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How to get fromBrno to Sienaby train, plane, train (Trenitalia), bus, night train, or car

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There are 10 ways to get from Brno to Siena by train, plane, train (Trenitalia), bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Vienna International Airport, fly to Florence Peretola Airport, train

    best
    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train
    2. Fly from Vienna International Airport (VIE) to Florence Peretola Airport (FLR)plane plane VIE - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 3m
    €111–353

  2. Train, night train, bus

    cheapest
    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train Rj
    2. Take the nighttrain from Wien Hbf to Firenze Campo Martenighttrain night train Nj
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    15h 12m
    €63–157

  3. Train

    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train Rj
    2. Take the train from Wien Hbf to Venezia Mestretrain train Rjx
    3. Take the train from Venezia Mestre to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    14h 39m
    €137–236

  4. Bus

    1. Take the bus from Brno Benesova Bus Station to Florence Villa Constanza Bus Stationbus bus : Prague Central Bus Station - Rome Tiburtina Bus Station / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 1518 / ...
    15h 20m
    €64–104

  5. Train to Vienna International Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train
    2. Fly from Vienna International Airport (VIE) to Bologna Guglielmo Marconi Airport (BLQ)plane plane VIE - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    8h 36m
    €73–283

  6. Train to Václav Havel Airport Prague, fly to Pisa International Airport, train

    1. Take the train from Brno hl.n. to Praha hl.n.train train
    2. Fly from Václav Havel Airport Prague (PRG) to Pisa International Airport (PSA)plane plane PRG - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    9h 43m
    €90–290

  7. Train to Vienna International Airport, fly to Venice Marco Polo Airport, train

    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train
    2. Fly from Vienna International Airport (VIE) to Venice Marco Polo Airport (VCE)plane plane VIE - VCE
    3. Take the train from Venezia Mestre to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    10h 41m
    €84–283

  8. Train to Vienna International Airport, fly to Fiumicino International Airport, train

    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train
    2. Fly from Vienna International Airport (VIE) to Fiumicino International Airport (FCO)plane plane VIE - FCO
    3. Take the train from Roma Termini to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    10h 29m
    €95–292

  9. Bus via Vienna

    1. Take the bus from Brno to Vienna, International Busterminal (VIB)bus bus 919 / ...
    2. Take the bus from Vienna, International Busterminal (VIB) to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    18h 5m
    €87–136

  10. Drive  991.9 km

    1. Drive from Brno to Sienacar car 991.9 km
    10h 27m
    €161–232

Brno to Siena by train

Calendar14Weekly Trains
Duration14h 39mAverage Duration
Ticket€137Cheapest Price
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Comparing Your Travel Options

Map of how to get from Brno to Siena.ExpandLaunch map view
  • Distance: 897.9 km
  • Duration: 8h 3m

What companies run services between Brno, Czechia and Siena, Italy?

You can take a train from Brno Hlavni Nadrazi to Siena via Wien Hbf, Venezia Mestre, and Firenze S.M.N. in around 14h 39m. Alternatively, you can take a bus from Brno Benesova Bus Station to Siena via Florence Villa Constanza Bus Station in around 15h 20m.

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