There are 9 ways to get from Brownsville to Florida Keys by plane, bus (Greyhound), car, bus, shuttle, ferry, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Brownsville-South Padre Island International Airport to Key West International Airport
best- Fly from Brownsville-South Padre Island International Airport (BRO) to Key West International Airport (EYW)plane BRO - EYW
13h 4m$169–516Bus
- Take the bus from Brownsville Bus Station to Houston - Harrisburg Blvdbus
- Take the bus from Houston - Harrisburg Blvd to Miamibus
- Take the bus from Miami Airport Station to Big Pine Keybus
38h 3m$289–394Drive 1,662.4 mi
- Drive from Brownsville to Florida Keyscar 1,662.4 mi
29h 38m$304–439Bus to Mcallen Miller International Airport, fly to Key West International Airport
- Take the bus from Brownsville to McAllen Central Stationbus
- Fly from Mcallen Miller International Airport (MFE) to Key West International Airport (EYW)plane MFE - EYW
11h 18m$224–805Fly Brownsville-South Padre Island International Airport to Miami International Airport, shuttle
- Fly from Brownsville-South Padre Island International Airport (BRO) to Miami International Airport (MIA)plane BRO - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
12h$284–616Bus to Rio Grande Valley International Airport, fly to Key West International Airport
- Take the bus from Brownsville to Harlingen Bus Stationbus
- Fly from Rio Grande Valley International Airport (HRL) to Key West International Airport (EYW)plane HRL - EYW
12h 5m$208–555Bus to Rio Grande Valley International Airport, fly to Miami International Airport, shuttle
- Take the bus from Brownsville to Harlingen Bus Stationbus
- Fly from Rio Grande Valley International Airport (HRL) to Miami International Airport (MIA)plane HRL - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
12h 36m$303–735Fly Brownsville-South Padre Island International Airport to Ft. Myers, ferry
- Fly from Brownsville-South Padre Island International Airport (BRO) to Ft. Myers (RSW)plane BRO - RSW
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry
15h 29m$278–732Bus via Houston
- Take the bus from La Plaza at Brownsville to Houston Bus Stationbus
- Take the bus from Houston - Harrisburg Blvd to Miamibus
- Take the bus from Miami Airport Station to Big Pine Keybus
39h 8m$275–417
Brownsville-South Padre Island International Airport (BRO) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Brownsville to Florida Keys is to fly which costs $160 - $550 and takes 13h 4m.
The fastest way to get from Brownsville to Florida Keys is to bus and fly which takes 11h 18m and costs $220 - $850.
No, there is no direct bus from Brownsville station to Florida Keys. However, there are services departing from Brownsville Bus Station and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Houston - Harrisburg Blvd, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 38h 3m.
The distance between Brownsville and Florida Keys is 1016 miles. The road distance is 1672.1 miles.
The best way to get from Brownsville to Florida Keys without a car is to bus which takes 38h 3m and costs $280 - $400.
It takes approximately 13h 4m to get from Brownsville to Florida Keys, including transfers.
Brownsville to Florida Keys bus services, operated by Omnibus Express, depart from Brownsville Bus Station.
The best way to get from Brownsville to Florida Keys is to fly which takes 13h 4m and costs $160 - $550. Alternatively, you can bus, which costs $280 - $400 and takes 38h 3m.
Brownsville to Florida Keys bus services, operated by Omnibus Express, arrive at Houston - Harrisburg Blvd station.
Yes, the driving distance between Brownsville to Florida Keys is 1672 miles. It takes approximately 29h 38m to drive from Brownsville to Florida Keys.
What companies run services between Brownsville, TX, USA and Florida Keys, FL, USA?
American Airlines, United Airlines, and Breeze Airways fly from Brownsville-South Padre Island International Airport (BRO) to Key West International Airport (EYW) once daily. Alternatively, you can take a bus from Brownsville Bus Station to Florida Keys via Houston - Harrisburg Blvd, Miami, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 38h 3m.
