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How to get fromBrno to Sienaby train, plane, train (Trenitalia), bus, night train, or car

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There are 8 ways to get from Brno to Siena by train, plane, train (Trenitalia), bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, fly to Florence Peretola Airport

    best
    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train
    2. Fly from Vienna International Airport (VIE) to Florence Peretola Airport (FLR)plane plane VIE - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 28m
    €109–341

  2. Bus

    cheapest
    1. Take the bus from Brno Benesova Bus Station to Florence Villa Constanza Bus Stationbus bus : Prague Central Bus Station - Rome Tiburtina Bus Station / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    15h 20m
    €71–102

  3. Train

    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train Rj
    2. Take the train from Wien Hbf to Venezia Mestretrain train Rjx
    3. Take the train from Venezia Mestre to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    13h 51m
    €140–254

  4. Train, night train

    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train Rj
    2. Take the nighttrain from Wien Hbf to Firenze Campo Martenighttrain night train Nj
    3. Take the train from Firenze S.M.N. to Sienatrain train Re
    15h 24m
    €71–175

  5. Train, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train
    2. Fly from Vienna International Airport (VIE) to Bologna Guglielmo Marconi Airport (BLQ)plane plane VIE - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    8h 3m
    €72–296

  6. Train, fly to Venice Marco Polo Airport

    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train
    2. Fly from Vienna International Airport (VIE) to Venice Marco Polo Airport (VCE)plane plane VIE - VCE
    3. Take the train from Venezia Mestre to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    9h 50m
    €83–281

  7. Train, bus

    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train Rj
    2. Take the bus from Vienna, Central Station Südtiroler Platz to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    17h 26m
    €74–143

  8. Drive  991.9 km

    1. Drive from Brno to Sienacar car 991.9 km
    10h 24m
    €157–226

Brno to Siena by train

Calendar28Weekly Trains
Duration13h 51mAverage Duration
Ticket€140Cheapest Price
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Questions & Answers

Map of how to get from Brno to Siena.ExpandLaunch map view
  • Distance: 897.9 km
  • Duration: 7h 28m

What companies run services between Brno, Czechia and Siena, Italy?

You can take a train from Brno Hlavni Nadrazi to Siena via Wien Hbf, Venezia Mestre, and Firenze S.M.N. in around 13h 51m. Alternatively, you can take a bus from Brno Benesova Bus Station to Siena via Florence Villa Constanza Bus Station in around 15h 20m.

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