There are 6 ways to get from Boston to West Seneca by plane, bus, bus (Greyhound), train (Amtrak), car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Buffalo Niagara International Airport, line 15 bus
best- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane BOS - BUF
- Take the bus from Lower Terrace & Adams Mark to Seneca Street & Cazenovia Parkwaybus
3h 24m$92–552Bus (Greyhound)
cheapest- Take the bus from Boston to Buffalobus Greyhound US0171
10h 55m$76–139Train (Amtrak)
- Take the train from Boston to Buffalo Depew Stationtrain Lake Shore Limited
11h 51m$188–350Drive 453.3 mi
- Drive from Boston to West Senecacar 453.3 mi
7h 56m$83–120Fly to Rochester, bus
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane BOS - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
5h 5m$112–541Bus via Ithaca
- Take the bus from Boston to Ithacabus FlixBus 2691
- Take the bus from Ithaca to Buffalobus FlixBus N2687 / ...
13h 24m$89–198
Boston to West Seneca by bus (Greyhound)
Questions & Answers
The cheapest way to get from Boston to West Seneca is to bus which costs $75 - $140 and takes 10h 55m.
The fastest way to get from Boston to West Seneca is to fly and line 15 bus which takes 3h 24m and costs $90 - $550.
No, there is no direct bus from Boston to West Seneca. However, there are services departing from Boston and arriving at Abbott Road & Red Jacket Parkway via Washington Street & Eagle Street. The journey, including transfers, takes approximately 10h 55m.
No, there is no direct train from Boston to West Seneca station. However, there are services departing from Boston and arriving at Buffalo Depew Station via . The journey, including transfers, takes approximately 11h 51m.
The distance between Boston and West Seneca is 416 miles. The road distance is 455.9 miles.
The best way to get from Boston to West Seneca without a car is to bus which takes 10h 55m and costs $75 - $140.
It takes approximately 3h 24m to get from Boston to West Seneca, including transfers.
Boston to West Seneca bus services, operated by Greyhound USA, depart from Boston station.
Boston to West Seneca train services, operated by Amtrak, depart from Boston station.
The best way to get from Boston to West Seneca is to bus which takes 10h 55m and costs $75 - $140. Alternatively, you can train, which costs $180 - $350 and takes 11h 51m.
What companies run services between Boston, MA, USA and West Seneca, NY, USA?
Greyhound USA operates a bus from Boston to Buffalo once daily. Tickets cost $70–140 and the journey takes 10h 5m. Alternatively, Amtrak operates a train from Boston to Buffalo Depew Station once daily. Tickets cost $160–320 and the journey takes 11h 39m.
- Website
- aa.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $85–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 3h 58m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–600
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 4h 3m
- When
- Saturday
- Estimated price
- $95–550
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $80–500
- Website
- southwest.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 48m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $110–650
Flights from Boston Logan Airport to Rochester via Baltimore
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $110–600
- Website
- jetblue.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $85–550
- Website
- united.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 3h 53m
- When
- Monday to Friday
- Estimated price
- $95–550
Flights from Boston Logan Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 53m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–650
Flights from Boston Logan Airport to Rochester via Newark
- Ave. Duration
- 3h 58m
- When
- Monday and Saturday
- Estimated price
- $90–550
- Website
- delta.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
Flights from Boston Logan Airport to Rochester via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday to Friday
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Buffalo Depew Station
- Ave. Duration
- 11h 39m
- Frequency
- Once daily
- Estimated price
- $160–320
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 716-855-7211
- [email protected]
- Website
- metro.nfta.com
Bus from Lower Terrace & Adams Mark to Seneca Street & Cazenovia Parkway
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- $2
- Website
- https://metro.nfta.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Boston to Buffalo
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $70–140
- Website
- https://www.greyhound.com/
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- $11–22
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $11–19
- Schedules at
- flixbus.com
Bus from Boston to Ithaca
- Ave. Duration
- 7h 44m
- Frequency
- 3 times a week
- Estimated price
- $55–100
- Schedules at
- flixbus.com
Bus from Ithaca to Buffalo
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $25–45
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Ithaca to Buffalo
- Ave. Duration
- 3h 50m
- Frequency
- Twice daily
- Estimated price
- $28–100
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $28–95
- Flexible
- $55–100
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More Questions & Answers
Boston to West Seneca bus services, operated by Greyhound USA, arrive at Buffalo station.
Boston to West Seneca train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between Boston to West Seneca is 456 miles. It takes approximately 7h 56m to drive from Boston to West Seneca.
Book your Boston to West Seneca train tickets online with Omio.
There are 243+ hotels available in West Seneca.











