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How to get fromBrantford to Knoxvilleby train, plane, bus, or car

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There are 10 ways to get from Brantford to Knoxville by train, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Toronto Island Airport, fly to Mcghee Tyson Airport

    best
    1. Take the train from Brantford to Toronto Union Stationtrain train
    2. Fly from Toronto Island Airport (YTZ) to Mcghee Tyson Airport (TYS)plane plane YTZ - TYS
    8h 14m
    $221–1,070

  2. Drive  675.9 mi

    cheapest
    1. Drive from Brantford to Knoxvillecar car 675.9 mi
    11h 33m
    $155–224

  3. Train, bus

    1. Take the train from Brantford to Aldershottrain train
    2. Take the train from Aldershot to New York Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    27h 18m
    $275–611

  4. Bus

    1. Take the bus from McMaster University to Erin Mills Transitway Stationbus bus 41 / ...
    2. Take the bus from Mississauga to New Yorkbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    27h 44m
    $262–582

  5. Train to Toronto Pearson International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Brantford to Toronto Union Stationtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Mcghee Tyson Airport (TYS)plane plane YYZ - TYS
    8h 13m
    $201–970

  6. Train to Detroit, fly to Mcghee Tyson Airport

    1. Take the train from Brantford to Windsortrain train
    2. Fly from Detroit (DTW) to Mcghee Tyson Airport (TYS)plane plane DTW - TYS
    7h 31m
    $261–1,208

  7. Train, bus to Buffalo Niagara International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Brantford to Aldershottrain train
    2. Take the train from Aldershot GO to Niagara Falls GOtrain train
    3. Take the bus from Niagara Falls to Buffalobus bus
    4. Fly from Buffalo Niagara International Airport (BUF) to Mcghee Tyson Airport (TYS)plane plane BUF - TYS
    10h 57m
    $245–1,293

  8. Train to Toronto Pearson International Airport, fly to Nashville, drive

    1. Take the train from Brantford to Toronto Union Stationtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Nashville (BNA)plane plane YYZ - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    8h 39m
    $156–1,600

  9. Bus, train

    1. Take the bus from Brantford Bus Terminal to Aldershot GO Busbus bus 15
    2. Take the train from Aldershot to New York Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    27h 46m
    $320–571

  10. Bus, train via Niagara Falls

    1. Take the bus from Brantford Bus Terminal to Aldershot GO Busbus bus 15
    2. Take the bus from Burlington GO Bus to Niagara Falls Bus Terminalbus bus 12
    3. Take the train from Niagara Falls to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus Nyc
    28h 46m
    $322–548

Toronto Island Airport (YTZ) to Mcghee Tyson Airport (TYS) flights

Calendar81Weekly Planes
Duration5h 52mAverage Duration
Ticket$159Cheapest Price
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Comparing Your Travel Options

Map of how to get from Brantford to Knoxville.ExpandLaunch map view
  • Distance: 667.4 mi
  • Duration: 8h 14m

What companies run services between Brantford, ON, Canada and Knoxville, TN, USA?

You can take a bus from Brantford Bus Terminal to Knoxville via McMaster University, Erin Mills Transitway Station, Erin Mills Station West Platform 4, Mississauga, New York, 42 St-Times Square, Canal St, New York, and Knoxville in around 27h 44m.

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