There are 7 ways to get from Boston to West Seneca by ferry, plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry to Boston Logan Airport, fly to Buffalo Niagara International Airport
best- Take the ferry from Long Wharf to Logan Airport Ferry Terminalferry
- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane BOS - BUF
5h 25m$91–590Bus (Greyhound)
cheapest- Take the bus from Boston to Buffalobus Greyhound US0171
11h 2m$77–119Train (Amtrak)
- Take the train from Boston to Buffalo Depew Stationtrain Lake Shore Limited
11h 51m$147–317Drive 453.3 mi
- Drive from Boston to West Senecacar 453.3 mi
7h 56m$83–120Ferry to Boston Logan Airport, fly to Rochester, bus
- Take the ferry from Long Wharf to Logan Airport Ferry Terminalferry
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane BOS - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
6h 55m$135–753Ferry to Provincetown Municipal Airport, fly to Buffalo Niagara International Airport
- Take the ferry from World Trade Center Pier, Boston, MA to MacMillan Pier, Provincetown, MAferry
- Fly from Provincetown Municipal Airport (PVC) to Buffalo Niagara International Airport (BUF)plane PVC - BUF
9h 3m$215–887Bus via Ithaca
- Take the bus from Boston to Ithacabus FlixBus 2691
- Take the bus from Ithaca to Buffalobus Adt N806-D / ...
13h 33m$82–126
Boston to West Seneca by bus and foot (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Boston to West Seneca is to bus which costs $75 - $120 and takes 11h 2m.
The fastest way to get from Boston to West Seneca is to ferry and fly which takes 5h 25m and costs $90 - $600.
No, there is no direct bus from Boston to West Seneca. However, there are services departing from Boston and arriving at Abbott Road & Red Jacket Parkway via Washington Street & Mohawk Street. The journey, including transfers, takes approximately 11h 2m.
No, there is no direct train from Boston to West Seneca station. However, there are services departing from Boston and arriving at Buffalo Depew Station via . The journey, including transfers, takes approximately 11h 51m.
The distance between Boston and West Seneca is 415 miles. The road distance is 455.9 miles.
The best way to get from Boston to West Seneca without a car is to bus which takes 11h 2m and costs $75 - $120.
It takes approximately 5h 25m to get from Boston to West Seneca, including transfers.
Boston to West Seneca bus services, operated by Greyhound USA, depart from Boston station.
Boston to West Seneca train services, operated by Amtrak, depart from Boston station.
The best way to get from Boston to West Seneca is to bus which takes 11h 2m and costs $75 - $120. Alternatively, you can train, which costs $140 - $320 and takes 11h 51m.
What companies run services between Boston, MA, USA and West Seneca, NY, USA?
Greyhound USA operates a bus from Boston to Buffalo once daily. Tickets cost $75–120 and the journey takes 10h 5m. Alternatively, Amtrak operates a train from Boston to Buffalo Depew Station once daily. Tickets cost $120–290 and the journey takes 11h 39m.
- Website
- aa.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $80–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- $90–550
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $100–700
Flights from Boston Logan Airport to Rochester via Philadelphia
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $120–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Buffalo Depew Station
- Ave. Duration
- 11h 39m
- Frequency
- Once daily
- Estimated price
- $120–290
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston to Buffalo
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- $11–19
- Website
- Greyhound
Ferry from Long Wharf to Logan Airport Ferry Terminal
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- $3–10
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–10
Ferry from Long Wharf to Logan Airport Ferry Terminal
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- $3–10
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–10
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Booking & Getting There
Boston to West Seneca bus services, operated by Greyhound USA, arrive at Buffalo station.
Boston to West Seneca train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between Boston to West Seneca is 456 miles. It takes approximately 7h 56m to drive from Boston to West Seneca.
Book your Boston to West Seneca train tickets online with Omio.
There are 261+ hotels available in West Seneca.








