There are 9 ways to get from Brussels to Mendrisio by plane, train, train (Eurostar, TGV), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Brussels Airport to Milano Malpensa Airport, train
best- Fly from Brussels Airport (BRU) to Milano Malpensa Airport (MXP)plane BRU - MXP
- Take the train from Malpensa Aeroporto T1 to Mendrisiotrain
5h 4mCHF 66–231Fly Brussels Airport to Milan Linate Airport, train
cheapest- Fly from Brussels Airport (BRU) to Milan Linate Airport (LIN)plane BRU - LIN
- Take the train from Monza to Mendrisiotrain
5h 50mCHF 37–192Train via Paris
- Take the train from Brussel-Zuid / Bruxelles-Midi to Paris Nordtrain
- Take the train from Paris Gare De Lyon to Zuerich Hbtrain Tgv
- Take the train from Zürich HB to Luganotrain Ec / ...
9h 24mCHF 214–444Bus via Lugano
- Take the bus from Brussels - Midi Train Station to Luganobus BlaBlaCar Bus
12h 16mCHF 66–110Drive 812.6 km
- Drive from Brussels to Mendrisiocar 812.6 km
8h 25mCHF 156–225Fly Brussels Airport to Zurich Airport, train
- Fly from Brussels Airport (BRU) to Zurich Airport (ZRH)plane BRU - ZRH
- Take the train from Zürich HB to Luganotrain
6h 24mCHF 136–315Train to Brussels South Charleroi Airport, fly to Il Caravaggio International Airport, bus, train
- Take the train from Bruxelles-Central to Charleroi-Centraltrain
- Fly from Brussels South Charleroi Airport (CRL) to Il Caravaggio International Airport (BGY)plane CRL - BGY
- Take the bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoiabus
- Take the train from Milano Centrale to Mendrisiotrain
7h 28mCHF 64–237Train
- Take the train from Bruxelles-Midi to Strasbourgtrain Trn
- Take the train from Strasbourg to Basel Sbbtrain Ter
- Take the train from Basel SBB to Bellinzonatrain Ec
- Take the train from Bellinzona to Mendrisiotrain S10 / ...
9h 48mCHF 167–356Bus
- Take the bus from Bruxelles - Rue du Progrès to Comobus
14h 57mCHF 130–178
Brussels to Mendrisio by train
Comparing Your Travel Options
The cheapest way to get from Brussels to Mendrisio is to bus via Lugano which costs SFr 65 - SFr 110 and takes 12h 16m.
The fastest way to get from Brussels to Mendrisio is to fly and train which takes 5h 4m and costs SFr 65 - SFr 240.
No, there is no direct bus from Brussels station to Mendrisio. However, there are services departing from Brussels - Midi Train Station and arriving at Lugano, Stazione via Lugano, Via Ciani/Cornaredo. The journey, including transfers, takes approximately 12h 16m.
No, there is no direct train from Brussels to Mendrisio. However, there are services departing from Brussel-Zuid / Bruxelles-Midi and arriving at Mendrisio via Paris Nord, Paris Gare De Lyon, Zürich HB and Lugano. The journey, including transfers, takes approximately 9h 24m.
The distance between Brussels and Mendrisio is 735 km. The road distance is 812.6 km.
The best way to get from Brussels to Mendrisio without a car is to train via Paris which takes 9h 24m and costs SFr 210 - SFr 450.
It takes approximately 5h 4m to get from Brussels to Mendrisio, including transfers.
Brussels to Mendrisio bus services, operated by BlaBlaCar Bus, depart from Brussels - Midi Train Station.
Brussels to Mendrisio train services, operated by Belgian Railways (NMBS/SNCB), depart from Bruxelles-Midi station.
The best way to get from Brussels to Mendrisio is to train via Paris which takes 9h 24m and costs SFr 210 - SFr 450. Alternatively, you can bus via Lugano, which costs SFr 65 - SFr 110 and takes 12h 16m.
What companies run services between Brussels, Belgium and Mendrisio, Switzerland?
You can take a train from Brussel-Zuid / Bruxelles-Midi to Mendrisio via Paris Nord, Paris Gare De Lyon, Zuerich Hb, Zürich HB, and Lugano in around 9h 24m. Alternatively, BlaBlaCar Bus operates a bus from Brussels - Midi Train Station to Lugano twice daily. Tickets cost CHF 60–100 and the journey takes 11h 35m.
