via Chicago Union Station, St. Louis, CIVIC CENTER station, NORTH HANLEY station, North Hanley Transit Center, and 4375 Rider Trail North Sb in around 29h 42m. Alternatively, you can take a bus from Boston to Saint Charles via Newark Penn Station, St Louis Bus Station, Civic Center Transit Center, North Hanley Transit Center, and 4375 Rider Trail North Sb in around 30h 12m.

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