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How to get fromBoston to Santa Fe Depotby ferry, plane, train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car, bus, or train

Find Transport to Santa Fe Depot

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There are 6 ways to get from Boston to Santa Fe Depot by ferry, plane, train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Ferry to Boston Logan Airport, fly

    best
    1. Take the ferry from Long Wharf to Logan Airport Ferry Terminalferry ferry
    2. Fly from Boston Logan Airport (BOS) to San Diego International Airport (SAN)plane plane BOS - SAN
    8h 31m
    $166–425

  2. Train (Amtrak)

    1. Take the train from Boston to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    3. Take the train from Fullerton Amtrak Station to San Diegotrain train
    2d 21h
    $1,814–2,848

  3. Bus

    1. Take the bus from Boston to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles to San Diegobus bus
    3d 1h

  4. Drive  2,948.4 mi

    1. Drive from Boston to Santa Fe Depotcar car 2,948.4 mi
    2d 1h
    $539–778

  5. Bus to Barnstable Municipal Airport, fly

    1. Take the bus from Boston to Barnstable Airportbus bus
    2. Fly from Barnstable Municipal Airport (HYA) to San Diego International Airport (SAN)plane plane HYA - SAN
    11h 51m
    $226–879

  6. Bus, train

    1. Take the bus from Boston to New York Midtownbus bus
    2. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    4. Take the train from Fullerton Amtrak Station to San Diegotrain train
    3d
    $1,439–2,280

Boston to Santa Fe Depot by train (Amtrak)

Calendar7Weekly Trains
Duration2d 21hAverage Duration
Ticket$1,814Cheapest Price
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Comparing Your Travel Options

Map of how to get from Boston to Santa Fe Depot.ExpandLaunch map view
  • Distance: 2,589.9 mi
  • Duration: 8h 31m

What companies run services between Boston, MA, USA and Santa Fe Depot, San Diego County, CA, USA?

You can take a train from Boston to San Diego via Chicago Union Station and Fullerton Amtrak Station in around 2d 21h. Alternatively, you can take a bus from Boston to San Diego via Newark Penn Station, St Louis Bus Station, Los Angeles Union Station, and Los Angeles in around 3d 1h.

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