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How to get fromBrandon to Great Smoky Mountainsby car, plane, bus, or train

Find Transport to Great Smoky Mountains

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There are 9 ways to get from Brandon to Great Smoky Mountains by car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly to Mcghee Tyson Airport, drive

    best
    1. Drive from Brandon to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane plane SFB - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    5h 27m
    $148–742

  2. Fly Saint Petersburg–Clearwater International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Asheville Regional Airport (AVL)plane plane PIE - AVL
    2. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    7h 36m
    $84–392

  3. Bus, drive

    1. Take the bus from Tampa Bus Station to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    23h 19m
    $154–273

  4. Train, bus, drive

    1. Take the train from Tampa to Carytrain train
    2. Take the train from Cary to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    25h 54m
    $284–594

  5. Drive 624.2 mi

    1. Drive from Brandon to Great Smoky Mountainscar car 624.2 mi
    11h 36m
    $114–165

  6. Fly Tampa to Greenville–Spartanburg International Airport, drive

    1. Fly from Tampa (TPA) to Greenville–Spartanburg International Airport (GSP)plane plane TPA - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Great Smoky Mountainscar car
    7h 45m
    $105–261

  7. Fly Saint Petersburg–Clearwater International Airport to Mcghee Tyson Airport, drive

    1. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Mcghee Tyson Airport (TYS)plane plane PIE - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    7h 24m
    $140–726

  8. Fly Tampa to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Tampa (TPA) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane TPA - ATL
    2. Drive from Atlanta-Airport-ATL to Great Smoky Mountainscar car
    8h 29m
    $231–661

  9. Train to Orlando, fly to Mcghee Tyson Airport, drive

    1. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    2. Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane plane MCO - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    9h 3m
    $150–726

Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) flights

Calendar11Weekly Planes
Duration1h 38mAverage Duration
Ticket$120Cheapest Price
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Questions & Answers

Map of how to get from Brandon to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 667.6 mi
  • Duration: 5h 27m

What companies run services between Brandon, FL, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Brandon to Great Smoky Mountains. However, you can drive to Orlando-Sanford-Airport-SFB airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from Town Center Blvd @ Providence Rd to Great Smoky Mountains via Marion Transit Center, Tampa Bus Station, Orlando Bus Station, Raleigh Bus Station, and Asheville, NC in around 23h 19m.

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