There are 7 ways to get from Brookline to Syracuse by plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, bus, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Syracuse Hancock International Airport
best- Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane BOS - SYR
4h 21m$95–567Bus
cheapest- Take the bus from Boston to Syracuse Bus Stationbus Greyhound US0171 / ...
7h 46m$47–99Train (Amtrak)
- Take the train from Boston to Syracuse Regional Transportation Centertrain Lake Shore Limited
8h 54m$110–230Drive 306.7 mi
- Drive from Brookline to Syracusecar 306.7 mi
5h 25m$56–81Fly to Rochester, train
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane BOS - ROC
- Take the train from Rochester to Syracuse Regional Transportation Centertrain
5h 18m$133–751Fly to Buffalo Niagara International Airport, bus
- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane BOS - BUF
- Take the bus from Buffalo Niagara International Airport to Syracuse Bus Stationbus
6h 25m$116–599Bus via West Albany
- Take the bus from Boston to Albanybus FlixBus 2691
- Take the bus from Albany to Syracusebus Adt A264
9h 13m$53–92
Brookline to Syracuse by bus
Questions & Answers
The cheapest way to get from Brookline to Syracuse is to bus which costs $45 - $100 and takes 7h 46m.
The fastest way to get from Brookline to Syracuse is to fly which takes 4h 21m and costs $95 - $600.
No, there is no direct bus from Brookline to Syracuse station. However, there are services departing from Nubian and arriving at Syracuse Bus Station via Boston. The journey, including transfers, takes approximately 7h 46m.
Yes, there is a direct train departing from Boston and arriving at Syracuse Regional Transportation Center. Services depart once daily, and operate every day. The journey takes approximately 8h 54m.
The distance between Brookline and Syracuse is 282 miles. The road distance is 308.4 miles.
The best way to get from Brookline to Syracuse without a car is to bus which takes 7h 46m and costs $45 - $100.
It takes approximately 4h 21m to get from Brookline to Syracuse, including transfers.
Brookline to Syracuse bus services, operated by Greyhound USA, depart from Boston station.
Brookline to Syracuse train services, operated by Amtrak, depart from Boston station.
The best way to get from Brookline to Syracuse is to fly which takes 4h 21m and costs $95 - $600. Alternatively, you can bus, which costs $45 - $100 and takes 7h 46m, you could also train, which costs $110 - $230 and takes 8h 54m.
What companies run services between Brookline, MA, USA and Syracuse, NY, USA?
American Airlines and JetBlue Airways fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR) twice daily. Alternatively, Greyhound USA operates a bus from Boston to Syracuse Bus Station 4 times a day. Tickets cost $45–95 and the journey takes 6h 25m. Flixbus USA also services this route 6 times a week.
- Website
- aa.com
Flights from Boston Logan Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $85–550
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $85–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $80–500
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 3h 58m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 4h 3m
- When
- Saturday
- Estimated price
- $90–550
- Website
- southwest.com
Flights from Boston Logan Airport to Rochester via Baltimore
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $120–650
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 48m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $110–600
- Website
- jetblue.com
Flights from Boston Logan Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $85–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $80–500
- Website
- united.com
Flights from Boston Logan Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 53m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–700
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $90–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 3m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–600
- Website
- delta.com
Flights from Boston Logan Airport to Rochester via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday to Friday
- Estimated price
- $95–600
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Syracuse Regional Transportation Center
- Ave. Duration
- 8h 54m
- Frequency
- Once daily
- Estimated price
- $110–230
- Website
- Amtrak
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $25–55
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–160
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–90
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 25m
- Frequency
- 4 times a day
- Estimated price
- $45–95
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 30m
- Frequency
- 6 times a week
- Estimated price
- $50–85
- Schedules at
- Flixbus USA
Bus from Buffalo Niagara International Airport to Syracuse Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- Every 2 hours
- Estimated price
- $24–40
- Schedules at
- Flixbus USA
Bus from Boston to Albany
- Ave. Duration
- 3h 50m
- Frequency
- 6 times a week
- Estimated price
- $28–50
- Schedules at
- Flixbus USA
Bus from Albany to Syracuse
- Ave. Duration
- 2h 35m
- Frequency
- 6 times a week
- Estimated price
- $23–40
- Schedules at
- Flixbus USA
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Buffalo Niagara International Airport to Syracuse Bus Station
- Saver
- $27–85
- Flexible
- $50–90
Bus from Albany to Syracuse
- Saver
- $26–85
- Flexible
- $50–90
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More Questions & Answers
Brookline to Syracuse bus services, operated by Greyhound USA, arrive at Syracuse Bus Station.
Brookline to Syracuse train services, operated by Amtrak, arrive at Syracuse Regional Transportation Center station.
Yes, the driving distance between Brookline to Syracuse is 308 miles. It takes approximately 5h 25m to drive from Brookline to Syracuse.
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