- Website
- brusselsairlines.com
Flights from Brussels Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- CHF 60–200
Flights from Brussels Airport to Milan Linate Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- CHF 65–260
Flights from Brussels Airport to Zurich Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- CHF 75–170
- Website
- lufthansa.com
Flights from Brussels Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- CHF 70–260
Flights from Brussels Airport to Milano Malpensa Airport via Frankfurt
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- CHF 120–360
Flights from Brussels Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 3h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- CHF 140–420
Flights from Brussels Airport to Zurich Airport via Frankfurt
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- CHF 75–160
Flights from Brussels Airport to Zurich Airport via Munich
- Ave. Duration
- 3h 12m
- When
- Every day
- Estimated price
- CHF 75–190
- Website
- ryanair.com
Flights from Brussels South Charleroi Airport to Il Caravaggio International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- CHF 28–170
- Website
- ita-airways.com
Flights from Brussels Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- CHF 60–200
Flights from Brussels Airport to Milan Linate Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- CHF 65–260
- Website
- swiss.com
Flights from Brussels Airport to Milano Malpensa Airport via Zurich Airport
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- CHF 60–200
Flights from Brussels Airport to Zurich Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- CHF 75–170
- Website
- easyjet.com
Flights from Brussels Airport to Milan Linate Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- CHF 30–140
- Website
- klm.com
Flights from Brussels Airport to Milan Linate Airport via Amsterdam Schiphol
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- CHF 50–280
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- Trenord
Train from Monza to Mendrisio
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- CHF 2–4
- Website
- Trenord
Train from Bellinzona to Mendrisio
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 2–3
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 17–28
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Lugano
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 50–85
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Lugano
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 50–85
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 17–28
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Bellinzona
- Ave. Duration
- 2h 38m
- Frequency
- Every 3 hours
- Estimated price
- CHF 70–110
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Bellinzona to Mendrisio
- Ave. Duration
- 41 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 12–20
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +44 (0)3432 186 186
- Website
- Eurostar
Train from Brussel-Zuid / Bruxelles-Midi to Paris Nord
- Ave. Duration
- 1h 22m
- Frequency
- Hourly
- Estimated price
- CHF 110–180
- Website
- Eurostar
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Brussel-Zuid / Bruxelles-Midi to Paris Nord
- Ave. Duration
- 3h 4m
- Frequency
- 3 times a day
- Estimated price
- CHF 50–85
- Website
- Oui.SNCF
Train from Strasbourg to Basel Sbb
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- CHF 24–40
- Website
- Oui.SNCF
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Paris Gare De Lyon to Zuerich Hb
- Ave. Duration
- 4h 4m
- Frequency
- 5 times a day
- Estimated price
- CHF 110–170
- Website
- TGV inOui
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Bruxelles-Central to Charleroi-Central
- Ave. Duration
- 59 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 10–15
- Website
- Belgian Railways
Train from Bruxelles-Midi to Strasbourg
- Ave. Duration
- 3h 48m
- Frequency
- Twice a week
- Estimated price
- CHF 120–190
- Website
- Belgian Railways
- Phone
- +41 58 580 70 70
- Website
- Schweizerische Südostbahn AG
Train from Basel SBB to Bellinzona
- Ave. Duration
- 3h 56m
- Frequency
- Every 4 hours
- Estimated price
- CHF 60–95
- Schedules at
- Schweizerische Südostbahn AG
- Phone
- +49 (0) 7531 915109
- [email protected]
- Website
- SBB GmbH
Train from Basel SBB to Bellinzona
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- CHF 16–21
- Schedules at
- SBB GmbH
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Brussels - Midi Train Station to Lugano
- Ave. Duration
- 11h 35m
- Frequency
- Twice daily
- Estimated price
- CHF 60–100
- Website
- BlaBlaCar Bus
- [email protected]
- Website
- TERRAVISION
Bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoia
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 4–21
- Website
- TERRAVISION
- Phone
- 035.319366
- [email protected]
- Website
- orioshuttle.com
Bus from Milan Bergamo Orio al Serio Airport to Piazza Luigi di Savoia
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- CHF 10–13
- Schedules at
- orioshuttle.com
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Bruxelles - Rue du Progrès to Como
- Ave. Duration
- 13h 59m
- Frequency
- Once a week
- Estimated price
- CHF 120–180
- Website
- Onebus
Want to know more about travelling around Switzerland
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Brussels to Mendrisio bus services, operated by BlaBlaCar Bus, arrive at Lugano station.
Brussels to Mendrisio train services, operated by Belgian Railways (NMBS/SNCB), arrive at Strasbourg station.
Yes, the driving distance between Brussels to Mendrisio is 813 km. It takes approximately 8h 25m to drive from Brussels to Mendrisio.
Book your Brussels to Mendrisio train tickets online with Omio.
Book your Brussels to Mendrisio bus tickets online with Omio.
There are 5098+ hotels available in Mendrisio.

























































