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How to get fromBrownsville to Santa Anaby plane, bus (Flixbus), bus, train, car, or bus (Greyhound)

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There are 8 ways to get from Brownsville to Santa Ana by plane, bus (Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Brownsville-South Padre Island International Airport

    best
    1. Fly from Brownsville-South Padre Island International Airport (BRO) to John Wayne Airport Orange County (SNA)plane plane BRO - SNA
    7h 28m
    $191–787

  2. Bus via Ciudad Juárez

    1. Take the bus from Matamoros to Chihuahuabus bus
    2. Take the bus from Chihuahua to Ciudad Juárezbus bus
    3. Take the bus from El Paso to 2474 E Florence Ave - Huntington Parkbus bus
    4. Take the bus from Huntington Park, CA - 2470 E Florence Ave to Santa Anabus bus
    34h 10m
    $308–408

  3. Bus, train via San Antonio

    1. Take the bus from Brownsville to San Antoniobus bus
    2. Take the train from San Antonio Station to Los Angelestrain train
    3. Take the train from Los Angeles to Santa Anatrain train
    36h 46m
    $521–1,075

  4. Drive 1,584.9 mi

    1. Drive from Brownsville to Santa Anacar car 1,584.9 mi
    25h 32m
    $290–418

  5. Bus to Mcallen Miller International Airport, fly

    1. Take the bus from Brownsville to McAllen Central Stationbus bus
    2. Fly from Mcallen Miller International Airport (MFE) to John Wayne Airport Orange County (SNA)plane plane MFE - SNA
    7h
    $226–996

  6. Bus to Rio Grande Valley International Airport, fly

    1. Take the bus from Brownsville to Harlingen Bus Stationbus bus
    2. Fly from Rio Grande Valley International Airport (HRL) to John Wayne Airport Orange County (SNA)plane plane HRL - SNA
    8h 37m
    $220–786

  7. Bus

    1. Take the bus from Matamoros to Ciudad Jiménezbus bus
    2. Take the bus from Ciudad Jiménez to Tijuanabus bus
    3. Take the bus from Tijuana - Plaza El Mexicano to Santa Anabus bus
    47h 32m
    $287–601

  8. Bus, train

    1. Take the bus from La Plaza at Brownsville to San Marcosbus bus
    2. Take the train from San Marcos Amtrak to Los Angelestrain train
    3. Take the train from Los Angeles to Santa Anatrain train
    2d
    $523–1,075

Brownsville to Santa Ana by bus and train

Calendar3Weekly Services
Duration2dAverage Duration
Ticket$523Cheapest Price
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Questions & Answers

Map of how to get from Brownsville to Santa Ana.ExpandLaunch map view
  • Distance: 1,345 mi
  • Duration: 7h 28m

What companies run services between Brownsville, TX, USA and Santa Ana, CA, USA?

American Airlines and United Airlines fly from Brownsville-South Padre Island International Airport (BRO) to John Wayne Airport Orange County (SNA) 5 times a day. Alternatively, you can take a bus from Matamoros to Santa Ana via Chihuahua, Ciudad Juárez Bus Station, Downtown El Paso, El Paso, and Huntington Park, CA - 2470 E Florence Ave in around 34h 10m.

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