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How to get fromBrussels to Guiseby train, bus, or car

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There are 4 ways to get from Brussels to Guise by train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, line 521 bus

    best
    1. Take the train from Brussel-Zuid / Bruxelles-Midi to St Quentintrain train 56
    2. Take the bus from Saint-Quentin - Gare Routiere to Guise - Jeanne D'arcbus bus 521
    3h 23m
    €29–48

  2. Drive  134.6 km

    cheapest
    1. Drive from Brussels to Guisecar car 134.6 km
    2h 16m
    €22–32

  3. Train, bus

    1. Take the train from Brussel-Zuid / Bruxelles-Midi to St Quentintrain train 56
    2. Take the bus from Saint-Quentin - Gare Routiere to Guise - Place Lesurbus bus 521 / ...
    3h 51m
    €29–48

  4. Train, line 527 bus

    1. Take the train from Bruxelles-Midi to Aulnoye Aymeriestrain train Otc / ...
    2. Take the bus from Le Cateau-Cambresis - Gare Sncf to Guise - Place Lesurbus bus 527
    4h 20m
    €23–36

Brussels to Guise by train and bus

Calendar5Weekly Services
Duration3h 23mAverage Duration
Ticket€29Cheapest Price
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Comparing Your Travel Options

Map of how to get from Brussels to Guise.ExpandLaunch map view
  • Distance: 184.5 km
  • Duration: 3h 23m

What companies run services between Brussels, Belgium and Guise, Hauts-de-France, France?

There is no direct connection from Brussels to Guise. However, you can take the train to St Quentin, walk to Saint-Quentin - Gare Routiere, then take the line 521 bus to Guise - Jeanne D'arc. Alternatively, you can drive from Brussels to Guise in around 2h 16m.

Train operators
Bus operators

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