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How to get fromBrno to Sienaby train, plane, train (Trenitalia), bus, night train, or car

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There are 8 ways to get from Brno to Siena by train, plane, train (Trenitalia), bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, fly to Florence Peretola Airport

    best
    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train
    2. Fly from Vienna International Airport (VIE) to Florence Peretola Airport (FLR)plane plane VIE - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 40m
    €114–302

  2. Train, fly to Bologna Guglielmo Marconi Airport

    cheapest
    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train
    2. Fly from Vienna International Airport (VIE) to Bologna Guglielmo Marconi Airport (BLQ)plane plane VIE - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    8h 6m
    €61–247

  3. Train

    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train Rj
    2. Take the train from Wien Hbf to Venezia Mestretrain train Rjx
    3. Take the train from Venezia Mestre to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    13h 51m
    €140–255

  4. Bus

    1. Take the bus from Brno Benesova Bus Station to Florence Villa Constanza Bus Stationbus bus : Prague Central Bus Station - Rome Tiburtina Bus Station / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    15h 18m
    €79–114

  5. Train, night train

    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train Rj
    2. Take the night train from Wien Hbf to Firenze Campo Martenighttrain night train Nj
    3. Take the train from Firenze S.M.N. to Sienatrain train Re
    15h 23m
    €71–176

  6. Train, fly to Venice Marco Polo Airport

    1. Take the train from Brno Hlavni Nadrazi to Wien Hbftrain train
    2. Fly from Vienna International Airport (VIE) to Venice Marco Polo Airport (VCE)plane plane VIE - VCE
    3. Take the train from Venezia Mestre to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    9h 53m
    €79–272

  7. Bus via Bologna

    1. Take the bus from Brno to Bologna Centralebus bus N1284
    2. Take the bus from Bologna Centrale to Sienabus bus N597 / ...
    18h 5m
    €92–152

  8. Drive 992.4 km

    1. Drive from Brno to Sienacar car 992.4 km
    10h 23m
    €156–225

Brno to Siena by train

Calendar28Weekly Trains
Duration13h 51mAverage Duration
Ticket€140Cheapest Price
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Questions & Answers

Map of how to get from Brno to Siena.ExpandLaunch map view
  • Distance: 897.9 km
  • Duration: 7h 40m

What companies run services between Brno, Czechia and Siena, Italy?

You can take a train from Brno Hlavni Nadrazi to Siena via Wien Hbf, Venezia Mestre, and Firenze S.M.N. in around 13h 51m. Alternatively, you can take a bus from Brno Benesova Bus Station to Siena via Florence Villa Constanza Bus Station in around 15h 18m.

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