- Website
- aa.com
Flights from Brownsville-South Padre Island International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 10h 9m
- When
- Every day
- Estimated price
- $100–460
Flights from Mcallen Miller International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 30m
- When
- Every day
- Estimated price
- $140–650
Flights from Brownsville-South Padre Island International Airport to Miami International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 31m
- When
- Every day
- Estimated price
- $130–600
Flights from Brownsville-South Padre Island International Airport to Miami International Airport via Houston
- Ave. Duration
- 5h 10m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $110–550
Flights from Rio Grande Valley International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 9h 58m
- When
- Every day
- Estimated price
- $100–450
Flights from Rio Grande Valley International Airport to Miami International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 17m
- When
- Every day
- Estimated price
- $130–600
Flights from Brownsville-South Padre Island International Airport to Ft. Myers via Dallas/Ft.Worth
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $140–650
- Website
- united.com
Flights from Brownsville-South Padre Island International Airport to Miami International Airport via Houston
- Ave. Duration
- 7h 32m
- When
- Every day
- Estimated price
- $110–550
Flights from Rio Grande Valley International Airport to Miami International Airport via Houston
- Ave. Duration
- 7h 37m
- When
- Every day
- Estimated price
- $110–550
Flights from Brownsville-South Padre Island International Airport to Ft. Myers via Houston
- Ave. Duration
- 5h 35m
- When
- Every day
- Estimated price
- $110–550
- Website
- southwest.com
Flights from Rio Grande Valley International Airport to Miami International Airport via Houston Hobby Apt
- Ave. Duration
- 5h 42m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $110–500
Flights from Rio Grande Valley International Airport to Miami International Airport via Austin
- Ave. Duration
- 8h 7m
- When
- Monday to Saturday
- Estimated price
- $110–550
- Website
- flybreeze.com
Flights from Brownsville-South Padre Island International Airport to Key West International Airport via Houston, Tampa
- Ave. Duration
- 8h 53m
- When
- Thursday and Sunday
- Estimated price
- $90–420
Flights from Rio Grande Valley International Airport to Key West International Airport via Houston Hobby Apt, Tampa
- Ave. Duration
- 6h 33m
- When
- Sunday
- Estimated price
- $90–410
- Website
- flyfrontier.com
Flights from Brownsville-South Padre Island International Airport to Miami International Airport via Houston
- Ave. Duration
- 6h 38m
- When
- Every day
- Estimated price
- $130–430
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Brownsville Bus Station to Houston - Harrisburg Blvd
- Ave. Duration
- 6h 35m
- Frequency
- Twice daily
- Estimated price
- $75–95
- Schedules at
- Omnibus Express
Bus from Houston - Harrisburg Blvd to Miami
- Ave. Duration
- 24h 14m
- Frequency
- Once daily
- Estimated price
- $180–240
- Schedules at
- Omnibus Express
Bus from Brownsville to McAllen Central Station
- Ave. Duration
- 50 min
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- Omnibus Express
Bus from Brownsville to Harlingen Bus Station
- Ave. Duration
- 22 min
- Frequency
- Once daily
- Estimated price
- $35–50
- Schedules at
- Omnibus Express
Bus from Brownsville to Harlingen Bus Station
- Ave. Duration
- 22 min
- Frequency
- Once daily
- Estimated price
- $35–50
- Schedules at
- Omnibus Express
Bus from Houston - Harrisburg Blvd to Miami
- Ave. Duration
- 24h 14m
- Frequency
- Once daily
- Estimated price
- $180–240
- Schedules at
- Omnibus Express
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $19–40
- Website
- Greyhound
Bus from La Plaza at Brownsville to Houston Bus Station
- Ave. Duration
- 9h 30m
- Frequency
- 5 times a week
- Estimated price
- $60–120
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $19–40
- Website
- Greyhound
- Phone
- +1 956-682-3481
- [email protected]
- Website
- Valley Metro Texas
Bus from Brownsville to McAllen Central Station
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $2
- Website
- Valley Metro Texas
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from La Plaza at Brownsville to Houston Bus Station
- Ave. Duration
- 7h 40m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- Flixbus USA
- Phone
- +1 239-463-5733
- Website
- Key West Express
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- Key West Express
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