There are 10 ways to get from Brno to Karlsruhe by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Brno Hlavni Nadrazi to Wien Hbftrain Rj
- Take the train from Wien Hbf to Hanau Hbftrain Ice
- Take the train from Hanau Hauptbahnhof to Karlsruhe Hauptbahnhoftrain 12 / ...
10h 52m€156–342Bus
cheapest- Take the bus from Brno to Mannheim central bus stationbus N1309
- Take the bus from Mannheim central bus station to Karlsruhe central train stationbus FlixBus 108 / ...
11h 26m€68–103Drive 726 km
- Drive from Brno to Karlsruhecar 726 km
6h 11m€115–166Train to Vienna International Airport, fly to Stuttgart Airport, train
- Take the train from Brno Hlavni Nadrazi to Wien Hbftrain
- Fly from Vienna International Airport (VIE) to Stuttgart Airport (STR)plane VIE - STR
- Take the train from Stuttgart Hbf to Karlsruhe Hbftrain
6h 44m€88–304Bus, train
- Take the bus from Brno Hlavní Nádraží to Stuttgartbus Ivano-Frankivsk
- Take the train from Stuttgart Hbf to Karlsruhe Hbftrain Re
13h 29m€106–155Train via Prague
- Take the train from Brno Hlavni Nadrazi to Praha Hlavni Nadrazitrain Ic
- Take the train from Praha Hlavni Nadrazi to Karlsruhe Hbftrain Ec
14h 15m€192–286Train to Vienna International Airport, fly to Frankfurt, train
- Take the train from Brno Hlavni Nadrazi to Wien Hbftrain
- Fly from Vienna International Airport (VIE) to Frankfurt (FRA)plane VIE - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
7h 22m€87–217Train to Vienna International Airport, fly to Basel, train
- Take the train from Brno Hlavni Nadrazi to Wien Hbftrain
- Fly from Vienna International Airport (VIE) to Basel (BSL)plane VIE - BSL
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain
7h 54m€119–383Train to Václav Havel Airport Prague, fly to Frankfurt, train
- Take the train from Brno hl.n. to Praha hl.n.train
- Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane PRG - FRA
- Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain
8h 35m€82–184Train to Vienna International Airport, fly to Zurich Airport, train
- Take the train from Brno Hlavni Nadrazi to Wien Hbftrain
- Fly from Vienna International Airport (VIE) to Zurich Airport (ZRH)plane VIE - ZRH
- Take the train from Zürich HB to Basel SBBtrain
- Take the train from Basel SBB to Karlsruhe Hauptbahnhoftrain
9h€165–396
Brno to Karlsruhe by train
Comparing Your Travel Options
The cheapest way to get from Brno to Karlsruhe is to bus which costs €65 - €110 and takes 11h 26m.
The fastest way to get from Brno to Karlsruhe is to drive which takes 6h 11m and costs €110 - €170.
No, there is no direct bus from Brno to Karlsruhe station. However, there are services departing from Brno and arriving at Karlsruhe central train station via Mannheim central bus station. The journey, including transfers, takes approximately 11h 26m.
No, there is no direct train from Brno to Karlsruhe. However, there are services departing from Brno Hlavni Nadrazi and arriving at Karlsruhe Hauptbahnhof via Wien Hbf and Hanau Hauptbahnhof. The journey, including transfers, takes approximately 10h 52m.
The distance between Brno and Karlsruhe is 1017 km. The road distance is 726 km.
The best way to get from Brno to Karlsruhe without a car is to train which takes 10h 52m and costs €150 - €350.
It takes approximately 10h 52m to get from Brno to Karlsruhe, including transfers.
Brno to Karlsruhe bus services, operated by FlixBus, depart from Brno station.
Brno to Karlsruhe train services, operated by České dráhy (ČD), depart from Brno Hlavni Nadrazi station.
The best way to get from Brno to Karlsruhe is to train which takes 10h 52m and costs €150 - €350. Alternatively, you can bus, which costs €65 - €110 and takes 11h 26m.
What companies run services between Brno, Czechia and Karlsruhe, Germany?
You can take a train from Brno Hlavni Nadrazi to Karlsruhe Hauptbahnhof via Wien Hbf, Hanau Hbf, and Hanau Hauptbahnhof in around 10h 52m. Alternatively, you can take a bus from Brno to Karlsruhe central train station via Mannheim central bus station in around 11h 26m.
