There are 5 ways to get from Brookings to Des Moines by bus (Greyhound), car, bus, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Brookings to Sioux Fallsbus
- Take the bus from Sioux Falls to Omahabus
- Take the bus from Omaha, NE to Des Moinesbus
8h 44m$99–158Drive 336.7 mi
cheapest- Drive from Brookings to Des Moinescar 336.7 mi
5h 15m$62–89Bus to Sioux Falls, fly
- Take the bus from Brookings to Sioux Fallsbus
- Fly from Sioux Falls (FSD) to Des Moines (DSM)plane FSD - DSM
5h 38m$153–629Bus to Watertown Municipal Airport, fly
- Take the bus from Brookings to Watertownbus
- Fly from Watertown Municipal Airport (ATY) to Des Moines (DSM)plane ATY - DSM
5h 55m$150–632Drive to Aberdeen Regional Airport, fly
- Drive from Brookings to Aberdeen Regional Airport (ABR)car
- Fly from Aberdeen Regional Airport (ABR) to Des Moines (DSM)plane ABR - DSM
6h 24m$143–659
Sioux Falls (FSD) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Brookings to Des Moines is to drive which costs $60 - $90 and takes 5h 15m.
The fastest way to get from Brookings to Des Moines is to drive which takes 5h 15m and costs $60 - $90.
No, there is no direct bus from Brookings to Des Moines. However, there are services departing from Brookings and arriving at Des Moines via Sioux Falls and Omaha, NE. The journey, including transfers, takes approximately 8h 44m.
The distance between Brookings and Des Moines is 387 miles. The road distance is 338.7 miles.
The best way to get from Brookings to Des Moines without a car is to bus which takes 8h 44m and costs $95 - $160.
It takes approximately 8h 44m to get from Brookings to Des Moines, including transfers.
Brookings to Des Moines bus services, operated by Jefferson Lines, depart from Brookings station.
Brookings to Des Moines bus services, operated by Jefferson Lines, arrive at Sioux Falls station.
Yes, the driving distance between Brookings to Des Moines is 339 miles. It takes approximately 5h 15m to drive from Brookings to Des Moines.
There are 260+ hotels available in Des Moines.
What companies run services between Brookings, SD, USA and Des Moines, IA, USA?
You can take a vehicle from Brookings to Des Moines via Brookings, Sioux Falls, and Omaha, NE in around 8h 44m.
- Website
- delta.com
Flights from Sioux Falls to Des Moines via Minneapolis
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $95–550
Flights from Watertown Municipal Airport to Des Moines via Minneapolis
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $90–550
Flights from Aberdeen Regional Airport to Des Moines via Minneapolis
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $100–600
- Website
- united.com
Flights from Sioux Falls to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $130–700
Flights from Sioux Falls to Des Moines via Denver
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $160–800
Flights from Watertown Municipal Airport to Des Moines via Denver
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $170–800
- Website
- aa.com
Flights from Sioux Falls to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $200–900
Flights from Sioux Falls to Des Moines via Chicago O'Hare
- Ave. Duration
- 7h 1m
- When
- Every day
- Estimated price
- $130–700
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Brookings to Sioux Falls
- Ave. Duration
- 50 min
- Frequency
- 5 times a week
- Estimated price
- $23–35
- Book at
- Jefferson Lines
- Adult
- $23–35
Bus from Sioux Falls to Omaha
- Ave. Duration
- 3h 35m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Brookings to Sioux Falls
- Ave. Duration
- 50 min
- Frequency
- 5 times a week
- Estimated price
- $23–35
- Book at
- Jefferson Lines
- Adult
- $23–35
Bus from Brookings to Watertown
- Ave. Duration
- 55 min
- Frequency
- 5 times a week
- Estimated price
- $22–35
- Book at
- Jefferson Lines
- Adult
- $22–35
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Omaha, NE to Des Moines
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- $20–40
- Website
- Greyhound
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