There are 5 ways to get from Brainerd to Mayo Clinic by bus, taxi, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Perkins Restaurant & Bakery - Brainerd to Minneapolis / St Paul Airportbus Groome Transportation - Brainerd
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus Groome Transportation
6h 20m$110Drive 208.6 mi
cheapest- Drive from Brainerd to Mayo Cliniccar 208.6 mi
3h 57m$39–55Taxi, train, bus
- Take the taxi from Brainerd to Staples Stationtaxi
- Take the train from Staples Station to St. Paul-Minneapolistrain
- Take the bus from St. Paul to Rochester, MNbus
6h 24m$142–216Fly to Rochester
- Fly from Brainerd Lakes Regional Airport (BRD) to Rochester (RST)plane BRD - RST
5h 39m$59–342Fly to Minneapolis–Saint Paul International Airport, bus
- Fly from Brainerd Lakes Regional Airport (BRD) to Minneapolis–Saint Paul International Airport (MSP)plane BRD - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
4h 6m$110–394
Brainerd Lakes Regional Airport (BRD) to Rochester (RST) flights
Questions & Answers
The cheapest way to get from Brainerd to Mayo Clinic is to drive which costs $35 - $55 and takes 3h 57m.
The fastest way to get from Brainerd to Mayo Clinic is to drive which takes 3h 57m and costs $35 - $55.
No, there is no direct bus from Brainerd to Mayo Clinic. However, there are services departing from Perkins Restaurant & Bakery - Brainerd and arriving at Groome Transportation Office - Rochester via Minneapolis / St Paul Airport. The journey, including transfers, takes approximately 6h 20m.
The distance between Brainerd and Mayo Clinic is 225 miles. The road distance is 209.8 miles.
The best way to get from Brainerd to Mayo Clinic without a car is to bus which takes 6h 20m and costs $110.
It takes approximately 6h 20m to get from Brainerd to Mayo Clinic, including transfers.
Brainerd to Mayo Clinic bus services, operated by Groome Transportation, depart from Perkins Restaurant & Bakery - Brainerd station.
The best way to get from Brainerd to Mayo Clinic is to bus which takes 6h 20m and costs $110. Alternatively, you can fly, which costs $55 - $350 and takes 5h 39m.
Brainerd to Mayo Clinic bus services, operated by Groome Transportation, arrive at Minneapolis / St Paul Airport station.
Yes, the driving distance between Brainerd to Mayo Clinic is 210 miles. It takes approximately 3h 57m to drive from Brainerd to Mayo Clinic.
What companies run services between Brainerd, MN, USA and Mayo Clinic, MN, USA?
You can take a bus from Perkins Restaurant & Bakery - Brainerd to Mayo Clinic via Minneapolis / St Paul Airport and Groome Transportation Office - Rochester in around 6h 20m. Alternatively, Delta flies from Brainerd Lakes Regional Airport (BRD) to Rochester (RST) twice daily.
- Website
- delta.com
Flights from Brainerd Lakes Regional Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $40–280
Flights from Brainerd Lakes Regional Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 57 min
- When
- Every day
- Estimated price
- $40–320
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Staples Station to St. Paul-Minneapolis
- Ave. Duration
- 3h 6m
- Frequency
- Twice daily
- Estimated price
- $45–95
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 320-316-0943
- Website
- groometransportation.com
Bus from Perkins Restaurant & Bakery - Brainerd to Minneapolis / St Paul Airport
- Ave. Duration
- 3h 20m
- Frequency
- Every 4 hours
- Estimated price
- $60
- Schedules at
- groometransportation.com
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from St. Paul to Rochester, MN
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $28–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $28–40
- Ave. Duration
- 40 min
- Estimated price
- $65–85
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 73+ hotels available in Mayo Clinic.