- Website
- lufthansa.com
Flights from Vienna International Airport to Stuttgart Airport via Munich
- Ave. Duration
- 2h 59m
- When
- Every day
- Estimated price
- €65–190
Flights from Vienna International Airport to Frankfurt
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- €70–190
Flights from Vienna International Airport to Basel via Munich
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- €100–370
Flights from Vienna International Airport to Basel via Frankfurt
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €100–370
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €55–360
Flights from Václav Havel Airport Prague to Frankfurt via Munich
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- €55–140
Flights from Vienna International Airport to Zurich Airport via Munich
- Ave. Duration
- 2h 50m
- When
- Monday to Saturday
- Estimated price
- €90–220
- Website
- austrian.com
Flights from Vienna International Airport to Stuttgart Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €65–200
Flights from Vienna International Airport to Frankfurt
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- €70–190
Flights from Vienna International Airport to Basel
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €100–370
Flights from Vienna International Airport to Zurich Airport
- Ave. Duration
- 1h 21m
- When
- Every day
- Estimated price
- €90–220
- Website
- swiss.com
Flights from Vienna International Airport to Stuttgart Airport via Zurich Airport
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €65–190
Flights from Vienna International Airport to Basel
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €100–370
Flights from Vienna International Airport to Zurich Airport
- Ave. Duration
- 1h 21m
- When
- Every day
- Estimated price
- €90–220
- Website
- condor.com
Flights from Vienna International Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €65–130
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 1m
- When
- Every day
- Estimated price
- €55–110
- Website
- eurowings.com
Flights from Vienna International Airport to Stuttgart Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €65–200
- Website
- easyjet.com
Flights from Vienna International Airport to Basel
- Ave. Duration
- 1h 25m
- When
- Saturday
- Estimated price
- €80–260
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €120–360
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Brno Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 1h 31m
- Frequency
- Every 4 hours
- Estimated price
- €12
- Website
- Czech Railways (ČD)
Train from Brno Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 1h 31m
- Frequency
- Every 4 hours
- Estimated price
- €12
- Website
- Czech Railways (ČD)
Train from Brno Hlavni Nadrazi to Praha Hlavni Nadrazi
- Ave. Duration
- 3h 10m
- Frequency
- Every 30 minutes
- Estimated price
- €20
- Website
- Czech Railways (ČD)
Train from Brno Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 1h 31m
- Frequency
- Every 4 hours
- Estimated price
- €12
- Website
- Czech Railways (ČD)
Train from Brno Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 1h 31m
- Frequency
- Every 4 hours
- Estimated price
- €12
- Website
- Czech Railways (ČD)
Train from Brno Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 1h 31m
- Frequency
- Every 4 hours
- Estimated price
- €12
- Website
- Czech Railways (ČD)
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Train from Brno Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- €7–12
- Website
- RegioJet
Train from Brno Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- €7–12
- Website
- RegioJet
Train from Brno Hlavni Nadrazi to Praha Hlavni Nadrazi
- Ave. Duration
- 2h 42m
- Frequency
- Hourly
- Estimated price
- €12–21
- Website
- RegioJet
Train from Brno Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- €7–12
- Website
- RegioJet
Train from Brno Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- €7–12
- Website
- RegioJet
Train from Brno hl.n. to Praha hl.n.
- Ave. Duration
- 2h 40m
- Frequency
- 4 times a day
- Estimated price
- €12–21
- Website
- RegioJet
Train from Brno Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- €7–12
- Website
- RegioJet
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Wien Hbf to Hanau Hbf
- Ave. Duration
- 6h 4m
- Frequency
- Every 4 hours
- Estimated price
- €120–270
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Hanau Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 29m
- Frequency
- Hourly
- Estimated price
- €29–60
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €14–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €14–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €24–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €35–75
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 8m
- Frequency
- Every 3 hours
- Estimated price
- €24–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €35–75
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +43 5 1717
- Website
- Österreichische Bundesbahnen
Train from Hanau Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- €35–55
- Website
- Österreichische Bundesbahnen
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- €12–55
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- €12–55
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Brno Hlavni Nadrazi to Praha Hlavni Nadrazi
- Ave. Duration
- 2h 37m
- Frequency
- Every 4 hours
- Estimated price
- €55–70
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Karlsruhe Hbf
- Ave. Duration
- 10h 33m
- Frequency
- 3 times a day
- Estimated price
- €180–220
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +36 (1) 3 49 49 49
- [email protected]
- Website
- Hungarian Railways (MÁV)
Train from Brno Hlavni Nadrazi to Praha Hlavni Nadrazi
- Ave. Duration
- 2h 37m
- Frequency
- 4 times a day
- Estimated price
- €12–14
- Website
- Hungarian Railways (MÁV)
- Phone
- +421 24 48 58 188
- [email protected]
- Website
- Railways of Slovak Republic (ZSSK)
Train from Brno Hlavni Nadrazi to Praha Hlavni Nadrazi
- Ave. Duration
- 2h 37m
- Frequency
- Twice daily
- Estimated price
- €12–22
- Website
- Railways of Slovak Republic (ZSSK)
Train from Brno hl.n. to Praha hl.n.
- Ave. Duration
- 2h 37m
- Frequency
- Every 4 hours
- Estimated price
- €12–22
- Website
- Railways of Slovak Republic (ZSSK)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 53m
- Frequency
- Twice daily
- Estimated price
- €14–29
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 53m
- Frequency
- Twice daily
- Estimated price
- €14–29
- Website
- Nederlandse Spoorwegen (NS)
Train from Zürich HB to Basel SBB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €29–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Brno to Mannheim central bus station
- Ave. Duration
- 9h 50m
- Frequency
- Once daily
- Estimated price
- €60–95
- Website
- Flixbus
Bus from Mannheim central bus station to Karlsruhe central train station
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- €6–10
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Mannheim central bus station to Karlsruhe central train station
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- €5–9
- Website
- BlaBlaCar Bus
- Phone
- +371 67 214 512
- [email protected]
- Website
- ecolines.net
Bus from Mannheim central bus station to Karlsruhe central train station
- Ave. Duration
- 1h
- Frequency
- 6 times a week
- Estimated price
- €5–10
- Schedules at
- ecolines.net
- Phone
- +38 098-888-11-08
- [email protected]
- Website
- Grand Bus
Bus from Brno Hlavní Nádraží to Stuttgart
- Ave. Duration
- 12h 26m
- Frequency
- Once daily
- Estimated price
- €90–105
- Website
- Grand Bus
Want to know more about travelling around Germany
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Booking & Getting There
Brno to Karlsruhe bus services, operated by FlixBus, arrive at Mannheim central bus station.
Brno to Karlsruhe train services, operated by České dráhy (ČD), arrive at Wien Hbf station.
Yes, the driving distance between Brno to Karlsruhe is 726 km. It takes approximately 6h 11m to drive from Brno to Karlsruhe.
Book your Brno to Karlsruhe train tickets online with Omio.
Book your Brno to Karlsruhe bus tickets online with Omio and FlixBus.
There are 900+ hotels available in Karlsruhe.

































































