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How to get fromBrooksville to Florida Keysby car, plane, train, bus, shuttle, taxi, or bus (Greyhound)

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There are 12 ways to get from Brooksville to Florida Keys by car, plane, train, bus, shuttle, taxi, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly to Key West International Airport

    best
    1. Drive from Brooksville to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    6h 3m
    $128–387

  2. Drive  401.4 mi

    cheapest
    1. Drive from Brooksville to Florida Keyscar car 401.4 mi
    8h 14m
    $74–106

  3. Drive, train, bus

    1. Drive from Brooksville to Lakelandcar car
    2. Take the train from Lakeland to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    12h 14m
    $105–207

  4. Bus, shuttle to Tampa, fly to Key West International Airport

    1. Take the bus from Brooksville City Hall to Walmart at Cortez Blvd/SR50bus bus
    2. Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminalshuttle bus
    3. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    4. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    7h 47m
    $163–475

  5. Taxi, shuttle to Orlando, fly to Key West International Airport

    1. Take the taxi from Brooksville to Sleep Inn and Suites Wildwood-The Villagestaxi taxi
    2. Take a shuttle bus from Sleep Inn and Suites Wildwood-The Villages to Orlando Airportshuttle bus
    3. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    7h 10m
    $291–960

  6. Shuttle to Tampa, fly to Miami International Airport, shuttle

    1. Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminalshuttle bus
    2. Fly from Tampa (TPA) to Miami International Airport (MIA)plane plane TPA - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 17m
    $838–1,335

  7. Taxi, shuttle to Orlando, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the taxi from Brooksville to Sleep Inn and Suites Wildwood-The Villagestaxi taxi
    2. Take a shuttle bus from Sleep Inn and Suites Wildwood-The Villages to Orlando Airportshuttle bus
    3. Fly from Orlando (MCO) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane MCO - FLL
    4. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    10h
    $581–970

  8. Bus, shuttle, line 300 bus to Saint Petersburg–Clearwater International Airport, fly to Key West International Airport

    1. Take the bus from Brooksville City Hall to Walmart at Cortez Blvd/SR50bus bus
    2. Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminalshuttle bus
    3. Take the bus from Tpa Rental Car Facility to Psta 34Th St Complex - Shelter - Dbus bus
    4. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane plane PIE - EYW
    5. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    9h 43m
    $154–411

  9. Shuttle to Tampa, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminalshuttle bus
    2. Fly from Tampa (TPA) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane TPA - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 47m
    $308–535

  10. Bus

    1. Take the bus from Dade City to Miamibus bus Houston
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    14h 12m
    $158–214

  11. Taxi, bus

    1. Take the taxi from Brooksville to Wiregrass Park n Ridetaxi taxi
    2. Take the bus from Tampa Bus Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    15h 32m
    $135–200

  12. Shuttle, bus

    1. Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminalshuttle bus
    2. Take the bus from University of South Florida - 3801 USF Holly Dr to Miami Airportbus bus
    3. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus
    16h 25m
    $281–360

Orlando Sanford (SFB) to Key West International Airport (EYW) flights

Calendar4Weekly Planes
Duration1h 14mAverage Duration
Ticket$39Cheapest Price
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Comparing Your Travel Options

Map of how to get from Brooksville to Florida Keys.ExpandLaunch map view
  • Distance: 400.7 mi
  • Duration: 6h 3m

What companies run services between Brooksville, FL, USA and Florida Keys, FL, USA?

You can take a vehicle from Brooksville to Florida Keys via Dade City, Miami, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 14h 12m.

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